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Related papers: Hypergraph Representations of scRNA-seq Data for I…

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We study the challenges of applying deep learning to gene expression data. We find experimentally that there exists non-linear signal in the data, however is it not discovered automatically given the noise and low numbers of samples used in…

Genomics · Quantitative Biology 2018-06-20 Francis Dutil , Joseph Paul Cohen , Martin Weiss , Georgy Derevyanko , Yoshua Bengio

Many problems such as node classification and link prediction in network data can be solved using graph embeddings. However, it is difficult to use graphs to capture non-binary relations such as communities of nodes. These kinds of complex…

Social and Information Networks · Computer Science 2022-01-27 Sepideh Maleki , Donya Saless , Dennis P. Wall , Keshav Pingali

Sheaf Neural Networks (SNNs) naturally extend Graph Neural Networks (GNNs) by endowing a cellular sheaf over the graph, equipping nodes and edges with vector spaces and defining linear mappings between them. While the attached geometric…

Machine Learning · Computer Science 2024-07-31 Ferran Hernandez Caralt , Guillermo Bernárdez Gil , Iulia Duta , Pietro Liò , Eduard Alarcón Cot

Most network-based protein (or gene) function prediction methods are based on the assumption that the labels of two adjacent proteins in the network are likely to be the same. However, assuming the pairwise relationship between proteins or…

Machine Learning · Statistics 2012-12-04 Loc Tran

We propose a novel method to co-cluster the vertices and hyperedges of hypergraphs with edge-dependent vertex weights (EDVWs). In this hypergraph model, the contribution of every vertex to each of its incident hyperedges is represented…

Data Structures and Algorithms · Computer Science 2021-02-23 Yu Zhu , Boning Li , Santiago Segarra

Hypergraphs, or generalization of graphs such that edges can contain more than two nodes, have become increasingly prominent in understanding complex network analysis. Unlike graphs, hypergraphs have relatively few supporting platforms, and…

Mathematical Software · Computer Science 2024-01-09 Quoc Chuong Nguyen , Trung Kien Le

Molecular interactions often involve high-order relationships that cannot be fully captured by traditional graph-based models limited to pairwise connections. Hypergraphs naturally extend graphs by enabling multi-way interactions, making…

Machine Learning · Computer Science 2025-05-12 Tien Dang , Truong-Son Hy

Networks of genetic expression can be modelled by hypergraphs with the additional structure that real coefficients are given to each vertex-edge incidence. The spectra, i.e. the multiset of the eigenvalues, of such hypergraphs, are known to…

Molecular Networks · Quantitative Biology 2021-09-24 Raffaella Mulas , Michael J. Casey

The task of spatial clustering of transcriptomics data is of paramount importance. It enables the classification of tissue samples into diverse subpopulations of cells, which, in turn, facilitates the analysis of the biological functions of…

Machine Learning · Computer Science 2025-07-29 Mehrad Soltani , Luis Rueda

Hypergraphs provide a natural way to represent higher-order interactions among multiple entities. While undirected hypergraphs have been extensively studied, the case of directed hypergraphs, which can model oriented group interactions,…

Graph representation learning has made major strides over the past decade. However, in many relational domains, the input data are not suited for simple graph representations as the relationships between entities go beyond pairwise…

Machine Learning · Computer Science 2021-01-20 Balasubramaniam Srinivasan , Da Zheng , George Karypis

Graph representation learning based on graph neural networks (GNNs) can greatly improve the performance of downstream tasks, such as node and graph classification. However, the general GNN models do not aggregate node information in a…

Machine Learning · Computer Science 2020-07-30 Fei Ding , Xiaohong Zhang , Justin Sybrandt , Ilya Safro

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja , E. N. Sathishkumar

Identifying cell clusters is a critical step for single-cell transcriptomics study. Despite the numerous clustering tools developed recently, the rapid growth of scRNA-seq volumes prompts for a more (computationally) efficient clustering…

Quantitative Methods · Quantitative Biology 2023-01-11 Nana Wei , Yating Nie , Lin Liu , Xiaoqi Zheng , Hua-Jun Wu4

Graph neural networks (GNNs) with missing node features have recently received increasing interest. Such missing node features seriously hurt the performance of the existing GNNs. Some recent methods have been proposed to reconstruct the…

Machine Learning · Computer Science 2023-02-17 Chengxiang Lei , Sichao Fu , Yuetian Wang , Wenhao Qiu , Yachen Hu , Qinmu Peng , Xinge You

Representing nodes in a network as dense vectors node embeddings is important for understanding a given network and solving many downstream tasks. In particular, for weighted homophilous graphs where similar nodes are connected with larger…

Social and Information Networks · Computer Science 2023-08-14 Jun Hee Kim , Jaeman Son , Hyunsoo Kim , Eunjo Lee

The spectral properties of traditional (dyadic) graphs, where an edge connects exactly two vertices, are widely studied in different applications. These spectral properties are closely connected to the structural properties of dyadic…

Social and Information Networks · Computer Science 2025-06-23 Hao Tian , Shengmin Jin , Reza Zafarani

Inspired by the extensive success of deep learning, graph neural networks (GNNs) have been proposed to learn expressive node representations and demonstrated promising performance in various graph learning tasks. However, existing endeavors…

Machine Learning · Computer Science 2022-04-05 Kaize Ding , Jianling Wang , James Caverlee , Huan Liu

The variety and complexity of relations in multimedia data lead to Heterogeneous Information Networks (HINs). Capturing the semantics from such networks requires approaches capable of utilizing the full richness of the HINs. Existing…

Machine Learning · Computer Science 2023-09-26 Shuai Wang , Jiayi Shen , Athanasios Efthymiou , Stevan Rudinac , Monika Kackovic , Nachoem Wijnberg , Marcel Worring

The ability to model relational information using machine learning has driven advancements across various domains, from medicine to social science. While graph representation learning has become mainstream over the past decade, representing…

Machine Learning · Computer Science 2025-06-12 Iulia Duta , Pietro Liò
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