Related papers: Hypergraph Representations of scRNA-seq Data for I…
The increasing capacity of high-throughput genomic technologies for generating time-course data has stimulated a rich debate on the most appropriate methods to highlight crucial aspects of data structure. In this work, we address the…
Graph neural networks (GNNs) have demonstrated promising performance across various chemistry-related tasks. However, conventional graphs only model the pairwise connectivity in molecules, failing to adequately represent higher-order…
Rapidly growing public gene expression databases contain a wealth of data for building an unprecedentedly detailed picture of human biology and disease. This data comes from many diverse measurement platforms that make integrating it all…
Heterogeneous graph neural networks (HGNNs) have demonstrated strong capability in modeling complex semantics across multi-type nodes and relations. However, their scalability to large-scale graphs remains challenging due to structural…
Technology convergence integrates distinct domains to create novel combinations, driving radical innovation that reshapes markets and industries. However, most approaches rely on pairwise networks that cannot capture multi-technology…
Hypergraphs are a common model for multiway relationships in data, and hypergraph semi-supervised learning is the problem of assigning labels to all nodes in a hypergraph, given labels on just a few nodes. Diffusions and label spreading are…
Network embedding in heterogeneous information networks (HINs) is a challenging task, due to complications of different node types and rich relationships between nodes. As a result, conventional network embedding techniques cannot work on…
The role of high-degree nodes, or hubs, in shaping graph dynamics and structure is well-recognized in network science, yet their influence remains underexplored in the context of dynamic graph embedding. Recent advances in representation…
Recently, pretraining methods for the Graph Neural Networks (GNNs) have been successful at learning effective representations from unlabeled graph data. However, most of these methods rely on pairwise relations in the graph and do not…
Real-world networks and knowledge graphs are usually heterogeneous networks. Representation learning on heterogeneous networks is not only a popular but a pragmatic research field. The main challenge comes from the heterogeneity -- the…
Self-supervised graph representation learning (SSGRL) is a representation learning paradigm used to reduce or avoid manual labeling. An essential part of SSGRL is graph data augmentation. Existing methods usually rely on heuristics commonly…
RNA-Seq technology offers new high-throughput ways for transcript identification and quantification based on short reads, and has recently attracted great interest. The problem is usually modeled by a weighted splicing graph whose nodes…
Under circumstances of heterophily, where nodes with different labels tend to be connected based on semantic meanings, Graph Neural Networks (GNNs) often exhibit suboptimal performance. Current studies on graph heterophily mainly focus on…
Network embedding aims to represent a network into a low dimensional space where the network structural information and inherent properties are maximumly preserved. Random walk based network embedding methods such as DeepWalk and node2vec…
Graph Neural Networks (GNNs) are computationally demanding and inefficient when applied to graph classification tasks in resource-constrained edge scenarios due to their inherent process, involving multiple rounds of forward and backward…
We propose a novel method, scTree, for single-cell Tree Variational Autoencoders, extending a hierarchical clustering approach to single-cell RNA sequencing data. scTree corrects for batch effects while simultaneously learning a…
With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…
Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…
Real-world graphs are typically complex, exhibiting heterogeneity in the global structure, as well as strong heterophily within local neighborhoods. While a growing body of literature has revealed the limitations of common graph neural…
Unsupervised graph representation learning aims to learn low-dimensional node embeddings without supervision while preserving graph topological structures and node attributive features. Previous graph neural networks (GNN) require a large…