English
Related papers

Related papers: Omni-DNA: A Unified Genomic Foundation Model for C…

200 papers

Many networking tasks now employ deep learning (DL) to solve complex prediction and optimization problems. However, current design philosophy of DL-based algorithms entails intensive engineering overhead due to the manual design of deep…

Networking and Internet Architecture · Computer Science 2024-08-07 Duo Wu , Xianda Wang , Yaqi Qiao , Zhi Wang , Junchen Jiang , Shuguang Cui , Fangxin Wang

In biological tasks, data is rarely plentiful as it is generated from hard-to-gather measurements. Therefore, pre-training foundation models on large quantities of available data and then transfer to low-data downstream tasks is a promising…

Graph foundation models (GFMs) have recently gained significant attention. However, the unique data processing and evaluation setups employed by different studies hinder a deeper understanding of their progress. Additionally, current…

Evolution, the engine behind the survival and growth of life on Earth, operates through the population-based process of reproduction. Inspired by this principle, this paper formally defines a newly emerging problem -- the population-based…

Computation and Language · Computer Science 2025-03-10 Yiqun Zhang , Peng Ye , Xiaocui Yang , Shi Feng , Shufei Zhang , Lei Bai , Wanli Ouyang , Shuyue Hu

RNA's diverse biological functions stem from its structural versatility, yet accurately predicting and designing RNA sequences given a 3D conformation (inverse folding) remains a challenge. Here, I introduce a deep learning framework that…

Quantitative Methods · Quantitative Biology 2026-01-06 Annabelle Yao

Unified large multimodal models (LMMs) have achieved remarkable progress in general-purpose multimodal understanding and generation. However, they still operate under a ``one-size-fits-all'' paradigm and struggle to model user-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yu Zhong , Tianwei Lin , Ruike Zhu , Yuqian Yuan , Haoyu Zheng , Liang Liang , Wenqiao Zhang , Feifei Shao , Haoyuan Li , Wanggui He , Hao Jiang , Yueting Zhuang

Modern large language foundation models (LLM) have now entered the daily lives of millions of users. We ask a natural question whether it is possible to customize LLM for every user or every task. From system and industrial economy…

Machine Learning · Computer Science 2025-04-11 Jianqiao Wangni

Advancements in genomic research such as high-throughput sequencing techniques have driven modern genomic studies into "big data" disciplines. This data explosion is constantly challenging conventional methods used in genomics. In parallel…

Genomics · Quantitative Biology 2023-10-06 Tianwei Yue , Yuanxin Wang , Longxiang Zhang , Chunming Gu , Haoru Xue , Wenping Wang , Qi Lyu , Yujie Dun

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

Computation and Language · Computer Science 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

While recent multimodal large language models (MLLMs) have made impressive strides, they predominantly employ a conventional autoregressive architecture as their backbone, leaving significant room to explore effective and efficient…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Lijiang Li , Zuwei Long , Yunhang Shen , Heting Gao , Haoyu Cao , Xing Sun , Caifeng Shan , Ran He , Chaoyou Fu

Recent advances in large language models (LLMs) have stepped forward the development of multilingual speech and machine translation by its reduced representation errors and incorporated external knowledge. However, both translation tasks…

Computation and Language · Computer Science 2024-05-17 Yuchen Hu , Chen Chen , Chao-Han Huck Yang , Ruizhe Li , Dong Zhang , Zhehuai Chen , Eng Siong Chng

The increasing penetration of distributed energy resources into active distribution networks (ADNs) has made effective ADN dispatch imperative. However, the numerous newly-integrated ADN operators, such as distribution system aggregators,…

Artificial Intelligence · Computer Science 2025-07-30 Xu Yang , Chenhui Lin , Yue Yang , Qi Wang , Haotian Liu , Haizhou Hua , Wenchuan Wu

The integration of Large Language Models (LLMs) with specialized tools presents new opportunities for intelligent automation systems. However, orchestrating multiple LLM-driven agents to tackle complex tasks remains challenging due to…

Artificial Intelligence · Computer Science 2025-03-27 Pengfei Du

Designing functional transition metal complexes (TMCs) faces challenges due to the vast search space of metals and ligands, requiring efficient optimization strategies. Traditional genetic algorithms (GAs) are commonly used, employing…

Chemical Physics · Physics 2024-10-25 Jieyu Lu , Zhangde Song , Qiyuan Zhao , Yuanqi Du , Yirui Cao , Haojun Jia , Chenru Duan

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Xiaofeng Liu , Qianru Zhang , Thibault Marin , Menghua Xia , Chi Liu , Georges El Fakhri , Jinsong Ouyang

Large language models (LLMs) are, by design, inherently capable of multi-task learning: through a unified next-token prediction paradigm, they can naturally address a wide variety of downstream tasks. Prior work in the motion domain has…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Zeyu Ling , Bo Han , Shiyang Li , Jikang Cheng , Hongdeng Shen , Changqing Zou

Recent advances in AI foundation models have significant potential for lightening the clinical workload by mimicking the comprehensive and multi-faceted approaches used by medical professionals. In the field of radiation oncology, the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Kwanyoung Kim , Yujin Oh , Sangjoon Park , Hwa Kyung Byun , Joongyo Lee , Jin Sung Kim , Yong Bae Kim , Jong Chul Ye

Foundation models (FMs) are large-scale deep learning models trained on massive datasets, often using self-supervised learning techniques. These models serve as a versatile base for a wide range of downstream tasks, including those in…

Machine Learning · Computer Science 2025-01-17 Wasif Khan , Seowung Leem , Kyle B. See , Joshua K. Wong , Shaoting Zhang , Ruogu Fang

Feature transformation aims to reconstruct the feature space of raw features to enhance the performance of downstream models. However, the exponential growth in the combinations of features and operations poses a challenge, making it…

Machine Learning · Computer Science 2024-12-19 Nanxu Gong , Chandan K. Reddy , Wangyang Ying , Haifeng Chen , Yanjie Fu