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Recently, the dual-phase grating based X-ray differential phase contrast imaging technique has shown better radiation dose efficiency performance than the Talbot-Lau system. In this paper, we provide a theoretical analyses framework derived…

X-ray interferometry is an emerging imaging modality with a wide variety of potential clinical applications, including lung and breast imaging, as well as in non-destructive testing, such as additive manufacturing and porosimetry. A grating…

X-ray interferometry is an emerging imaging modality with a wide variety of potential clinical applications, including lung imaging. A grating interferometer uses a diffraction grating to produce a periodic interference pattern and measures…

X-ray Talbot-Lau interferometer has been used most widely to perform X-ray phase-contrast imaging with a conventional low-brilliance X-ray source, it yields high-sensitivity phase and dark-field images of sample producing low absorption…

Optics · Physics 2015-04-21 Shenghao Wang , Renfang Hu , Zhili Wang , Kun Gao , Kai Zhang , Atsushi Momose , Ziyu Wu

Grating interferometry is a promising diagnostic technique that enables simultaneous acquisition of three complementary, synergistic X-ray images: transmission, differential phase, and dark-field. Its key advantage over other setups is its…

X-ray Talbot-Lau interferometer has been used widely to conduct phase contrast imaging with a conventional low-brilliance x-ray source. Typically, in this technique, background correction has to be performed in order to obtain the pure…

X-ray grating interferometry allows for the simultaneous acquisition of attenuation, differential-phase contrast, and dark-field images, resulting from X-ray attenuation, refraction, and small-angle scattering, respectively. The modulated…

X-ray grating interferometry is an excellent technique for X-ray phase contrast imaging and X-ray wavefront sensing with applications in materials science, biology and medical diagnosis. Among other requirements, the method depends on the…

Currently, dual-energy X-ray phase contrast imaging is usually conducted with an X-ray Talbot-Lau interferometer. However, in this system, the two adopted energy spectra have to be chosen carefully in order to match well with the phase…

Medical Physics · Physics 2019-11-22 Shenghao Wang , Guibin Zan , Qiuping Wang , Shijie Liu

Grating interferometer is a state of art x-ray imaging approach, which can simultaneously acquire information of x-ray attenuation, phase shift, and small angle scattering. This approach is very sensitive to micro-structural variation and…

Medical Physics · Physics 2015-09-21 Wenxiang Cong , Yan Xi , Ge Wang

Interferometry provides one of the possible routes to ultra-high angular resolution for X-ray and gamma-ray astronomy. Sub-micro-arc-second angular resolution, necessary to achieve objectives such as imaging the regions around the event…

Instrumentation and Methods for Astrophysics · Physics 2009-07-31 G. K. Skinner , J. F. Krizmanic

Dark-field imaging based on grating interferometry is an emerging X-ray modality in medical imaging, which is particularly capable of providing complementary diagnostic information by visualizing the microstructural properties of lung…

Medical Physics · Physics 2026-05-29 Longchao Men , Peiyuan Guo , Jincheng Lu , Yan Xu , Hongxia Yin , Zhenchang Wang , Li Zhang , Zhentian Wang

In this work, a general theoretical framework is presented to explain the formation of the phase signal in an X-ray microscope integrated with a grating interferometer, which simultaneously enables the high spatial resolution imaging and…

Optics · Physics 2022-09-28 Jiecheng Yang , Yongshuai Ge , Dong Liang , Hairong Zheng

Medical differential phase contrast x-ray imaging (DPCI) promises improved soft-tissue contrast at lower x-ray dose. The dose strongly depends on both the angular sensitivity and on the visibility of a grating-based Talbot-Lau…

Medical Physics · Physics 2016-03-23 Oliver Preusche

As a multi-contrast X-ray computed tomography (CT) imaging system, the grating-based Talbot-Lau interferometer is able to generate the absorption contrast and differential phase contrast (DPC) images concurrently. However, experiments found…

Medical Physics · Physics 2024-04-16 Yuhang Tan , Jiecheng Yang , Hairong Zheng , Dong Liang , Peiping Zhu , Yongshuai Ge

The diffraction contrast modalities accessible by X-ray grating interferometers are not imaged directly but have to be inferred from sine like signal variations occurring in a series of images acquired at varying relative positions of the…

Instrumentation and Detectors · Physics 2021-02-01 Jonas Dittmann , Andreas Balles , Simon Zabler

Fabrication of X-ray gratings has surged in the last two decades thanks to their vast employment in X-ray Phase Contrast Imaging, an imaging technique able to boost X-ray sensitivity to detect otherwise invisible details. These high aspect…

Phase-wrapping artifacts, statistical image noise and the need for a minimum amount of phase steps per projection limit the practicability of x-ray grating based phase-contrast tomography, when using filtered back projection reconstruction.…

Recently, X-ray interferometers with more than one phase grating have been developed for differential phase contrast (DPC) imaging. In this study, a novel framework is developed to predict such interferometers' angular sensitivity responses…

Instrumentation and Detectors · Physics 2020-06-25 Jianwei Chen , Jiecheng Yang , Peiping Zhu , Ting Su , Huitao Zhang , Hairong Zheng , Dong Liang , Yongshuai Ge

For a century, clinical X-ray imaging has visualised only the attenuation properties of tissue, which fundamentally limits the contrast, particularly in soft tissues like the breast. Imaging based on refraction can overcome this limitation,…

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