English
Related papers

Related papers: MDDM: A Molecular Dynamics Diffusion Model to Pred…

200 papers

We introduce the state-of-the-art deep learning Denoising Diffusion Probabilistic Model (DDPM) as a method to infer the volume or number density of giant molecular clouds (GMCs) from projected mass surface density maps. We adopt…

Astrophysics of Galaxies · Physics 2023-06-28 Duo Xu , Jonathan C. Tan , Chia-Jung Hsu , Ye Zhu

The introduction of diffusion models in anomaly detection has paved the way for more effective and accurate image reconstruction in pathologies. However, the current limitations in controlling noise granularity hinder diffusion models'…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Cosmin I. Bercea , Michael Neumayr , Daniel Rueckert , Julia A. Schnabel

The task of deducing three-dimensional molecular configurations from their two-dimensional graph representations holds paramount importance in the fields of computational chemistry and pharmaceutical development. The rapid advancement of…

Biomolecules · Quantitative Biology 2025-01-09 Bobin Yang , Jie Deng , Zhenghan Chen , Ruoxue Wu

Conventional molecular dynamics (MD) simulation approaches, such as $\textit{ab initio}$ MD (AIMD) and empirical force field MD (EFFMD), face significant trade-offs between physical accuracy and computational efficiency. This work presents…

Disordered Systems and Neural Networks · Physics 2026-05-12 Hongyu Yan , Yong Wei , Minghan Chen , Hanning Chen

A diffusion probabilistic model (DPM), which constructs a forward diffusion process by gradually adding noise to data points and learns the reverse denoising process to generate new samples, has been shown to handle complex data…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Zhengxiong Luo , Dayou Chen , Yingya Zhang , Yan Huang , Liang Wang , Yujun Shen , Deli Zhao , Jingren Zhou , Tieniu Tan

Masked diffusion models (MDMs) have achieved notable progress in modeling discrete data, while their potential in molecular generation remains underexplored. In this work, we explore their potential and introduce the surprising result that…

Machine Learning · Computer Science 2025-09-29 Hyunjin Seo , Taewon Kim , Sihyun Yu , SungSoo Ahn

Diffusion Probabilistic Models (DPMs) have emerged as the de facto approach for high-fidelity image synthesis, operating diffusion processes on continuous VAE latent, which significantly differ from the text generation methods employed by…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Xiaoping Wu , Jie Hu , Xiaoming Wei

Diffusion probabilistic models (DPMs) and their extensions have emerged as competitive generative models yet confront challenges of efficient sampling. We propose a new bilateral denoising diffusion model (BDDM) that parameterizes both the…

Audio and Speech Processing · Electrical Eng. & Systems 2022-03-28 Max W. Y. Lam , Jun Wang , Dan Su , Dong Yu

We present a data-efficient, multiscale framework for predicting the density profiles of confined fluids at the nanoscale. While accurate density estimates require prohibitively long timescales that are inaccessible by ab initio molecular…

Computational Physics · Physics 2025-09-11 Bugra Yalcin , Ishan Nadkarni , Jinu Jeong , Chenxing Liang , Narayana R. Aluru

Generating human motion guided by conditions such as textual descriptions is challenging due to the need for datasets with pairs of high-quality motion and their corresponding conditions. The difficulty increases when aiming for finer…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Pablo Ruiz-Ponce , German Barquero , Cristina Palmero , Sergio Escalera , José García-Rodríguez

The ensemble average of physical properties of molecules is closely related to the distribution of molecular conformations, and sampling such distributions is a fundamental challenge in physics and chemistry. Traditional methods like…

Machine Learning · Computer Science 2025-08-06 Liya Guo , Zun Wang , Chang Liu , Junzhe Li , Pipi Hu , Yi Zhu

Discrete diffusion models form a powerful class of generative models across diverse domains, including text and graphs. However, existing approaches face fundamental limitations. Masked diffusion models suffer from irreversible errors due…

Machine Learning · Computer Science 2026-04-21 Marcel Kollovieh , Sirine Ayadi , Stephan Günnemann

Vision-based motion capture solutions often struggle with occlusions, which result in the loss of critical joint information and hinder accurate 3D motion reconstruction. Other wearable alternatives also suffer from noisy or unstable data,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Junkun Jiang , Jie Chen , Ho Yin Au , Jingyu Xiang

Many scientific and engineering systems exhibit intrinsically multimodal behavior arising from latent regime switching and non-unique physical mechanisms. In such settings, learning the full conditional distribution of admissible outcomes…

Machine Learning · Computer Science 2026-02-12 Jinkyo Han , Bahador Bahmani

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

Masked diffusion models (MDMs) generate discrete sequences by iterative denoising under an absorbing masking process. In standard masked diffusion, if a token remains masked after a reverse update, the model discards its clean-state…

Machine Learning · Computer Science 2026-05-01 Michael Cardei , Huu Binh Ta , Ferdinando Fioretto

Diffusion models (DM) can gradually learn to remove noise, which have been widely used in artificial intelligence generated content (AIGC) in recent years. The property of DM for removing noise leads us to wonder whether DM can be applied…

Information Theory · Computer Science 2023-05-17 Tong Wu , Zhiyong Chen , Dazhi He , Liang Qian , Yin Xu , Meixia Tao , Wenjun Zhang

Diffusion models (DM) can gradually learn to remove noise, which have been widely used in artificial intelligence generated content (AIGC) in recent years. The property of DM for eliminating noise leads us to wonder whether DM can be…

Information Theory · Computer Science 2023-09-19 Tong Wu , Zhiyong Chen , Dazhi He , Liang Qian , Yin Xu , Meixia Tao , Wenjun Zhang

We present a probabilistic model for point cloud generation, which is fundamental for various 3D vision tasks such as shape completion, upsampling, synthesis and data augmentation. Inspired by the diffusion process in non-equilibrium…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Shitong Luo , Wei Hu

Diffusion models have shown promise in forecasting future data from multivariate time series. However, few existing methods account for recurring structures, or patterns, that appear within the data. We present Pattern-Guided Diffusion…

Machine Learning · Computer Science 2025-12-17 Vivian Lin , Kuk Jin Jang , Wenwen Si , Insup Lee