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Early cancer detection is crucial for prognosis, but many cancer types lack large labelled datasets required for developing deep learning models. This paper investigates self-supervised learning (SSL) as an alternative to the standard…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Hamish Haggerty , Rohitash Chandra

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Whole-slide images (WSIs) are critical for cancer diagnosis due to their ultra-high resolution and rich semantic content. However, their massive size and the limited availability of fine-grained annotations pose substantial challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Daoxi Cao , Hangbei Cheng , Yijin Li , Ruolin Zhou , Xuehan Zhang , Xinyi Li , Binwei Li , Xuancheng Gu , Jianan Zhang , Xueyu Liu , Yongfei Wu

With the wealth of medical image data, efficient curation is essential. Assigning the sequence type to magnetic resonance images is necessary for scientific studies and artificial intelligence-based analysis. However, incomplete or missing…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Deepa Krishnaswamy , Bálint Kovács , Stefan Denner , Steve Pieper , David Clunie , Christopher P. Bridge , Tina Kapur , Klaus H. Maier-Hein , Andrey Fedorov

Due to the recent advancements in machine vision, digital pathology has gained significant attention. Histopathology images are distinctly rich in visual information. The tissue glass slide images are utilized for disease diagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Danial Maleki , Mehdi Afshari , Morteza Babaie , H. R. Tizhoosh

In this paper, we studied extensively on different deep learning based methods to detect melanoma and skin lesion cancers. Melanoma, a form of malignant skin cancer is very threatening to health. Proper diagnosis of melanoma at an earlier…

Computer Vision and Pattern Recognition · Computer Science 2019-01-31 Md Ashraful Alam Milton

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Despite the rapid progress in self-supervised learning (SSL), end-to-end fine-tuning still remains the dominant fine-tuning strategy for medical imaging analysis. However, it remains unclear whether this approach is truly optimal for…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Muhammad Osama Khan , Yi Fang

Prostate cancer (Pca) continues to be a leading cause of cancer-related mortality in men, and the limitations in precision of traditional diagnostic methods such as the Digital Rectal Exam (DRE), Prostate-Specific Antigen (PSA) testing, and…

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Self-supervised learning (SSL) is a machine learning approach where the data itself provides supervision, eliminating the need for external labels. The model is forced to learn about the data structure or context by solving a pretext task.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Markus Marks , Manuel Knott , Neehar Kondapaneni , Elijah Cole , Thijs Defraeye , Fernando Perez-Cruz , Pietro Perona

Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Self-supervised learning (SSL) has emerged as a key technique for training networks that can generalize well to diverse tasks without task-specific supervision. This property makes SSL desirable for computational pathology, the study of…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Eric Zimmermann , Neil Tenenholtz , James Hall , George Shaikovski , Michal Zelechowski , Adam Casson , Fausto Milletari , Julian Viret , Eugene Vorontsov , Siqi Liu , Kristen Severson

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Deep learning (DL) has proven highly effective for ultrasound-based computer-aided diagnosis (CAD) of breast cancers. In an automaticCAD system, lesion detection is critical for the following diagnosis. However, existing DL-based methods…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Jian Wang , Liang Qiao , Shichong Zhou , Jin Zhou , Jun Wang , Juncheng Li , Shihui Ying , Cai Chang , Jun Shi

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Various convolutional neural network (CNN) based concepts have been introduced for the prostate's automatic segmentation and its coarse subdivision into transition zone (TZ) and peripheral zone (PZ). However, when targeting a fine-grained…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Anneke Meyer , Suhita Ghosh , Daniel Schindele , Martin Schostak , Sebastian Stober , Christian Hansen , Marko Rak

Self supervised learning (SSL) is a machine learning paradigm where models learn to understand the underlying structure of data without explicit supervision from labeled samples. The acquired representations from SSL have demonstrated…

Machine Learning · Computer Science 2025-12-11 Yunshan Duan , Sinead Williamson

Current histopathological grading of prostate cancer relies primarily on glandular architecture, largely overlooking the tumor microenvironment. Here, we present PROTAS, a deep learning framework that quantifies reactive stroma (RS) in…

Masked Image Modelling (MIM) has been shown to be an efficient self-supervised learning (SSL) pre-training paradigm when paired with transformer architectures and in the presence of a large amount of unlabelled natural images. The…

Computer Vision and Pattern Recognition · Computer Science 2023-01-02 Alvaro Fernandez-Quilez , Christoffer Gabrielsen Andersen , Trygve Eftestøl , Svein Reidar Kjosavik , Ketil Oppedal