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Imaging with hard x-rays is an invaluable tool in medicine, biology, materials science, and cultural heritage. Propagation-based x-ray phase-contrast imaging and tomography have been mostly used to resolve micrometer-scale structures inside…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Margie P. Olbinado , David M. Paganin , Yin Cheng , Alexander Rack

Based on phase retrieval, lensless coherent imaging and in particular holography offers quantitative phase and amplitude images. This is of particular importance for spectral ranges where suitable lenses are challenging, such as for hard…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Simon Huhn , Leon Merten Lohse , Jens Lucht , Tim Salditt

Knowledge gained through X-ray crystallography fostered structural determination of materials and greatly facilitated the development of modern science and technology in the past century. Atomic details of sample structures is achievable by…

Optics · Physics 2016-09-14 Hong Yu , Ronghua Lu , Shensheng Han , Honglan Xie , Guohao Du , Tiqiao Xiao , Daming Zhu

X-ray phase-contrast imaging has experienced rapid development over the last few decades, and in this technology, the phase modulation strategy of phase-stepping is used most widely to measure the sample's phase signal. However, because of…

Medical Physics · Physics 2017-12-06 Faiz Wali , Shenghao Wang , Huajie Han , Kun Gao , Zhao Wu , Peiping Zhu , Yangchao Tiana

X-ray imaging has conventionally relied upon attenuation to provide contrast. In recent years, two complementary modalities have been added; phase contrast and dark-field x-ray imaging, capturing weakly attenuating and sub-pixel sample…

Optics · Physics 2021-11-16 Kaye S. Morgan , David M. Paganin

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

Instrumentation and Detectors · Physics 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

The low-density imaging performance of a zone plate based nano-resolution hard X-ray computed tomography (CT) system can be significantly improved by incorporating a grating-based Lau interferometer. Due to the diffraction, however, the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-16 Xuebao Cai , Yuhang Tan , Ting Su , Dong Liang , Hairong Zheng , Jinyou Xu , Peiping Zhu , Yongshuai Ge

Dark-field radiography is a novel X-ray imaging modality that enables complementary diagnostic information by visualizing the microstructural properties of lung tissue. Implemented via a Talbot-Lau interferometer integrated into a…

This paper presents a super-resolution method based on gradient-based adaptive interpolation. In this method, in addition to considering the distance between the interpolated pixel and the neighboring valid pixel, the interpolation…

Multimedia · Computer Science 2009-03-25 Jinyu Chu , Ju Liu , Jianping Qiao , Xiaoling Wang , Yujun Li

We present a multi-aperture analyser set-up for performing X-ray phase contrast imaging in planar and three-dimensional modalities. A multi-slice representation of the sample is used to establish a quantitative relation between projection…

Instrumentation and Detectors · Physics 2017-06-21 M. Endrizzi , F. A. Vittoria , L. Rigon , D. Dreossi , A. Olivo

Future NASA X-ray spectroscopy missions will require high throughput, high resolution grating spectrometers. Off-plane reflection gratings are capable of meeting the performance requirements needed to realize the scientific goals of these…

This study investigates the application of Super-Resolution techniques in holographic microscopy to enhance quantitative phase imaging. An off-axis Mach-Zehnder interferometric setup was employed to capture interferograms. The study…

Ptychography has become prominent at synchrotron facilities worldwide for characterizing biological and material specimens' topological structures and properties at the nanometer or atomic scale, due to its lens - less, highly quantitative…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Tao Liu , Bingyang Wang , JiangTao Zhao , Maik Kahnt , Fucai Zhang

X-ray microtomography is a versatile tool allowing the measurement of the 3D structure of optically thick samples. As a non-destructive technique, it is readily adapted to 4D imaging, where a sample can be monitored over time, and…

Instrumentation and Detectors · Physics 2025-12-17 Harry Allan , Tom Partridge , Joseph Jacob , Marco Endrizzi

We propose a high resolution spatial diagnostic method via inserting a millimeter-gap grating into the collimated terahertz beam to monitor the minute variation of the terahertz beam in strong-field terahertz sources, which is difficult to…

Thin film interferometry is a powerful technique for non-invasively measuring liquid film thickness with applications in ophthalmology, but its clinical translation is hindered by the challenges in reconstructing thickness profiles from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Gautam A. Viruthagiri , Arnuv Tandon , Gerald G. Fuller , Vinny Chandran Suja

Terahertz imaging holds great potential for non-destructive material inspection, but practical implementation has been limited by resolution constraints. In this study, we present a single-pixel THz imaging system based on a confocal…

An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking…

Performing X-ray computed tomography (CT) examinations with less radiation has recently received increasing interest: in medical imaging this means less (potentially harmful) radiation for the patient; in non-destructive testing of…

Medical Physics · Physics 2018-09-25 Dragos Trinca , Eduard Libin

We provide the first demonstration that a neutron far-field interferometer can be employed to measure the microstructure of a sample. The interferometer is based on the moir\'e pattern of two phase modulating gratings which was previously…