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Results from Randomized Controlled Trials (RCTs) establish the comparative effectiveness of interventions, and are in turn critical inputs for evidence-based care. However, results from RCTs are presented in (often unstructured) natural…

Computation and Language · Computer Science 2023-07-19 Somin Wadhwa , Jay DeYoung , Benjamin Nye , Silvio Amir , Byron C. Wallace

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Computation and Language · Computer Science 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

Although Large Language Models (LLMs) have shown promising performance in healthcare-related applications, their deployment in the medical domain poses unique challenges of ethical, regulatory, and technical nature. In this study, we employ…

Computers and Society · Computer Science 2025-01-22 Giorgia Carra , Bogdan Kulynych , François Bastardot , Daniel E. Kaufmann , Noémie Boillat-Blanco , Jean Louis Raisaro

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

The integration of Large Language Models (LLMs) into healthcare holds significant potential to enhance diagnostic accuracy and support medical treatment planning. These AI-driven systems can analyze vast datasets, assisting clinicians in…

Computation and Language · Computer Science 2025-04-15 Diogo Sousa , Guilherme Barbosa , Catarina Rocha , Dulce Oliveira

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

The large set of technical documentation of legacy accelerator systems, coupled with the retirement of experienced personnel, underscores the urgent need for efficient methods to preserve and transfer specialized knowledge. This paper…

Information Retrieval · Computer Science 2025-09-03 Qing Dai , Rasmus Ischebeck , Maruisz Sapinski , Adam Grycner

Large language models (LLMs) excel at text generation, but their ability to handle clinical classification tasks involving structured data, such as time series, remains underexplored. In this work, we adapt instruction-tuned LLMs using…

Computation and Language · Computer Science 2025-09-18 Iyadh Ben Cheikh Larbi , Ajay Madhavan Ravichandran , Aljoscha Burchardt , Roland Roller

Clinical decision-making depends on expert reasoning, which is guided by standardized, evidence-based guidelines. However, translating these guidelines into automated clinical decision support systems risks inaccuracy and importantly, loss…

Large language models (LLMs) have become increasingly popular in medical domains to assist physicians with a variety of clinical and operational tasks. Given the fast-paced and high-stakes environment of emergency departments (EDs), small…

Computation and Language · Computer Science 2025-10-07 Zirui Wang , Jiajun Wu , Braden Teitge , Jessalyn Holodinsky , Steve Drew

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

Building high-quality datasets and labeling query-document relevance are essential yet resource-intensive tasks, requiring detailed guidelines and substantial effort from human annotators. This paper explores the use of small, fine-tuned…

Information Retrieval · Computer Science 2025-04-15 Quentin Fitte-Rey , Matyas Amrouche , Romain Deveaud

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

Computation and Language · Computer Science 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Text embeddings have become an essential part of a variety of language applications. However, methods for interpreting, exploring and reversing embedding spaces are limited, reducing transparency and precluding potentially valuable…

Computation and Language · Computer Science 2026-01-27 Brian Ondov , Chia-Hsuan Chang , Yujia Zhou , Mauro Giuffrè , Hua Xu

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Fine-tuning of Large Language Models (LLMs) has become the default practice for improving model performance on a given task. However, performance improvement comes at the cost of training on vast amounts of annotated data which could be…

Computation and Language · Computer Science 2025-04-25 Jose G. Moreno , Jesus Lovon , M'Rick Robin-Charlet , Christine Damase-Michel , Lynda Tamine