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Related papers: MDDM: A Molecular Dynamics Diffusion Model to Pred…

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Diffusion models (DMs) have demonstrated exceptional generative capabilities across various domains, including image, video, and so on. A key factor contributing to their effectiveness is the high quantity and quality of data used during…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Qianlong Xiang , Miao Zhang , Yuzhang Shang , Jianlong Wu , Yan Yan , Liqiang Nie

Probabilistic denoising diffusion models (DDMs) have set a new standard for 2D image generation. Extending DDMs for 3D content creation is an active field of research. Here, we propose TetraDiffusion, a diffusion model that operates on a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Nikolai Kalischek , Torben Peters , Jan D. Wegner , Konrad Schindler

This Letter introduces an approach for precisely designing surface friction properties using a conditional generative machine learning model, specifically a diffusion denoising probabilistic model (DDPM). We created a dataset of synthetic…

Computational Physics · Physics 2024-01-11 Even Marius Nordhagen , Henrik Andersen Sveinsson , Anders Malthe-Sørenssen

MD-GAN is a machine learning-based method that can evolve part of the system at any time step, accelerating the generation of molecular dynamics data. For the accurate prediction of MD-GAN, sufficient information on the dynamics of a part…

Chemical Physics · Physics 2022-02-03 Ryo Kawada , Katsuhiro Endo , Daisuke Yuhara , Kenji Yasuoka

Molecular dynamics (MD) simulation has long been the principal computational tool for exploring protein conformational landscapes and dynamics, but its application is limited by high computational cost. We present ProTDyn, a foundation…

Biological Physics · Physics 2025-10-02 Yikai Liu , Haoyang Zheng , Lining Mao , Yanbin Wang , Ming Chen , Guang Lin

Denoising Diffusion Models (DDMs) have become a popular tool for generating high-quality samples from complex data distributions. These models are able to capture sophisticated patterns and structures in the data, and can generate samples…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Emanuele Aiello , Diego Valsesia , Enrico Magli

We introduce a Cascaded Diffusion Model (Cas-DM) that improves a Denoising Diffusion Probabilistic Model (DDPM) by effectively incorporating additional metric functions in training. Metric functions such as the LPIPS loss have been proven…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Jie An , Zhengyuan Yang , Jianfeng Wang , Linjie Li , Zicheng Liu , Lijuan Wang , Jiebo Luo

Molecular generation and molecular property prediction are both crucial for drug discovery, but they are often developed independently. Inspired by recent studies, which demonstrate that diffusion model, a prominent generative approach, can…

Machine Learning · Computer Science 2025-04-07 Shikun Feng , Yuyan Ni , Yan Lu , Zhi-Ming Ma , Wei-Ying Ma , Yanyan Lan

Denoising diffusion probabilistic models (DDPMs) have emerged as competitive generative models yet brought challenges to efficient sampling. In this paper, we propose novel bilateral denoising diffusion models (BDDMs), which take…

Machine Learning · Computer Science 2021-09-15 Max W. Y. Lam , Jun Wang , Rongjie Huang , Dan Su , Dong Yu

Recent advances in motion diffusion models have substantially improved the realism of human motion synthesis. However, existing approaches either rely on full-sequence diffusion models with bidirectional generation, which limits temporal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Qing Yu , Akihisa Watanabe , Kent Fujiwara

Masked diffusion models (MDMs) have recently emerged as a promising alternative to autoregressive models over discrete domains. MDMs generate sequences in an any-order, parallel fashion, enabling fast inference and strong performance on…

Machine Learning · Computer Science 2025-09-09 Jaeyeon Kim , Lee Cheuk-Kit , Carles Domingo-Enrich , Yilun Du , Sham Kakade , Timothy Ngotiaoco , Sitan Chen , Michael Albergo

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou

In this work, we propose FastDPM, a unified framework for fast sampling in diffusion probabilistic models. FastDPM generalizes previous methods and gives rise to new algorithms with improved sample quality. We systematically investigate the…

Machine Learning · Computer Science 2021-06-25 Zhifeng Kong , Wei Ping

Out-of-distribution detection is crucial to the safe deployment of machine learning systems. Currently, unsupervised out-of-distribution detection is dominated by generative-based approaches that make use of estimates of the likelihood or…

Due to the high complexity and technical requirements of industrial production processes, surface defects will inevitably appear, which seriously affects the quality of products. Although existing lightweight detection networks are highly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Xuyi Yu

Distribution matching is a fixed-length invertible mapping from a uniformly distributed bit sequence to shaped amplitudes and plays an important role in the probabilistic amplitude shaping framework. With conventional constantcomposition…

Signal Processing · Electrical Eng. & Systems 2018-08-13 Tobias Fehenberger , David S. Millar , Toshiaki Koike-Akino , Keisuke Kojima , Kieran Parsons

Part of the success of diffusion models stems from their ability to perform iterative refinement, i.e., repeatedly correcting outputs during generation. However, modern masked discrete diffusion lacks this capability: when a token is…

Machine Learning · Computer Science 2026-02-10 Guanghan Wang , Yair Schiff , Subham Sekhar Sahoo , Volodymyr Kuleshov

Modern successes of diffusion models in learning complex, high-dimensional data distributions are attributed, in part, to their capability to construct diffusion processes with analytic transition kernels and score functions. The…

Machine Learning · Statistics 2024-03-01 Guan-Horng Liu , Tianrong Chen , Evangelos A. Theodorou , Molei Tao

Diffusion models have emerged as powerful generative frameworks by progressively adding noise to data through a forward process and then reversing this process to generate realistic samples. While these models have achieved strong…

Machine Learning · Computer Science 2025-03-04 Xingzhuo Guo , Yu Zhang , Baixu Chen , Haoran Xu , Jianmin Wang , Mingsheng Long

Diffusion models are the de facto approach for generating high-quality images and videos, but learning high-dimensional models remains a formidable task due to computational and optimization challenges. Existing methods often resort to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Jiatao Gu , Shuangfei Zhai , Yizhe Zhang , Josh Susskind , Navdeep Jaitly