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Protein-DNA interactions are crucial for all biological processes. One of the most important fundamental aspects of these interactions is the process of protein searching and recognizing specific binding sites on DNA. A large number of…

Subcellular Processes · Quantitative Biology 2015-09-30 Martin Lange , Maria Kochugaeva , Anatoly B. Kolomeisky

Medical image analysis plays a key role in precision medicine as it allows the clinicians to identify anatomical abnormalities and it is routinely used in clinical assessment. Data curation and pre-processing of medical images are critical…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Sergey Primakov , Elizaveta Lavrova , Zohaib Salahuddin , Henry C Woodruff , Philippe Lambin

WavePacket is an open-source program package for the numerical simulation of quantum-mechanical dynamics. It can be used to solve time-independent or time-dependent linear Schr\"odinger and Liouville-von Neumann-equations in one or more…

Quantum Physics · Physics 2023-02-09 Burkhard Schmidt , Ulf Lorenz

Quantum plasma physics is a rapidly evolving research field with a very inter-disciplinary scope of potential applications, ranging from nano-scale science in condensed matter to the vast scales of astrophysical objects. The theoretical…

Plasma Physics · Physics 2013-10-02 Shabbir A. Khan , Michael Bonitz

Quantum computing promises the possibility of studying the real-time dynamics of nonperturbative quantum field theories while avoiding the sign problem that obstructs conventional lattice approaches. Current and near-future quantum devices…

High Energy Physics - Lattice · Physics 2021-12-15 Christopher Culver , David Schaich

In The Cancer Genome Atlas (TCGA) data set, there are many interesting nonlinear dependencies between pairs of genes that reveal important relationships and subtypes of cancer. Such genomic data analysis requires a rapid, powerful and…

Applications · Statistics 2022-11-30 Siqi Xiang , Wan Zhang , Siyao Liu , Katherine A. Hoadley , Charles M. Perou , Kai Zhang , J. S. Marron

Grounded theory (GT) is a qualitative research method for building theory grounded in data. GT uses textual and numeric data and follows various stages of coding or tagging data for sense-making, such as open coding and selective coding.…

Computation and Language · Computer Science 2020-03-31 Bell Raj Eapen , Norm Archer , Kamran Sartipi

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

Major advancements in fields as diverse as biology and quantum computing have relied on a multitude of microscopic techniques. All optical, electron and scanning probe microscopy advanced with new detector technologies and integration of…

Instrumentation and Detectors · Physics 2023-03-01 Rama Vasudevan , Mani Valleti , Maxim Ziatdinov , Gerd Duscher , Suhas Somnath

We discuss the QDN (quantized detector network) approach to the formulation and interpretation of quantum mechanics. This approach gives us a system-free approach to quantum physics. By this, we mean having a proper emphasis on those…

Quantum Physics · Physics 2007-05-23 George Jaroszkiewicz

Charge transport through a short DNA oligomer (Dickerson dodecamer) in presence of structural fluctuations is investigated using a hybrid computational methodology based on a combination of quantum mechanical electronic structure…

Soft Condensed Matter · Physics 2015-05-14 R. Gutierrez , R. Caetano , P. B. Woiczikowski , T. Kubar , M. Elstner , G. Cuniberti

Kwant is a Python package for numerical quantum transport calculations. It aims to be an user-friendly, universal, and high-performance toolbox for the simulation of physical systems of any dimensionality and geometry that can be described…

Mesoscale and Nanoscale Physics · Physics 2015-10-12 Christoph W. Groth , Michael Wimmer , Anton R. Akhmerov , Xavier Waintal

We use the benefits and components of classical computers every day. However, there are many types of problems which, as they grow in size, their computational complexity grows larger than classical computers will ever be able to solve.…

DNA exhibits remarkable potential as a data storage solution due to its impressive storage density and long-term stability, stemming from its inherent biomolecular structure. However, developing this novel medium comes with its own set of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Trung Hieu Le , Xavier Pic , Jeremy Mateos , Marc Antonini

In the forthcoming years the LHC experiments are going to be upgraded to benefit from the substantial increase of the LHC instantaneous luminosity, which will lead to larger, denser events, and, consequently, greater complexity in…

Quantum Physics · Physics 2026-03-10 Matteo Argenton , Laura Cappelli , Concezio Bozzi

Quantum sensing exploits quantum phenomena to enhance the detection and estimation of classical parameters of physical systems and biological entities, particularly so as to overcome the inefficiencies of its classical counterparts. A…

Genetic engineering of cells has a range of applications in treating incurable diseases. Plasmid DNA is a popular choice of nucleic acid for cell engineering due to its low cost and stability. However, plasmid DNA must survive the…

Biological Physics · Physics 2025-10-06 Leyla Akh , Apresio K. Fajrial , Benjamin Seelbinder , Xin Xu , Wei Tan , Jill Slansky , Corey P. Neu , Xiaoyun Ding

We present a theoretical study of the physical properties of cationic lipid-DNA (CL-DNA) complexes - a promising synthetically based nonviral carrier of DNA for gene therapy. The study is based on a coarse-grained molecular model, which is…

Soft Condensed Matter · Physics 2007-05-23 Oded Farago , Niels Grønbech-Jensen

Quantum dots (QDs) have emerged as promising nanomaterials with unique optical and physical properties, making them highly attractive for various applications in biomedicine. This review provides a comprehensive overview of the types, modes…

Charge inversion of a DNA double helix by an oppositely charged flexible polyelectrolyte (PE) is widely used for gene delivery. It is considered here in terms of discrete charges of DNA. We concentrate on the worst scenario case when in the…

Soft Condensed Matter · Physics 2009-11-07 T. T. Nguyen , B. I. Shklovskii
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