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Related papers: OCSU: Optical Chemical Structure Understanding for…

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SMILES is a linear representation of chemical structures which encodes the connection table, and the stereochemistry of a molecule as a line of text with a grammar structure denoting atoms, bonds, rings and chains, and this information can…

Machine Learning · Computer Science 2018-12-03 Arindam Paul , Dipendra Jha , Reda Al-Bahrani , Wei-keng Liao , Alok Choudhary , Ankit Agrawal

The problem of accelerating drug discovery relies heavily on automatic tools to optimize precursor molecules to afford them with better biochemical properties. Our work in this paper substantially extends prior state-of-the-art on…

Chemical Physics · Physics 2019-10-22 Wengong Jin , Regina Barzilay , Tommi Jaakkola

Comprehensive and confident identifications of metabolites and other chemicals in complex samples will revolutionize our understanding of the role these chemically diverse molecules play in biological systems. Despite recent advances,…

The automated extraction of chemical structures and their corresponding bioactivity data is essential for accelerating drug discovery and enabling data-driven research. Current optical chemical structure recognition tools lack the…

Quantitative Methods · Quantitative Biology 2026-03-04 Zhe Wang , Fangtian Fu , Wei Zhang , Lige Yan , Nan Li , Wenxia Deng , Yan Meng , Jianping Wu , Hui Wu , Wenting Wu , Gang Xu , Xiang Li , Si Chen

Optical character recognition (OCR) is a widely used pattern recognition application in numerous domains. There are several feature-rich, general-purpose OCR solutions available for consumers, which can provide moderate to excellent…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Ayantha Randika , Nilanjan Ray , Xiao Xiao , Allegra Latimer

Recognizing multiple objects in an image is challenging due to occlusions, and becomes even more so when the objects are small. While promising, existing multi-label image recognition models do not explicitly learn context-based…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Hasib Zunair , A. Ben Hamza

Most multilingual vision-and-language (V&L) research aims to accomplish multilingual and multimodal capabilities within one model. However, the scarcity of multilingual captions for images has hindered the development. To overcome this…

Computation and Language · Computer Science 2024-02-06 Guojun Wu

Vision-Language Models (VLMs) have demonstrated remarkable performance across a variety of real-world tasks. However, existing VLMs typically process visual information by serializing images, a method that diverges significantly from the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yueyan Li , Chenggong Zhao , Zeyuan Zang , Caixia Yuan , Xiaojie Wang

In order to define the process of restrosynthesis of a new organic molecule, it is often necessary to be able to draw inspiration from that of a molecule similar to the target one of which we know such a process. To compute such a…

Data Structures and Algorithms · Computer Science 2018-07-13 Stéfi Nouleho , Dominique Barth , Franck Quessette , Marc-Antoine Weisser , Dimitri Watel , Olivier David

Understanding document images (e.g., invoices) is a core but challenging task since it requires complex functions such as reading text and a holistic understanding of the document. Current Visual Document Understanding (VDU) methods…

Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Khiem Le , Zhichun Guo , Kaiwen Dong , Xiaobao Huang , Bozhao Nan , Roshni Iyer , Xiangliang Zhang , Olaf Wiest , Wei Wang , Ting Hua , Nitesh V. Chawla

Conventional optical character recognition (OCR) techniques segmented each character and then recognized. This made them prone to error in character segmentation, and devoid of context to exploit language models. Advances in sequence to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Shashank Vempati , Nishit Anand , Gaurav Talebailkar , Arpan Garai , Chetan Arora

While Vision-Language Models (VLMs) have demonstrated significant potential in chemical visual understanding, current models are predominantly optimized for direct visual question-answering tasks. This paradigm often results in "black-box"…

Computation and Language · Computer Science 2026-04-09 Xuanle Zhao , Xinyuan Cai , Xiang Cheng , Xiuyi Chen , Bo Xu

Multimodal large language models (MLLMs) have recently achieved impressive general-purpose vision-language capabilities through visual instruction tuning. However, current MLLMs primarily focus on image-level or box-level understanding,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Yuqian Yuan , Wentong Li , Jian Liu , Dongqi Tang , Xinjie Luo , Chi Qin , Lei Zhang , Jianke Zhu

This study explores three approaches to processing table data in scientific papers to enhance extractive question answering and develop a software tool for the systematic review process. The methods evaluated include: (1) Optical Character…

Information Retrieval · Computer Science 2025-08-27 Dongyoun Kim , Hyung-do Choi , Youngsun Jang , John Kim

Recently, Vision-Language Pre-training (VLP) techniques have greatly benefited various vision-language tasks by jointly learning visual and textual representations, which intuitively helps in Optical Character Recognition (OCR) tasks due to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Chuhui Xue , Wenqing Zhang , Yu Hao , Shijian Lu , Philip Torr , Song Bai

Multimodal IR, spanning text corpus, knowledge graph and images, called outside knowledge visual question answering (OKVQA), is of much recent interest. However, the popular data set has serious limitations. A surprisingly large fraction of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Aman Jain , Mayank Kothyari , Vishwajeet Kumar , Preethi Jyothi , Ganesh Ramakrishnan , Soumen Chakrabarti

Optical Character Recognition (OCR) has many real world applications. The existing methods normally detect where the characters are, and then recognize the character for each detected location. Thus the accuracy of characters recognition is…

Computer Vision and Pattern Recognition · Computer Science 2020-12-04 Baohua Sun , Michael Lin , Hao Sha , Lin Yang

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

In recent years, general visual foundation models (VFMs) have witnessed increasing adoption, particularly as image encoders for popular multi-modal large language models (MLLMs). However, without semantically fine-grained supervision, these…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Tongkun Guan , Zining Wang , Pei Fu , Zhengtao Guo , Wei Shen , Kai Zhou , Tiezhu Yue , Chen Duan , Hao Sun , Qianyi Jiang , Junfeng Luo , Xiaokang Yang