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The emergence of machine learning (ML) has led to a transformative shift in software techniques and guidelines for building software applications that support data analysis process activities such as data ingestion, modeling, and…
Machine Learning is transforming medical research by improving diagnostic accuracy and personalizing treatments. General ML models trained on large datasets identify broad patterns across populations, but their effectiveness is often…
A predictive model makes outcome predictions based on some given features, i.e., it estimates the conditional probability of the outcome given a feature vector. In general, a predictive model cannot estimate the causal effect of a feature…
Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…
Machine Learning and AI have the potential to transform data-driven scientific discovery, enabling accurate predictions for several scientific phenomena. As many scientific questions are inherently causal, this paper looks at the causal…
The crafting of machine learning (ML) based systems requires statistical control throughout its life cycle. Careful quantification of business requirements and identification of key factors that impact the business requirements reduces the…
With increasing data availability, causal effects can be evaluated across different data sets, both randomized controlled trials (RCTs) and observational studies. RCTs isolate the effect of the treatment from that of unwanted (confounding)…
As a key component to intuitive cognition and reasoning solutions in human intelligence, causal knowledge provides great potential for reinforcement learning (RL) agents' interpretability towards decision-making by helping reduce the…
External validation is often recommended to ensure the generalizability of ML models. However, it neither guarantees generalizability nor equates to a model's clinical usefulness (the ultimate goal of any clinical decision-support tool).…
Reinforcement Learning (RL) faces significant challenges in adaptive healthcare interventions, such as dementia care, where data is scarce, decisions require interpretability, and underlying patient-state dynamic are complex and causal in…
Machine maintenance is a challenging operational problem, where the goal is to plan sufficient preventive maintenance to avoid machine failures and overhauls. Maintenance is often imperfect in reality and does not make the asset as good as…
Machine learning (ML) has emerged as a powerful tool for tackling complex regression and classification tasks, yet its success often hinges on the quality of training data. This study introduces an ML paradigm inspired by domain knowledge…
Recent years have seen many advances in methods for causal structure learning from data. The empirical assessment of such methods, however, is much less developed. Motivated by this gap, we pose the following question: how can one assess,…
In large observational studies, the case-cohort design is commonly used to reduce the cost associated with covariate measurement. For survival outcomes, literature has suggested that the restricted mean survival time (RMST) be a more…
Externally controlled trials (ECTs) are increasingly used when randomized controls are infeasible, unethical, or insufficient, including applications in rare diseases, oncology, pediatrics, and post-approval effectiveness research. Although…
Predictive models in acute care settings must be able to immediately recognize precipitous changes in a patient's status when presented with data reflecting such changes. Recurrent neural networks (RNNs) have become common for training and…
Existing work on continual learning (CL) is primarily devoted to developing algorithms for models trained from scratch. Despite their encouraging performance on contrived benchmarks, these algorithms show dramatic performance drops in…
Performance monitoring of machine learning (ML)-based risk prediction models in healthcare is complicated by the issue of confounding medical interventions (CMI): when an algorithm predicts a patient to be at high risk for an adverse event,…
Despite the advantages of multi-agent reinforcement learning (MARL) for wireless use case such as medium access control (MAC), their real-world deployment in Internet of Things (IoT) is hindered by their sample inefficiency. To alleviate…
Recent applications of machine learning (ML) reveal a noticeable shift from its use for predictive modeling in the sense of a data-driven construction of models mainly used for the purpose of prediction (of ground-truth facts) to its use…