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Navigation is an essential ability for mobile agents to be completely autonomous and able to perform complex actions. However, the problem of navigation for agents with limited (or no) perception of the world, or devoid of a fully defined…

Robotics · Computer Science 2020-11-30 Danilo Perico , Paulo E. Santos , Reinaldo Bianchi

The purpose of navigation is to determine the position, velocity, and orientation of manned and autonomous platforms, humans, and animals. Obtaining accurate navigation commonly requires fusion between several sensors, such as inertial…

Robotics · Computer Science 2022-11-28 Itzik Klein

This paper presents a mathematical framework for optimizing drug delivery in cancer treatment using a nonlocal model of solid tumor growth. We present a coupled system of partial differential equations that incorporate long-range cellular…

Optimization and Control · Mathematics 2025-03-13 Bouhamidi Abderrahman , El Harraki Imad , Melouani Yassine

As an emerging field of robotics, magnetic-field-controlled soft microrobot has broad application prospects for its flexibility, locomotion diversity as well as remote controllability. Magnetic soft microrobots can perform multimodal…

Materials Science · Physics 2022-02-21 Shangsong Li , Dong Liu , Yuping Hu , Zhijie Su , Xinai Zhang , Ruirui Guo , Dan Li , Yuan Lu

Drug target identification is of significant commercial interest to pharmaceutical companies, and there is a vast amount of research done related to the topic of therapeutic target identification. Interdisciplinary research in this area…

Molecular Networks · Quantitative Biology 2013-07-30 Reka Albert , Bhaskar DasGupta , Nasim Mobasheri

How can a delivery robot navigate reliably to a destination in a new office building, with minimal prior information? To tackle this challenge, this paper introduces a two-level hierarchical approach, which integrates model-free deep…

Artificial Intelligence · Computer Science 2017-10-18 Wei Gao , David Hsu , Wee Sun Lee , Shengmei Shen , Karthikk Subramanian

A numerical model is developed for the motion of superparamagnetic nanoparticles in a non-Newtonian blood flow under the influence of a magnetic field. The rheological properties of blood are modeled by the Carreau flow and viscosity, and…

Biological Physics · Physics 2022-07-14 M. Lee , A. Shelke , S. Singh , J. Fan , P. Zaleski , S. Afkhami

MRI-guided radiation therapy (MRgRT) offers a precise and adaptive approach to treatment planning. Deep learning applications which augment the capabilities of MRgRT are systematically reviewed. MRI-guided radiation therapy offers a…

Medical Physics · Physics 2023-03-31 Zach Eidex , Yifu Ding , Jing Wang , Elham Abouei , Richard L. J. Qiu , Tian Liu , Tonghe Wang , Xiaofeng Yang

We present a navigation system that combines ideas from hierarchical planning and machine learning. The system uses a traditional global planner to compute optimal paths towards a goal, and a deep local trajectory planner and velocity…

We devise an approach for targeted molecular design, a problem of interest in computational drug discovery: given a target protein site, we wish to generate a chemical with both high binding affinity to the target and satisfactory…

Artificial Intelligence · Computer Science 2018-09-07 Tristan Aumentado-Armstrong

Effective robot navigation in unseen environments is a challenging task that requires precise control actions at high frequencies. Recent advances have framed it as an image-goal-conditioned control problem, where the robot generates…

The collective motion of microorganisms and microrobots can be used for particle delivery, especially when guided by external magnetic fields, phototaxis, or chemotaxis. This cargo transport is enhanced significantly by hydrodynamic…

Soft Condensed Matter · Physics 2025-09-30 Maggie Liu , Arnold J. T. M. Mathijssen

Nanorobotics offers an emerging frontier in biomedicine, holding the potential to revolutionize diagnostic and therapeutic applications through its unique capabilities in manipulating biological systems at the nanoscale. Following PRISMA…

Robotics · Computer Science 2024-01-23 Shishir Rajendran , Prathic Sundararajan , Ashi Awasthi , Suraj Rajendran

Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

Human-Computer Interaction · Computer Science 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz

Motivated by problems arising in magnetic drug targeting, we propose to generate an almost constant Kelvin (magnetic) force in a target subdomain, moving along a prescribed trajectory. This is carried out by solving a minimization problem…

Optimization and Control · Mathematics 2017-04-25 Harbir Antil , Ricardo H. Nochetto , Pablo Venegas

The integration of magnetic nanoparticles within fibrillar structures represents an interesting avenue for the remotely controlled release of therapeutic agents. This work presents a novel drug release platform based on electrospun magnetic…

The human-associated microbiome is closely tied to human health and is of substantial clinical interest. Metagenomics-based tools are emerging for clinical diagnostics, tracking the spread of diseases, and surveillance of potential…

The combination of cytotoxic therapies and anti-angiogenic agents is emerging as a most promising strategy in the treatment of malignant tumors. However, the timing and sequencing of these treatments seem to play essential roles in…

Tissues and Organs · Quantitative Biology 2011-06-13 M. Kohandel , C. A. Haselwandter , M. Kardar , S. Sengupta , S. Sivaloganathan

Autonomous robot navigation within the dynamic unknown environment is of crucial significance for mobile robotic applications including robot navigation in last-mile delivery and robot-enabled automated supplies in industrial and hospital…

Robotics · Computer Science 2024-05-14 Kangcheng Liu

The ability to deal with systems parametric uncertainties is an essential issue for heavy self-driving vehicles in unconfined environments. In this sense, robust controllers prove to be efficient for autonomous navigation. However,…

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