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The detection of Alzheimers disease (AD) is considered crucial, as timely intervention can improve patient outcomes. Electroencephalogram (EEG)-based diagnosis has been recognized as a non-invasive, accessible, and cost-effective approach…

Electroencephalography (EEG) has emerged as a cost-effective and efficient tool to support neurologists in the detection of Alzheimer's Disease (AD). However, most existing approaches rely heavily on manual feature engineering or data…

Signal Processing · Electrical Eng. & Systems 2025-08-05 Yihe Wang , Nadia Mammone , Darina Petrovsky , Alexandros T. Tzallas , Francesco C. Morabito , Xiang Zhang

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Electroencephalography (EEG) reflects the brain's functional state, making it a crucial tool for diverse detection applications like seizure detection and sleep stage classification. While deep learning-based approaches have recently shown…

Machine Learning · Computer Science 2025-10-07 Kerui Wu , Ziyue Zhao , Bülent Yener

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, with around 50 million patients worldwide. Accessible and non-invasive methods of diagnosing and characterising AD are therefore urgently required.…

Neurons and Cognition · Quantitative Biology 2021-07-14 Dominik Klepl , Fei He , Min Wu , Matteo De Marco , Daniel J. Blackburn , Ptolemaios Sarrigiannis

Alzheimer's disease (AD) alters brain electrophysiology and disrupts multichannel EEG dynamics, making accurate and clinically useful EEG-based diagnosis increasingly important for screening and disease monitoring. However, many existing…

Machine Learning · Computer Science 2026-02-23 Hairong Chen , Yicheng Feng , Ziyu Jia , Samir Bhatt , Hengguan Huang

Electroencephalography provides a non-invasive window into brain activity, offering valuable insights for neurological research, brain-computer interfaces, and clinical diagnostics. However, the development of robust machine learning models…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Chi-Sheng Chen , Ying-Jung Chen , Aidan Hung-Wen Tsai

Alzheimers disease (AD) is a progressive disorder that affects cognitive brain functions and starts many years before its clinical manifestations. A biomarker that provides a quantitative measure of changes in the brain due to AD in the…

Neurons and Cognition · Quantitative Biology 2022-05-19 Ali H. Al-Nuaimi , Emmanuel Jammeh , Lingfen Sun , Emmanuel Ifeachor

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

While electroencephalography (EEG) has been a popular modality for neural decoding, it often involves task specific acquisition of the EEG data. This poses challenges for the development of a unified pipeline to learn embeddings for various…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Pushapdeep Singh , Jyoti Nigam , Medicherla Vamsi Krishna , Arnav Bhavsar , Aditya Nigam

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

Signal Processing · Electrical Eng. & Systems 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez

Electroencephalography (EEG) is an essential technique for neuroscience research and brain-computer interface (BCI) applications. Recently, large-scale EEG foundation models have been developed, exhibiting robust generalization capabilities…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Zhige Chen , Chengxuan Qin , Wenlong You , Rui Liu , Congying Chu , Rui Yang , Kay Chen Tan , Jibin Wu

Alzheimer's disease (AD) is a prevalent and debilitating neurodegenerative disorder impacting a large aging population. Detecting AD in all its presymptomatic and symptomatic stages is crucial for early intervention and treatment. An active…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Yasmine Mustafa , Tie Luo

Alzheimer's Disease (AD) is a prevalent neurodegenerative condition where early detection is vital. Handwriting, often affected early in AD, offers a non-invasive and cost-effective way to capture subtle motor changes. State-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Changqing Gong , Huafeng Qin , Mounîm A. El-Yacoubi

Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Juan Manuel Fernández Montenegro

Deep learning models for medical image analysis often act as black boxes, seldom aligning with clinical guidelines or explicitly linking decisions to supporting evidence. This is especially critical in Alzheimer's disease (AD), where…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Qiuhui Chen , Xuancheng Yao , Zhenglei Zhou , Xinyue Hu , Yi Hong

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Early diagnosis of Alzheimer's disease (AD) remains a major challenge due to the subtle and temporally irregular progression of structural brain changes in the prodromal stages. Existing deep learning approaches require large longitudinal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Maxx Richard Rahman , Mostafa Hammouda , Wolfgang Maass

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

Machine Learning · Computer Science 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang
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