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The escalating global mental health crisis, marked by persistent treatment gaps, availability, and a shortage of qualified therapists, positions Large Language Models (LLMs) as a promising avenue for scalable support. While LLMs offer…

In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…

Machine Learning · Computer Science 2025-10-30 Ria Jayanti , Tanish Jain

Background Major depressive disorder (MDD) is a leading cause of global disability, yet current diagnostic approaches often rely on subjective assessments and lack the ability to integrate multimodal clinical information. Large language…

Machine Learning · Computer Science 2025-09-30 Yuyang Sha , Hongxin Pan , Gang Luo , Caijuan Shi , Jing Wang , Kefeng Li

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large language models (LLMs) have garnered significant attention and widespread usage due to their impressive performance in various tasks. However, they are not without their own set of challenges, including issues such as hallucinations,…

Computation and Language · Computer Science 2024-05-08 Duygu Altinok

We present a comprehensive evaluation framework for assessing Large Language Models' (LLMs) capabilities in suicide prevention, focusing on two critical aspects: the Identification of Implicit Suicidal ideation (IIS) and the Provision of…

Computation and Language · Computer Science 2026-01-14 Tong Li , Shu Yang , Junchao Wu , Jiyao Wei , Lijie Hu , Mengdi Li , Derek F. Wong , Joshua R. Oltmanns , Di Wang

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

Large language models (LLMs) are prone to hallucination stemming from misaligned self-awareness, particularly when processing queries exceeding their knowledge boundaries. While existing mitigation strategies employ uncertainty estimation…

Computation and Language · Computer Science 2025-10-10 Hang Zheng , Hongshen Xu , Yuncong Liu , Lu Chen , Pascale Fung , Kai Yu

Major depressive disorder (MDD) impacts more than 300 million people worldwide, highlighting a significant public health issue. However, the uneven distribution of medical resources and the complexity of diagnostic methods have resulted in…

Computation and Language · Computer Science 2025-05-02 Yuyang Sha , Hongxin Pan , Wei Xu , Weiyu Meng , Gang Luo , Xinyu Du , Xiaobing Zhai , Henry H. Y. Tong , Caijuan Shi , Kefeng Li

Adverse Drug Reactions (ADRs) from psychiatric medications are the leading cause of hospitalizations among mental health patients. With healthcare systems and online communities facing limitations in resolving ADR-related issues, Large…

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Computation and Language · Computer Science 2025-02-14 Lena Schmidt , Kaitlyn Hair , Sergio Graziosi , Fiona Campbell , Claudia Kapp , Alireza Khanteymoori , Dawn Craig , Mark Engelbert , James Thomas

Accurate disease prediction is vital for timely intervention, effective treatment, and reducing medical complications. While symbolic AI has been applied in healthcare, its adoption remains limited due to the effort required for…

Artificial Intelligence · Computer Science 2026-01-01 Ioanna Gemou , Evangelos Lamprou

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

The issue of left before treatment complete (LBTC) patients is common in emergency departments (EDs). This issue represents a medico-legal risk and may cause a revenue loss. Thus, understanding the factors that cause patients to leave…

Artificial Intelligence · Computer Science 2022-12-23 Abdulaziz Ahmed , Khalid Y. Aram , Salih Tutun

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

Alzheimer's disease (AD) is the fifth-leading cause of death among Americans aged 65 and older. Screening and early detection of AD and related dementias (ADRD) are critical for timely intervention and for identifying clinical trial…

Artificial Intelligence · Computer Science 2024-05-29 Jiankun Wang , Sumyeong Ahn , Taykhoom Dalal , Xiaodan Zhang , Weishen Pan , Qiannan Zhang , Bin Chen , Hiroko H. Dodge , Fei Wang , Jiayu Zhou

Despite the increasing demand for AI-based mental health monitoring tools, their practical utility for clinicians is limited by the lack of interpretability.The CLPsych 2024 Shared Task (Chim et al., 2024) aims to enhance the…

Computation and Language · Computer Science 2024-02-26 Hyolim Jeon , Dongje Yoo , Daeun Lee , Sejung Son , Seungbae Kim , Jinyoung Han

This study evaluates advanced natural language processing (NLP) techniques to enhance crash data quality by mining crash narratives, using secondary crash identification in Kentucky as a case study. Drawing from 16,656 manually reviewed…

Computation and Language · Computer Science 2025-08-07 Xu Zhang , Mei Chen