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Photoacoustic (PA) imaging combines the high optical absorption contrast of optical imaging with the deep tissue penetration of ultrasound detection, offering great potential for functional imaging and disease diagnosis. However, current PA…

Optics · Physics 2026-01-29 Daohuai Jiang , Xuanxuan Ye , Hengrong Lan , Xianzeng Zhang , Fei Gao

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

We propose a novel technique of microscopy to overcome the effects of both scattering and limitation of the accessible depth due to the objective working distance. By combining Laser Optical Feedback Imaging (LOFI) with Acoustic Photon…

We demonstrate a new technique in velocity map imaging (VMI) that allows spatial gating of the laser focal overlap region in time resolved pump-probe experiments. This significantly enhances signal-to-noise ratio by eliminating background…

Versatile, sterically accessible imaging systems capable of in vivo rapid volumetric functional and structural imaging deep in the brain continue to be a limiting factor in neuroscience research. Towards overcoming this obstacle, we present…

Neurons and Cognition · Quantitative Biology 2018-05-10 Manish Kumar , Sandeep Kishore , Jordan Nasenbeny , David McLean , Yevgenia Kozorovitskiy

Photoacoustic imaging (PAI) and ultrasound imaging (USI) are important biomedical imaging techniques, due to their unique and complementary advantages in tissue's structure and function visualization. In this Letter, we proposed a coaxial…

Medical Physics · Physics 2024-11-12 Yunhui Jiang , Fan Zhang , Yuwei Zheng , Ruixi Sun , Fei Gao

Femtosecond spectroscopy is an important tool for tracking rapid photoinduced processes in a variety of materials. To spatially map the processes in a sample would substantially expand the capabilities of the method. This is, however,…

Optics · Physics 2019-05-01 Ondřej Denk , Kaibo Zheng , Donatas Zigmantas , Karel Žídek

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. We present an approach for surpassing the acoustic diffraction limit by exploiting temporal fluctuations in the sample absorption…

Optics · Physics 2017-05-31 Thomas Chaigne , Bastien Arnal , Sergey Vilov , Emmanuel Bossy , Ori Katz

Photoacoustic (PA) imaging is an emerging hybrid imaging modality that combines rich optical spectroscopic contrast and high ultrasonic resolution and thus holds tremendous promise for a wide range of pre-clinical and clinical applications.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Mengjie Shi , Tom Vercauteren , Wenfeng Xia

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Mengjie Guo , Hengrong Lan , Changchun Yang , Fei Gao

Ultrasound super-localization microscopy techniques presented in the last few years enable non-invasive imaging of vascular structures at the capillary level by tracking the flow of ultrasound contrast agents (gas microbubbles). However,…

Tissues and Organs · Quantitative Biology 2016-08-10 Avinoam Bar-Zion , Charles Tremblay-Darveau , Oren Solomon , Dan Adam , Yonina C. Eldar

Avalanche phenomena leverage steeply nonlinear dynamics to generate disproportionately high responses from small perturbations and are found in a multitude of events and materials, enabling technologies including optical phase-conjugate…

Single-shot ultrafast optical imaging plays a very important role in the detection of transient scenes, especially in capturing irreversible or stochastic dynamic scenes. To break the limit of time response speed of electronic devices, such…

A photoacoustic (PA) sensor based on higher order acoustic modes is demonstrated. The PA sensor is designed to enhance the gas-detection performance and simultaneously suppress ambient noise sources (e.g. flow noise, electrical noise and…

An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic…

Biological Physics · Physics 2021-08-04 Kevan Bell , Lyazzat Mukhangaliyeva , Layla Khalili , Parsin Haji Reza

Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Hengrong Lan , Juze Zhang , Changchun Yang , Fei Gao

Photoacoustic imaging (PAI) is a novel medical imaging modality that uses the advantages of the spatial resolution of ultrasound imaging and the high contrast of pure optical imaging. Analytical algorithms are usually employed to…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Moein Mozaffarzadeh , Ali Mahloojifar , Mohammadreza Nasiriavanaki , Mahdi Orooji

We theoretically and experimentally investigate the design of an all-optical noiseless magnification and sampling function free from any active gain medium and associated high-power continuous wave pump source. The proposed technique is…

Optics · Physics 2016-11-23 J. Nuno , M. Gilles , M. Guasoni , C. Finot , J. Fatome

Photoinduced carrier dynamics of nanostructures play a crucial role in developing novel functionalities in advanced materials. Optical pump-probe scanning tunneling microscopy (OPP-STM) represents distinctive capabilities of real-space…

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