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Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

An instance with a bad mask might make a composite image that uses it look fake. This encourages us to learn segmentation by generating realistic composite images. To achieve this, we propose a novel framework that exploits a new proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-11-14 Songmin Dai , Xiaoqiang Li , Lu Wang , Pin Wu , Weiqin Tong , Yimin Chen

Nuclei segmentation is both an important and in some ways ideal task for modern computer vision methods, e.g. convolutional neural networks. While recent developments in theory and open-source software have made these tools easier to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Aarno Oskar Vuola , Saad Ullah Akram , Juho Kannala

Pre-trained on a large and diverse dataset, the segment anything model (SAM) is the first promptable foundation model in computer vision aiming at object segmentation tasks. In this work, we evaluate SAM for the task of nuclear instance…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Kesi Xu , Lea Goetz , Nasir Rajpoot

Semantic and instance segmentation algorithms are two general yet distinct image segmentation solutions powered by Convolution Neural Network. While semantic segmentation benefits extensively from the end-to-end training strategy, instance…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Jianfeng Cao , Hong Yan

Nuclear segmentation is an important step for profiling aberrant regions of histology sections. However, segmentation is a complex problem as a result of variations in nuclear geometry (e.g., size, shape), nuclear type (e.g., epithelial,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Mina Khoshdeli , Bahram Parvin

Instance segmentation is an important task for biomedical and biological image analysis. Due to the complicated background components, the high variability of object appearances, numerous overlapping objects, and ambiguous object…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Dongnan Liu , Donghao Zhang , Yang Song , Heng Huang , Weidong Cai

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

Image segmentation, the process of partitioning an image into meaningful regions, plays a pivotal role in computer vision and medical imaging applications. Unsupervised segmentation, particularly in the absence of labeled data, remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Kovvuri Sai Gopal Reddy , Bodduluri Saran , A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

Instance segmentation with neural networks is an essential task in environment perception. In many works, it has been observed that neural networks can predict false positive instances with high confidence values and true positives with low…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Kira Maag , Matthias Rottmann , Serin Varghese , Fabian Hueger , Peter Schlicht , Hanno Gottschalk

Medical image segmentation is a critical aspect of modern medical research and clinical practice. Despite the remarkable performance of Convolutional Neural Networks (CNNs) in this domain, they inherently struggle to capture long-range…

Image and Video Processing · Electrical Eng. & Systems 2024-12-02 Jiashu Xu

Medical image segmentation is almost the most important pre-processing procedure in computer-aided diagnosis but is also a very challenging task due to the complex shapes of segments and various artifacts caused by medical imaging, (i.e.,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Hao Du , Qihua Dong , Yan Xu , Jing Liao

While large models have achieved significant progress in computer vision, challenges such as optimization complexity, the intricacy of transformer architectures, computational constraints, and practical application demands highlight the…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Juntao Jiang , Mengmeng Wang , Huizhong Tian , Lingbo Cheng , Yong Liu

Semi-supervised segmentation methods have demonstrated promising results in natural scenarios, providing a solution to reduce dependency on manual annotation. However, these methods face significant challenges when directly applied to…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Ye Zhang , Ziyue Wang , Yifeng Wang , Hao Bian , Linghan Cai , Hengrui Li , Lingbo Zhang , Yongbing Zhang

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Recent studies have demonstrated the superiority of deep learning in medical image analysis, especially in cell instance segmentation, a fundamental step for many biological studies. However, the excellent performance of the neural networks…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Huaqian Wu , Nicolas Souedet , Caroline Jan , Cédric Clouchoux , Thierry Delzescaux

In surgical procedures, correct instrument counting is essential. Instance segmentation is a location method that locates not only an object's bounding box but also each pixel's specific details. However, obtaining mask-level annotations is…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Zhen Sun , Huan Xu , Jinlin Wu , Zhen Chen , Zhen Lei , Hongbin Liu

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…