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Related papers: Deep Neural Cellular Potts Models

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The Cellular Potts Model (CPM) is a widely used simulation paradigm for systems of interacting cells that has been used to study scenarios ranging from plant development to morphogenesis, tumour growth and cell migration. Despite their wide…

Tissues and Organs · Quantitative Biology 2023-12-18 Shabaz Sultan , Sapna Devi , Scott N. Mueller , Johannes Textor

The Cellular Potts Model (CPM) is a lattice based modeling technique which is widely used for simulating cellular patterns such as foams or biological tissues. Despite its realism and generality, the standard Monte Carlo algorithm used in…

Soft Condensed Matter · Physics 2016-09-14 Marc Durand , Etienne Guesnet

Simulators driven by deep learning are gaining popularity as a tool for efficiently emulating accurate but expensive numerical simulators. Successful applications of such neural simulators can be found in the domains of physics, chemistry,…

Quantitative Methods · Quantitative Biology 2022-11-04 Koen Minartz , Yoeri Poels , Vlado Menkovski

Biological brains demonstrate complex neural activity, where neural dynamics are critical to how brains process information. Most artificial neural networks ignore the complexity of individual neurons. We challenge that paradigm. By…

Machine Learning · Computer Science 2025-10-06 Luke Darlow , Ciaran Regan , Sebastian Risi , Jeffrey Seely , Llion Jones

The Cellular Potts Model (CPM) has been used for simulating various biological phenomena such as differential adhesion, fruiting body formation of the slime mold Dictyostelium discoideum, angiogenesis, cancer invasion, chondrogenesis in…

Biological Physics · Physics 2009-11-11 Mark Alber , Nan Chen , Tilmann Glimm , Pavel M. Lushnikov

We exhibit a mathematical framework to represent the neural dynamics at cortical level. Our description of neural dynamics with columnar and functional modularity, named fibre bundle representation (FBM) method, is based both on…

Neurons and Cognition · Quantitative Biology 2007-05-23 Myoung Won Cho , Seunghwan Kim

The preliminary analyses on a multiscale model of intestinal crypt dynamics are here presented. The model combines a morphological model, based on the Cellular Potts Model (CPM), and a gene regulatory network model, based on Noisy Random…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Giulio Caravagna , Alex Graudenzi , Marco Antoniotti , Giovanni de Matteis

To computationally investigate the recent experimental finding such that extracellular ATP release caused by exogeneous mechanical forces promote wound closure, we introduce a mathematical model, the Cellular Pots Model (CPM), which is a…

Biological Physics · Physics 2022-09-07 Kenta Odagiri , Hiroshi Fujisaki , Hiroya Takada , Rei Ogawa

In the development of multiscale biological models it is crucial to establish a connection between discrete microscopic or mesoscopic stochastic models and macroscopic continuous descriptions based on cellular density. In this paper a…

Biological Physics · Physics 2009-11-13 Mark Alber , Nan Chen , Pavel M. Lushnikov , Stuart A. Newman

We introduce a scheme for molecular simulations, the Deep Potential Molecular Dynamics (DeePMD) method, based on a many-body potential and interatomic forces generated by a carefully crafted deep neural network trained with ab initio data.…

Computational Physics · Physics 2018-04-11 Linfeng Zhang , Jiequn Han , Han Wang , Roberto Car , Weinan E

In this paper, we hypothesize that the effects of the degree of typicality in natural semantic categories can be generated based on the structure of artificial categories learned with deep learning models. Motivated by the human approach to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-08 Omar Vidal Pino , Erickson Rangel Nascimento , Mario Fernando Montenegro Campos

This paper introduces the Modular Neural Computer (MNC), a memory-augmented neural architecture for exact algorithmic computation on variable-length inputs. The model combines an external associative memory of scalar cells, explicit read…

Machine Learning · Computer Science 2026-03-17 Florin Leon

Most neural models of causality assume static causal graphs, failing to capture the dynamic and sparse nature of physical interactions where causal relationships emerge and dissolve over time. We introduce the Causal Process Framework and…

Machine Learning · Computer Science 2026-04-07 Turan Orujlu , Christian Gumbsch , Martin V. Butz , Charley M Wu

Molecular dynamics simulations use statistical mechanics at the atomistic scale to enable both the elucidation of fundamental mechanisms and the engineering of matter for desired tasks. The behavior of molecular systems at the microscale is…

Computational Physics · Physics 2020-12-25 Wujie Wang , Simon Axelrod , Rafael Gómez-Bombarelli

An adaptive modeling method (AMM) that couples a deep neural network potential and a classical force field is introduced to address the accuracy-efficiency dilemma faced by the molecular simulation community. The AMM simulated system is…

Chemical Physics · Physics 2018-11-14 Linfeng Zhang , Han Wang , Weinan E

Many dynamical systems -- from robots interacting with their surroundings to large-scale multiphysics systems -- involve a number of interacting subsystems. Toward the objective of learning composite models of such systems from data, we…

Machine Learning · Computer Science 2023-05-16 Cyrus Neary , Ufuk Topcu

Concept Bottleneck Models (CBMs) enhance the interpretability of end-to-end neural networks by introducing a layer of concepts and predicting the class label from the concept predictions. A key property of CBMs is that they support…

Machine Learning · Computer Science 2026-03-03 Weixin Chen , Han Zhao

In the fields of computation and neuroscience, much is still unknown about the underlying computations that enable key cognitive functions including learning, memory, abstraction and behavior. This paper proposes a mathematical and…

Artificial Intelligence · Computer Science 2025-01-14 Jeet Singh

Cognitive maps are a proposed concept on how the brain efficiently organizes memories and retrieves context out of them. The entorhinal-hippocampal complex is heavily involved in episodic and relational memory processing, as well as spatial…

Neurons and Cognition · Quantitative Biology 2024-01-04 Paul Stoewer , Achim Schilling , Andreas Maier , Patrick Krauss

Modeling of conservative systems with neural networks is an area of active research. A popular approach is to use Hamiltonian neural networks (HNNs) which rely on the assumptions that a conservative system is described with Hamilton's…

Artificial Intelligence · Computer Science 2024-07-18 Katsiaryna Haitsiukevich , Alexander Ilin
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