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Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Machine Learning · Computer Science 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

This paper compares the effectiveness of traditional machine learning methods, encoder-based models, and large language models (LLMs) on the task of detecting depression and anxiety. Five Russian-language datasets were considered, each…

Computation and Language · Computer Science 2025-11-04 Gleb Kuzmin , Petr Strepetov , Maksim Stankevich , Natalia Chudova , Artem Shelmanov , Ivan Smirnov

Reinforcement learning (RL) has recently shown promise in predicting Alzheimer's disease (AD) progression due to its unique ability to model domain knowledge. However, it is not clear which RL algorithms are well-suited for this task.…

We present a systematic study of medical-domain interpretability in Large Language Models (LLMs). We study how the LLMs both represent and process medical knowledge through four different interpretability techniques: (1) UMAP projections of…

Machine Learning · Computer Science 2026-02-24 Razvan Marinescu , Victoria-Elisabeth Gruber , Diego Fajardo

Artificial Intelligence (AI) is increasingly being integrated into scientific research, particularly in the social sciences, where understanding human behavior is critical. Large Language Models (LLMs) have shown promise in replicating…

Computation and Language · Computer Science 2025-06-23 Ziyan Cui , Ning Li , Huaikang Zhou

Systematic reviews are crucial for synthesizing scientific evidence but remain labor-intensive, especially when extracting detailed methodological information. Large language models (LLMs) offer potential for automating methodological…

Computation and Language · Computer Science 2025-10-14 Wenqing Zhang , Trang Nguyen , Elizabeth A. Stuart , Yiqun T. Chen

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

Can large language models introspect, that is, accurately detect perturbations to their own internal states? We systematically investigate this question using activation steering in Meta-Llama-3.1-8B-Instruct. First, we show that the binary…

Artificial Intelligence · Computer Science 2026-03-03 Ely Hahami , Ishaan Sinha , Lavik Jain , Josh Kaplan , Jon Hahami

Depressive and anxiety disorders are widespread, necessitating timely identification and management. Recent advances in Large Language Models (LLMs) offer potential solutions, yet high costs and ethical concerns about training data remain…

Computation and Language · Computer Science 2025-01-28 June M. Liu , Mengxia Gao , Sahand Sabour , Zhuang Chen , Minlie Huang , Tatia M. C. Lee

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

While mechanistic interpretability has developed powerful tools to analyze the internal workings of Large Language Models (LLMs), their complexity has created an accessibility gap, limiting their use to specialists. We address this…

Computation and Language · Computer Science 2026-02-23 Aaron Louis Eidt , Nils Feldhus

Model interpretability is crucial for understanding and trusting the decisions made by complex machine learning models, such as those built with XGBoost. SHAP (SHapley Additive exPlanations) values have become a popular tool for…

Human-Computer Interaction · Computer Science 2026-03-04 Xianlong Zeng , Kewen Zhu

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

Computation and Language · Computer Science 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Large language models (LLMs) have demonstrated unprecedented emergent capabilities, including content generation, translation, and simulation of human behavior. Field experiments, on the other hand, are widely employed in social studies to…

Computers and Society · Computer Science 2025-05-22 Yaoyu Chen , Yuheng Hu , Yingda Lu

Accurate survival prediction in radiotherapy (RT) is critical for optimizing treatment decisions. This study developed and validated the RT-Surv framework, which integrates general-domain, open-source large language models (LLMs) to…

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

This study investigates the effectiveness of Large Language Models (LLMs) in interpreting existing literature through a systematic review of the relationship between Environmental, Social, and Governance (ESG) factors and financial…

Computation and Language · Computer Science 2024-10-29 Aaditya Shah , Shridhar Mehendale , Siddha Kanthi

Over an extensive duration, administrators and clinicians have endeavoured to predict Emergency Department (ED) visits with precision, aiming to optimise resource distribution. Despite the proliferation of diverse AI-driven models tailored…

Machine Learning · Computer Science 2025-11-11 Mehdi Neshat , Michael Phipps , Nikhil Jha , Danial Khojasteh , Michael Tong , Amir Gandomi

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…