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Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Medical problem-solving demands expert knowledge and intricate reasoning. Recent studies of large language models (LLMs) attempt to ease this complexity by introducing external knowledge verification through retrieval-augmented generation…

Computation and Language · Computer Science 2026-01-19 Yue Huang , Yanyuan Chen , Dexuan Xu , Chenzhuo Zhao , Weihua Yue , Yu Huang

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Mental health remains a challenging problem all over the world, with issues like depression, anxiety becoming increasingly common. Large Language Models (LLMs) have seen a vast application in healthcare, specifically in answering medical…

Computation and Language · Computer Science 2025-02-24 Suraj Racha , Prashant Joshi , Anshika Raman , Nikita Jangid , Mridul Sharma , Ganesh Ramakrishnan , Nirmal Punjabi

The quickly-expanding nature of published medical literature makes it challenging for clinicians and researchers to keep up with and summarize recent, relevant findings in a timely manner. While several closed-source summarization tools…

Information Retrieval · Computer Science 2023-10-26 Alejandro Lozano , Scott L Fleming , Chia-Chun Chiang , Nigam Shah

Spoken question-answering (SQA) systems relying on automatic speech recognition (ASR) often struggle with accurately recognizing medical terminology. To this end, we propose MedSpeak, a novel knowledge graph-aided ASR error correction…

Computation and Language · Computer Science 2026-04-28 Yutong Song , Shiva Shrestha , Chenhan Lyu , Elahe Khatibi , Pengfei Zhang , Honghui Xu , Nikil Dutt , Amir Rahmani

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Large Language Model (LLM)-based systems present new opportunities for autonomous health monitoring in sensor-rich industrial environments. This study explores the potential of LLMs to detect and classify faults directly from sensor data,…

Artificial Intelligence · Computer Science 2025-09-30 Xian Yeow Lee , Lasitha Vidyaratne , Ahmed Farahat , Chetan Gupta

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

In response to the pressing need for advanced clinical problem-solving tools in healthcare, we introduce BooksMed, a novel framework based on a Large Language Model (LLM). BooksMed uniquely emulates human cognitive processes to deliver…

While Medical Large Language Models (MedLLMs) have demonstrated remarkable potential in clinical tasks, their ethical safety remains insufficiently explored. This paper introduces $\textbf{MedEthicsQA}$, a comprehensive benchmark comprising…

Computation and Language · Computer Science 2025-07-01 Jianhui Wei , Zijie Meng , Zikai Xiao , Tianxiang Hu , Yang Feng , Zhijie Zhou , Jian Wu , Zuozhu Liu

Large language models (LLMs) are increasingly used to generate summaries from clinical notes. However, their ability to preserve essential diagnostic information remains underexplored, which could lead to serious risks for patient care.…

Computation and Language · Computer Science 2026-02-20 Heloisa Oss Boll , Antonio Oss Boll , Leticia Puttlitz Boll , Ameen Abu Hanna , Iacer Calixto

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

This paper describes PULSAR, our system submission at the ImageClef 2023 MediQA-Sum task on summarising patient-doctor dialogues into clinical records. The proposed framework relies on domain-specific pre-training, to produce a specialised…

The potential to provide patients with faster information access while allowing medical specialists to concentrate on critical tasks makes medical domain dialog agents appealing. However, the integration of large-language models (LLMs) into…

Computation and Language · Computer Science 2023-08-30 Fabian Lechner , Allison Lahnala , Charles Welch , Lucie Flek

Large Vision-Language Models (LVLMs) show promise for scientific applications, yet open-source models still struggle with Scientific Visual Question Answering (SVQA), namely answering questions about figures from scientific papers. A key…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Yuyi Li , Daoyuan Chen , Zhen Wang , Yutong Lu , Yaliang Li

Large Language Models (LLMs) have emerged as a potential solution to assist digital health development with patient education, commonly medication-related enquires. We trained and validated Med-Pal, a medication domain-specific LLM-chatbot…

High-quality scientific extreme summary (TLDR) facilitates effective science communication. How do large language models (LLMs) perform in generating them? How are LLM-generated summaries different from those written by human experts?…

Computation and Language · Computer Science 2025-12-30 Zhuoqi Lyu , Qing Ke

Large language models (LLMs) have the potential to transform digital healthcare, as evidenced by recent advances in LLM-based virtual doctors. However, current approaches rely on patient's subjective descriptions of symptoms, causing…

Artificial Intelligence · Computer Science 2024-05-22 Bufang Yang , Siyang Jiang , Lilin Xu , Kaiwei Liu , Hai Li , Guoliang Xing , Hongkai Chen , Xiaofan Jiang , Zhenyu Yan