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The increasing global cancer burden necessitates exploration of effective and affordable treatments. Epigallocatechin gallate (EGCG), a green tea catechin, and piperine, a black pepper alkaloid, have demonstrated promising anti-cancer…
The global pandemic has significantly increased the demand for personal protective equipment (PPE). The antimicrobial coating has been broadly applied to PPE to improve its prevention capability, especially after prolonged usage. However,…
As antibiotic-resistant bacterial strains are rapidly spreading worldwide, infections caused by these strains are emerging as a global crisis causing the death of millions of people every year. Antimicrobial Peptides (AMPs) are one of the…
Antimicrobial peptides (AMPs) have exhibited unprecedented potential as biomaterials in combating multidrug-resistant bacteria. Despite the increasing adoption of artificial intelligence for novel AMP design, challenges pertaining to…
Melanoma is an aggressive and highly metastatic cancer that exhibits stubborn resistance to conventional therapies, highlighting the need for novel treatments. Existing therapeutic strategies often suffer from systemic toxicity, poor…
Pathogenic Gram-negative bacteria have developed resistance to antibiotics due to their ability in creating an envelope on the outer layer of lipooligosaccharides (LOS). The cationic phosphoethanolamine (PEA) decoration of LOS lipid A is…
We study the newly reported hidden-charm pentaquark candidates $P_c(4312)$, $P_c(4440)$ and $P_c(4457)$ from the LHCb Collaboration, in the framework of the effective-range expansion and resonance compositeness relations. The scattering…
Ubiquitin, discovered less than 50 years ago, tags thousands of diseased proteins for destruction. It is small (only 76 amino acids), and is found unchanged in mammals, birds, fish and even worms. Key features of its functionality are…
Diabetes mellitus is a chronic metabolic disorder that necessitates novel therapeutic innovations due to its gradual progression and the onset of various metabolic complications. Research indicates that Ficus religiosa is a conventional…
While the emerging evidence indicates that the pathogenesis of Parkinson's disease (PD) is strongly correlated to the accumulation of alpha-synuclein ({\alpha}-syn) aggregates, there has been no clinical success in anti-aggregation agents…
This study examines the phytochemical characteristics of Ayurvedic products. An analysis was performed on Kottakkal Ayurveda Triphala (T), Kottakkal Ayurveda Hinguvachadi Churnam (H), and Kottakkal Ayurveda Jirakadyarishtam (J) using GC-MS…
The objective of this study was to determine the effect of feeding an antimicrobial association to males broiler chickens from 0 to 14 days of age on the performance and clinical signs of bacterial processes. Two treatments were tested: a…
Dopamine levels are linked to neurological illnesses like Parkinson's and Alzheimer's. Thus, reliable and sensitive detection of dopamine is crucial for early diagnosis and surveillance of neurodegenerative diseases. Non-noble-metal-based…
Limited accessibility to neurological care leads to underdiagnosed Parkinson's Disease (PD), preventing early intervention. Existing AI-based PD detection methods primarily focus on unimodal analysis of motor or speech tasks, overlooking…
The evolution of drug-resistant microbial species is one of the major challenges to global health. The development of new antimicrobial treatments such as antimicrobial peptides needs to be accelerated to combat this threat. However, the…
The interaction between the bacterial S-protein SbpA on different types of lipid membranes has been studied using atomic force microscopy, transmission electron microscopy, and quartz crystal microbalance with dissipation. On one hand, It…
We discuss about the antibacterial activities of copper nanoparticles on both Gram negative and Gram positive bacteria in this investigation. First time, we increase its antibacterial activities by using electrical power while on…
In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm$^{2}$ dose). Peaks in the Raman fingerprint region…
High-efficiency single-photon detection in the microwave domain is a key enabling technology for quantum sensing, communication, and information processing. However, the extremely low energy of microwave photons (~{\mu}eV) presents a…
Atomic configurations of two or three Pd substituents on the Au(111) surface are investigated using the first-principles pseudopotential plane wave approach. Pd atoms are found to form second neighborhoods on PdAu(111). The Pd-d band…