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While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

We present ImageBind, an approach to learn a joint embedding across six different modalities - images, text, audio, depth, thermal, and IMU data. We show that all combinations of paired data are not necessary to train such a joint…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Rohit Girdhar , Alaaeldin El-Nouby , Zhuang Liu , Mannat Singh , Kalyan Vasudev Alwala , Armand Joulin , Ishan Misra

Multimodal models have demonstrated powerful capabilities in complex tasks requiring multimodal alignment, including zero-shot classification and cross-modal retrieval. However, existing models typically rely on millions of paired…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Fabian Gröger , Shuo Wen , Huyen Le , Maria Brbić

Contrastive Language-Image Pre-training (CLIP) has been shown to learn visual representations with great transferability, which achieves promising accuracy for zero-shot classification. To further improve its downstream performance,…

Computer Vision and Pattern Recognition · Computer Science 2022-12-20 Ziyu Guo , Renrui Zhang , Longtian Qiu , Xianzheng Ma , Xupeng Miao , Xuming He , Bin Cui

In the era of foundation models, CLIP has emerged as a powerful tool for aligning text & visual modalities into a common embedding space. However, the alignment objective used to train CLIP often results in subpar visual features for…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Mohamed Fazli Imam , Rufael Fedaku Marew , Jameel Hassan , Mustansar Fiaz , Alham Fikri Aji , Hisham Cholakkal

CLIP (Contrastive Language-Image Pre-training) uses contrastive learning from noise image-text pairs to excel at recognizing a wide array of candidates, yet its focus on broad associations hinders the precision in distinguishing subtle…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Ziyu Liu , Zeyi Sun , Yuhang Zang , Wei Li , Pan Zhang , Xiaoyi Dong , Yuanjun Xiong , Dahua Lin , Jiaqi Wang

Self-supervised models trained with a contrastive loss such as CLIP have shown to be very powerful in zero-shot classification settings. However, to be used as a zero-shot classifier these models require the user to provide new captions…

Machine Learning · Computer Science 2022-10-31 Bhawesh Kumar , Anil Palepu , Rudraksh Tuwani , Andrew Beam

Multi-label classification is an essential task utilized in a wide variety of real-world applications. Multi-label zero-shot learning is a method for classifying images into multiple unseen categories for which no training data is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Muhammad Ali , Salman Khan

Medical image segmentation of anatomical structures and pathology is crucial in modern clinical diagnosis, disease study, and treatment planning. To date, great progress has been made in deep learning-based segmentation techniques, but most…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Medical image retrieval is essential for clinical decision-making and translational research, relying on discriminative visual representations. Yet, current methods remain fragmented, relying on separate architectures and training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Che Liu , Zheng Jiang , Chengyu Fang , Heng Guo , Yan-Jie Zhou , Jiaqi Qu , Le Lu , Minfeng Xu

In this paper, we introduce a novel regularization scheme on contrastive language-image pre-trained (CLIP) medical vision models. Our approach is based on the observation that on many medical imaging tasks text tokens should only describe a…

Machine Learning · Computer Science 2023-03-01 Anil Palepu , Andrew L. Beam

While Contrastive Language-Image Pretraining (CLIP) excels at zero-shot tasks by aligning image and text embeddings, its performance in few-shot classification is hindered by a critical limitation: intra-modal misalignment. This issue,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Christoph Timmermann , Hyunse Lee , Woojin Lee

Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Mehmet Yigit Avci , Pedro Borges , Virginia Fernandez , Paul Wright , Mehmet Yigitsoy , Sebastien Ourselin , Jorge Cardoso

Domain shift presents a significant challenge in applying Deep Learning to the segmentation of 3D medical images from sources like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). Although numerous Domain Adaptation methods…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Boris Shirokikh , Anvar Kurmukov , Mariia Donskova , Valentin Samokhin , Mikhail Belyaev , Ivan Oseledets

Medical image classification plays a crucial role in clinical decision-making, yet most models are constrained to a fixed set of predefined classes, limiting their adaptability to new conditions. Contrastive Language-Image Pretraining…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Stefan Denner , Markus Bujotzek , Dimitrios Bounias , David Zimmerer , Raphael Stock , Klaus Maier-Hein

CLIP is a widely used foundational vision-language model that is used for zero-shot image recognition and other image-text alignment tasks. We demonstrate that CLIP is vulnerable to change in image quality under compression. This surprising…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Cangxiong Chen , Vinay P. Namboodiri , Julian Padget

Zero-shot anomaly detection (ZSAD) offers potential for identifying anomalies in medical imaging without task-specific training. In this paper, we evaluate CLIP-based models, originally developed for industrial tasks, on brain tumor…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Aldo Marzullo , Marta Bianca Maria Ranzini

Zero-shot medical image classification is a critical process in real-world scenarios where we have limited access to all possible diseases or large-scale annotated data. It involves computing similarity scores between a query medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Jiaxiang Liu , Tianxiang Hu , Yan Zhang , Xiaotang Gai , Yang Feng , Zuozhu Liu

Foundation models like CLIP and SAM have advanced computer vision and medical imaging via low-shot transfer learning, aiding CADD with limited data. However, their deployment faces two key challenges. \textit{distribution shift} where…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Behraj Khan , Tahir Qasim Syed , Nouman M. Durrani , Bilal Naseem , Shabir Ahmad , Rizwan Qureshi

The prowess that makes few-shot learning desirable in medical image analysis is the efficient use of the support image data, which are labelled to classify or segment new classes, a task that otherwise requires substantially more training…