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Methods that infer causal dependence from observational data are central to many areas of science, including medicine, economics, and the social sciences. A variety of theoretical properties of these methods have been proven, but empirical…

Methodology · Statistics 2021-07-08 Amanda Gentzel , Purva Pruthi , David Jensen

Disruptions in clinical trials may be due to external events like pandemics, warfare, and natural disasters. Resulting complications may lead to unforeseen intercurrent events (events that occur after treatment initiation and affect the…

Applications · Statistics 2024-08-20 Rachael V. Phillips , Mark J. van der Laan

Nowadays, real-world applications often face streaming data, which requires the learning system to absorb new knowledge as data evolves. Continual Learning (CL) aims to achieve this goal and meanwhile overcome the catastrophic forgetting of…

Machine Learning · Computer Science 2024-04-24 Da-Wei Zhou , Hai-Long Sun , Jingyi Ning , Han-Jia Ye , De-Chuan Zhan

Reinforcement learning (RL) and causal modelling naturally complement each other. The goal of causal modelling is to predict the effects of interventions in an environment, while the goal of reinforcement learning is to select interventions…

Machine Learning · Computer Science 2024-07-12 Oliver Schulte , Pascal Poupart

Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains.…

Machine Learning · Computer Science 2026-05-27 Nikita Dhawan , Arnav Paruthi , Andrew Kim , Lovedeep Gondara , Jekaterina Novikova , Chris J. Maddison

The need for algorithms able to solve Reinforcement Learning (RL) problems with few trials has motivated the advent of model-based RL methods. The reported performance of model-based algorithms has dramatically increased within recent…

Machine Learning · Computer Science 2022-03-22 Giacomo Arcieri , David Wölfle , Eleni Chatzi

Randomized controlled trials (RCTs) are the accepted standard for treatment effect estimation but they can be infeasible due to ethical reasons and prohibitive costs. Single-arm trials, where all patients belong to the treatment group, can…

Recent work has demonstrated that controlled pretraining experiments are a powerful tool for studying the relationship between training data and large language model (LLM) behavior. However, the computational cost of pretraining presents a…

Computation and Language · Computer Science 2026-03-03 Sebastian Bordt , Martin Pawelczyk

The causal inference model proposed by Lee (2008) for the regression discontinuity design (RDD) relies on assumptions that imply the continuity of the density of the assignment (running) variable. The test for this implication is commonly…

Econometrics · Economics 2024-06-28 Federico Crippa

Statistical machine learning algorithms have achieved state-of-the-art results on benchmark datasets, outperforming humans in many tasks. However, the out-of-distribution data and confounder, which have an unpredictable causal relationship,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-31 Changjie Lu

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects…

Methodology · Statistics 2024-04-23 Kosuke Imai , Michael Lingzhi Li

In causal analysis, understanding the causal mechanisms through which an intervention or treatment affects an outcome is often of central interest. We propose a test to evaluate (i) whether the causal effect of a treatment that is randomly…

Econometrics · Economics 2026-03-05 Martin Huber , Kevin Kloiber , Lukáš Lafférs

Randomized experiments (a.k.a. A/B tests) are a powerful tool for estimating treatment effects, to inform decisions making in business, healthcare and other applications. In many problems, the treatment has a lasting effect that evolves…

Machine Learning · Computer Science 2022-10-17 Ziyang Tang , Yiheng Duan , Stephanie Zhang , Lihong Li

Randomised controlled trials (RCTs) are the most effective approach to causal discovery, but in many circumstances it is impossible to conduct RCTs. Therefore observational studies based on passively observed data are widely accepted as an…

Artificial Intelligence · Computer Science 2016-11-11 Jiuyong Li , Thuc Duy Le , Lin Liu , Jixue Liu , Zhou Jin , Bingyu Sun , Saisai Ma

Model-driven engineering problems often require complex model transformations (MTs), i.e., MTs that are chained in extensive sequences. Pertinent examples of such problems include model synchronization, automated model repair, and design…

Software Engineering · Computer Science 2025-08-08 Kyanna Dagenais , Istvan David

Causal mediation analysis in cluster-randomized trials (CRTs) is complicated by the presence of multiple mediators, intracluster correlation, and within-cluster interference. Existing mediation methods often fall short in accommodating…

Methodology · Statistics 2026-04-14 Jiaqi Tong , Chao Cheng , Fan Li

Machine learning (ML) has penetrated various fields in the era of big data. The advantage of collaborative machine learning (CML) over most conventional ML lies in the joint effort of decentralized nodes or agents that results in better…

Machine Learning · Computer Science 2022-09-13 Shengwen Ding , Chenhui Hu

Large language models (LLMs) have shown various ability on natural language processing, including problems about causality. It is not intuitive for LLMs to command causality, since pretrained models usually work on statistical associations,…

Computation and Language · Computer Science 2024-08-27 Chenyang Zhang , Haibo Tong , Bin Zhang , Dongyu Zhang

Testing practices within the machine learning (ML) community have centered around assessing a learned model's predictive performance measured against a test dataset, often drawn from the same distribution as the training dataset. While…

Machine Learning · Computer Science 2021-12-07 Negar Rostamzadeh , Ben Hutchinson , Christina Greer , Vinodkumar Prabhakaran

The penultimate goal for developing machine learning models in supply chain management is to make optimal interventions. However, most machine learning models identify correlations in data rather than inferring causation, making it…

Machine Learning · Computer Science 2025-01-31 Mateusz Wyrembek , George Baryannis , Alexandra Brintrup