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Ultrasound vascular imaging is limited by acoustic diffraction, restricting visualization of microvessels essential for understanding organ function and disease. Label-free super-resolution methods exploiting endogenous red blood cells have…
Minfrared spectroscopic imaging (MIRSI) is an emerging class of label-free, biochemically quantitative technologies targeting digital histopathology. Conventional histopathology relies on chemical stains that alter tissue color. This…
Various imaging techniques have significantly enhanced our ability to visualize objects embedded within complex media such as biological tissues, fog, atmosphere, or various turbid media. Optical imaging, in particular, offers multiple…
We present VIINTER, a method for view interpolation by interpolating the implicit neural representation (INR) of the captured images. We leverage the learned code vector associated with each image and interpolate between these codes to…
A new frontier in optics research has been opened by the recent developments in non-perturbative optical modulation in both time and space that creates temporal boundaries generating ``time-reflection'' and ``time-refraction'' of light in…
Hydrogen detection is of great importance in chemical and energy industries. Optical fiber hydrogen sensors show flexibility and compactness and have the potential for distributed analysis. However, traditional fiber sensors encounter a…
Label-free biosensors enable the monitoring of biomolecular interactions in real-time, which is key to the analysis of the binding characteristics of biomolecules. While refractometric optical biosensors are sensitive and well-established,…
We propose a novel architecture with a remote phosphor based modular and compact light source in a non-contact dermoscope prototype for skin cancer screening. The spectrum and color temperature of the output light can easily and…
Ultrafast non-equilibrium dynamics offer a route to study the microscopic interactions that govern macroscopic behavior. In particular, photo-induced phase transitions (PIPTs) in solids provide a test case for how forces, and the resulting…
Dissipative Kerr solitons formed in high-$Q$ optical microresonators provide a route to miniaturized optical frequency combs that can revolutionize precision measurements, spectroscopy, sensing, and communication. In the last decade, a…
Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…
Photoacoustic tomography (PAT) enables non-invasive cross-sectional imaging of biological tissues, but it fails to map the spatial variation of speed-of-sound (SOS) within tissues. While SOS is intimately linked to density and elastic…
Volumetric reconstruction of label-free living cells from non-destructive optical microscopic images reveals cellular metabolism in native environments. However, current optical tomography techniques require hundreds of 2D images to…
We have demonstrated a high temperature vapor cell for absorption spectroscopy on the Ca intercombination line. The cell uses a dual chamber design to achieve the high temperatures necessary for an optically dense vapor while avoiding the…
Optical diffraction tomography (ODT) has emerged as an important label-free tool in biomedicine to measure the three-dimensional (3D) structure of a biological sample. In this paper, we describe ODT using second-harmonic generation (SHG)…
Chiral molecule sensing is currently performed using chromatography, electrophoresis, enzymatic-assays, mass spectrometry, and chiroptical sensing techniques. Currently polarimetry is the only method having in-vivo sensing capabilities,…
Room temperature detection of molecular vibrations in the mid-infrared (MIR, $\lambda$ =3-30$\mu$m) has numerous applications including real-time gas sensing, chemical reactivity, medical imaging, astronomical surveys, and quantum…
Optical spectroscopy with broadband femtosecond laser pulses often involves simultaneous excitation of multiple molecular species with close resonance frequencies. Interpreting the collective optical response from molecular mixtures…
Infrared (IR) multiple-angle incidence resolution spectrometry (IR-MAIRS) is a recently developed spectroscopic technique that combines oblique incidence transmission measurements and chemometrics (multivariate analysis) to obtain both pure…
Devices based on photonic integrated circuits play a crucial role in the development of low-cost, high-performance, industry-scale manufacturable sensors. We report the design, fabrication, and application of a silicon nitride…