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Large language models (LLMs) have performed well across various clinical natural language processing tasks, despite not being directly trained on electronic health record (EHR) data. In this work, we examine how popular open-source LLMs…

Computation and Language · Computer Science 2025-05-26 Furong Jia , David Sontag , Monica Agrawal

Large Language Models (LLMs) have shown promising results on machine translation for high resource language pairs and domains. However, in specialised domains (e.g. medical) LLMs have shown lower performance compared to standard neural…

Computation and Language · Computer Science 2025-07-31 Miguel Rios

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

Biomedical triple extraction systems aim to automatically extract biomedical entities and relations between entities. The exploration of applying large language models (LLM) to triple extraction is still relatively unexplored. In this work,…

Computation and Language · Computer Science 2024-04-30 Mingchen Li , Huixue Zhou , Rui Zhang

Large language models (LLMs) are becoming useful in many domains due to their impressive abilities that arise from large training datasets and large model sizes. However, research on LLM-based approaches to document inconsistency detection…

Computation and Language · Computer Science 2026-04-09 Nelvin Tan , Yaowen Zhang , James Asikin Cheung , Fusheng Liu , Yu-Ching Shih , Dong Yang

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

Since the inception of the Transformer architecture in 2017, Large Language Models (LLMs) such as GPT and BERT have evolved significantly, impacting various industries with their advanced capabilities in language understanding and…

Computation and Language · Computer Science 2024-05-30 Yining Huang , Keke Tang , Meilian Chen , Boyuan Wang

Large language models (LLMs) hold great promise in summarizing medical evidence. Most recent studies focus on the application of proprietary LLMs. Using proprietary LLMs introduces multiple risk factors, including a lack of transparency and…

This paper presents a novel approach to epidemic surveillance, leveraging the power of Artificial Intelligence and Large Language Models (LLMs) for effective interpretation of unstructured big data sources, like the popular ProMED and WHO…

Computational Engineering, Finance, and Science · Computer Science 2024-08-27 Sergio Consoli , Peter Markov , Nikolaos I. Stilianakis , Lorenzo Bertolini , Antonio Puertas Gallardo , Mario Ceresa

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

The rapid increase in unstructured data across various fields has made multi-document comprehension and summarization a critical task. Traditional approaches often fail to capture relevant context, maintain logical consistency, and extract…

Computation and Language · Computer Science 2024-09-30 Aditi Godbole , Jabin Geevarghese George , Smita Shandilya

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman

Digital technologies have long been explored as a complement to standard procedure in mental health research and practice, ranging from the management of electronic health records to app-based interventions. The recent emergence of large…

Radiology reports capture crucial longitudinal information on tumor burden, treatment response, and disease progression, yet their unstructured narrative format complicates automated analysis. While large language models (LLMs) have…

Computation and Language · Computer Science 2026-03-12 Luc Builtjes , Alessa Hering

This paper presents a comprehensive evaluation of cost-efficient Large Language Models (LLMs) for diverse biomedical tasks spanning both text and image modalities. We evaluated a range of closed-source and open-source LLMs on tasks such as…

Computation and Language · Computer Science 2025-07-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma
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