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Large-scale diffusion models have achieved state-of-the-art results on text-to-image synthesis (T2I) tasks. Despite their ability to generate high-quality yet creative images, we observe that attribution-binding and compositional…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Weixi Feng , Xuehai He , Tsu-Jui Fu , Varun Jampani , Arjun Akula , Pradyumna Narayana , Sugato Basu , Xin Eric Wang , William Yang Wang

Genotype-to-Phenotype prediction can promote advances in modern genomic research and crop improvement, guiding precision breeding and genomic selection. However, high-dimensional nonlinear features often hinder the accuracy of…

Genomics · Quantitative Biology 2025-02-27 Zeyuan Zhou , Siyuan Chen , Xinzhang Wu , Jisen Zhang , Yunxuan Dong

Robust genotype-to-phenotype (G2P) prediction is essential for accelerating breeding decisions and genetic gain. However, it remains challenging to measure complex traits under variable field conditions and across years. In this study, we…

Genomics · Quantitative Biology 2026-05-11 Yibin Wang , Murukarthick Jayakodi , Silvas Kirubakaran , Ambika Chandra , Azlan Zahid

Generative artificial intelligence (AI) refers to algorithms that create synthetic but realistic output. Diffusion models currently offer state of the art performance in generative AI for images. They also form a key component in more…

Machine Learning · Computer Science 2023-12-27 Catherine F. Higham , Desmond J. Higham , Peter Grindrod

Plant phenotyping (Guo et al. 2021; Pieruschka et al. 2019) focuses on studying the diverse traits of plants related to the plants' growth. To be more specific, by accurately measuring the plant's anatomical, ontogenetical, physiological…

Machine Learning · Computer Science 2022-01-17 Jun Wu , Elizabeth A. Ainsworth , Sheng Wang , Kaiyu Guan , Jingrui He

Linear mixed models (LMMs) are a powerful and established tool for studying genotype-phenotype relationships. A limiting assumption of LMMs is that the residuals are Gaussian distributed, a requirement that rarely holds in practice.…

Genomics · Quantitative Biology 2014-08-10 Nicolo Fusi , Christoph Lippert , Neil D. Lawrence , Oliver Stegle

Post-genomic research deals with challenging problems in screening genomes of organisms for particular functions or potential for being the targets of genetic engineering for desirable biological features. 'Phenotyping' of wild type and…

Quantitative Methods · Quantitative Biology 2010-09-06 Hesam T. Dashti , Jernej Tonejc , Adel Ardalan , Alireza F. Siahpirani , Sabrina Guettes , Zohreh Sharif , Liya Wang , Amir H. Assadi

Extensive pre-training with large data is indispensable for downstream geometry and semantic visual perception tasks. Thanks to large-scale text-to-image (T2I) pretraining, recent works show promising results by simply fine-tuning T2I…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Guangkai Xu , Yongtao Ge , Mingyu Liu , Chengxiang Fan , Kangyang Xie , Zhiyue Zhao , Hao Chen , Chunhua Shen

Seed phenotyping is the idea of analyzing the morphometric characteristics of a seed to predict the behavior of the seed in terms of development, tolerance and yield in various environmental conditions. The focus of the work is the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Venkat Margapuri , Mitchell Neilsen

We show how field- and information theory can be used to quantify the relationship between genotype and phenotype in cases where phenotype is a continuous variable. Given a sample population of phenotype measurements, from various known…

Quantitative Methods · Quantitative Biology 2022-06-10 Jonathan Wattis , Sian Bray , Panagiota Kyratzi , Cyril Rauch

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Graph Domain Adaptation (GDA) aims to bridge distribution shifts between domains by transferring knowledge from well-labeled source graphs to given unlabeled target graphs. One promising recent approach addresses graph transfer by…

Machine Learning · Computer Science 2026-02-12 Wei Chen , Xingyu Guo , Shuang Li , Yan Zhong , Zhao Zhang , Fuzhen Zhuang , Hongrui Liu , Libang Zhang , Guo Ye , Huimei He

Recently, diffusion models have achieved great success in image synthesis. However, when it comes to the layout-to-image generation where an image often has a complex scene of multiple objects, how to make strong control over both the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Guangcong Zheng , Xianpan Zhou , Xuewei Li , Zhongang Qi , Ying Shan , Xi Li

This survey reviews the progress of diffusion models in generating images from text, ~\textit{i.e.} text-to-image diffusion models. As a self-contained work, this survey starts with a brief introduction of how diffusion models work for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Chenshuang Zhang , Chaoning Zhang , Mengchun Zhang , In So Kweon , Junmo Kim

Object pose estimation plays a vital role in embodied AI and computer vision, enabling intelligent agents to comprehend and interact with their surroundings. Despite the practicality of category-level pose estimation, current approaches…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Jiyao Zhang , Mingdong Wu , Hao Dong

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Text-to-image (T2I) diffusion models lack an efficient mechanism for early quality assessment, leading to costly trial-and-error in multi-generation scenarios such as prompt iteration, agent-based generation, and flow-grpo. We reveal a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Benlei Cui , Bukun Huang , Zhizeng Ye , Xuemei Dong , Tuo Chen , Hui Xue , Dingkang Yang , Longtao Huang , Jingqun Tang , Haiwen Hong

Detectors often suffer from performance drop due to domain gap between training and testing data. Recent methods explore diffusion models applied to domain generalization (DG) and adaptation (DA) tasks, but still struggle with large…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Boyong He , Yuxiang Ji , Zhuoyue Tan , Liaoni Wu

Accurate survival prediction is essential for personalized cancer treatment. However, genomic data - often a more powerful predictor than pathology data - is costly and inaccessible. We present the cross-modal genomic feature translation…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Akhila Krishna , Nikhil Cherian Kurian , Abhijeet Patil , Amruta Parulekar , Amit Sethi

An unsolved fundamental problem in biology and ecology is to predict observable traits (phenotypes) from a new genetic constitution (genotype) of an organism under environmental perturbations (e.g., drug treatment). The emergence of…

Machine Learning · Computer Science 2020-10-13 Di He , Lei Xie