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Related papers: Spatial-offset pump-probe imaging of nonradiative …

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Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in…

Numerical Analysis · Mathematics 2016-12-21 Simon Arridge , Paul Beard , Marta Betcke , Ben Cox , Nam Huynh , Felix Lucka , Olumide Ogunlade , Edward Zhang

Ultrafast optical pump-probe spectroscopy is a powerful tool to study dynamics in solid materials on femto- and picosecond timescales. In such experiments, a pump pulse induces dynamics inside a sample by impulsive light-matter interaction,…

Label-free optical microscopy through absorption or scattering spectroscopy provides fundamental insights across biology and materials science, yet its sensitivity remains fundamentally limited by photon shot noise. While recent…

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

Non-invasively focusing light into strongly scattering media, such as biological tissue, is highly desirable but challenging. Recently, wavefront shaping technologies guided by ultrasonic encoding or photoacoustic sensing have been…

Optics · Physics 2014-02-05 Puxiang Lai , Lidai Wang , Jian Wei Tay , Lihong V. Wang

Optical pump-probe spectroscopy is a powerful tool to directly probe the carrier dynamics in materials down to sub-femtosecond resolution. To perform such measurement, while keeping the pump induced perturbation to the sample as small as…

Significance: Compressed sensing (CS) uses special measurement designs combined with powerful mathematical algorithms to reduce the amount of data to be collected while maintaining image quality. This is relevant to almost any imaging…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Markus Haltmeier , Matthias Ye , Karoline Felbermayer , Florian Hinterleitner , Peter Burgholzer

Spectroscopic photoacoustic (sPA) imaging uses multiple wavelengths to differentiate chromophores based on their unique optical absorption spectra. This technique has been widely applied in areas such as vascular mapping, tumor detection,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Fangzhou Lin , Shang Gao , Yichuan Tang , Xihan Ma , Ryo Murakami , Ziming Zhang , John D. Obayemi , Winston W. Soboyejo , Haichong K. Zhang

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

Photoacoustic tomography (PAT) enables non-invasive cross-sectional imaging of biological tissues, but it fails to map the spatial variation of speed-of-sound (SOS) within tissues. While SOS is intimately linked to density and elastic…

Medical Physics · Physics 2024-08-27 Yang Wang , Danni Wang , Liting Zhong , Yi Zhou , Qing Wang , Wufan Chen , Li Qi

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

Standard optical pump-probe methods analyze a system's temporal response to a laser pulse within sub-femtoseconds to several nanoseconds, constrained by the optical delay line's length. While resistance is a sensitive detector in various…

Instrumentation and Detectors · Physics 2024-04-26 M. I. Blumenau , A. Yu. Kuntsevich

Super-resolved far-field microscopy has emerged as a powerful tool for investigating the structure of objects with resolution well below the diffraction limit of light. Nearly all super-resolution imaging techniques reported to date rely on…

Snapshot mosaic multispectral imagery acquires an undersampled data cube by acquiring a single spectral measurement per spatial pixel. Sensors which acquire $p$ frequencies, therefore, suffer from severe $1/p$ undersampling of the full data…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Giancarlo A. Antonucci , Simon Vary , David Humphreys , Robert A. Lamb , Jonathan Piper , Jared Tanner

Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

Medical Physics · Physics 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

The combination of microfluidic technology and optical fluids characterization techniques has been recently applied to produce lab-on-a-chip systems. In the present work, bringing together the imaging technique called photoacoustic imaging…

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Ultrasonic sensors are widely used for object detection and localization in underwater and biological settings. The operational range and spatial resolution are inherently limited by sensor sensitivity, in which conventional piezoelectric…

A new method for high-sensitivity subwavelength spectromicroscopy is proposed based on the usage of a spaser (near-field laser) in the form of a scanning probe microscope tip. The high spatial resolution is defined by the tip's curvature,…

Mesoscale and Nanoscale Physics · Physics 2012-08-17 Yuriy E. Lozovik , Igor A. Nechepurenko , Alexander V. Dorofeenko , Alexander A. Pukhov , Eugeniy S. Andrianov

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy