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Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Within medical imaging, manual curation of sufficient well-labeled samples is cost, time and scale-prohibitive. To improve the representativeness of the training dataset, for the first time, we present an approach to utilize large amounts…

Computer Vision and Pattern Recognition · Computer Science 2019-06-03 Fernando Navarro , Sailesh Conjeti , Federico Tombari , Nassir Navab

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

The image reconstruction process in medical imaging can be treated as solving an inverse problem. The inverse problem is usually solved using time-consuming iterative algorithms with sparsity or other constraints. Recently, deep neural…

Medical Physics · Physics 2021-10-29 Jingke Zhang , Qiong He , Congzhi Wang , Hongen Liao , Jianwen Luo

Weakly Supervised Semantic Segmentation (WSSS) is a challenging task aiming to learn the segmentation labels from class-level labels. In the literature, exploiting the information obtained from Class Activation Maps (CAMs) is widely used…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Cenk Bircanoglu , Nafiz Arica

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Purpose: Demonstrating and assessing self-supervised machine learning fitting of the VERDICT (Vascular, Extracellular and Restricted DIffusion for Cytometry in Tumours) model for prostate. Methods: We derive a self-supervised neural network…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Snigdha Sen , Saurabh Singh , Hayley Pye , Caroline M. Moore , Hayley Whitaker , Shonit Punwani , David Atkinson , Eleftheria Panagiotaki , Paddy J. Slator

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

Rectal cancer is one of the most common diseases and a major cause of mortality. For deciding rectal cancer treatment plans, T-staging is important. However, evaluating the index from preoperative MRI images requires high radiologists'…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Saeko Sasuga , Akira Kudo , Yoshiro Kitamura , Satoshi Iizuka , Edgar Simo-Serra , Atsushi Hamabe , Masayuki Ishii , Ichiro Takemasa

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Recent advances in robust semi-supervised learning (SSL) typically filter out-of-distribution (OOD) information at the sample level. We argue that an overlooked problem of robust SSL is its corrupted information on semantic level,…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Yu Wang , Pengchong Qiao , Chang Liu , Guoli Song , Xiawu Zheng , Jie Chen

In the last years, the weakly supervised paradigm of multiple instance learning (MIL) has become very popular in many different areas. A paradigmatic example is computational pathology, where the lack of patch-level labels for whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Pablo Morales-Álvarez , Arne Schmidt , José Miguel Hernández-Lobato , Rafael Molina

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Self-supervised learning (SSL) for RGB images has achieved significant success, yet there is still limited research on SSL for infrared images, primarily due to three prominent challenges: 1) the lack of a suitable large-scale infrared…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Tao Zhang , Kun Ding , Jinyong Wen , Yu Xiong , Zeyu Zhang , Shiming Xiang , Chunhong Pan

The increasing prevalence of prostate cancer has led to the widespread adoption of Robotic-Assisted Surgery (RAS) as a treatment option. Sentinel lymph node biopsy (SLNB) is a crucial component of prostate cancer surgery and requires…

Robotics · Computer Science 2023-04-28 Kaizhong Deng , Baoru Huang , Daniel S. Elson

Self-supervised learning (SSL) has emerged as a powerful strategy for representation learning under limited annotation regimes, yet its effectiveness remains highly sensitive to many factors, especially the nature of the target task. In…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jorge Quesada , Ghassan AlRegib

Correctly classifying brain tumors is imperative to the prompt and accurate treatment of a patient. While several classification algorithms based on classical image processing or deep learning methods have been proposed to rapidly classify…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Minh-Hao Van , Alycia N. Carey , Xintao Wu

Using deep learning models to diagnose cancer from histology data presents several challenges. Cancer grading and localization of regions of interest (ROIs) in these images normally relies on both image- and pixel-level labels, the latter…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Jérôme Rony , Soufiane Belharbi , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger
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