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A computational method for magnetically guided drug delivery is presented and the results are compared for the aggregation process of magnetic particles within a fluid environment. The model is developed for the simulation of the…

Soft Condensed Matter · Physics 2015-04-15 N. K. Lampropoulos , E. G. Karvelas , I. E. Sarris

The appearance of a new dangerous and contagious disease requires the development of a drug therapy faster than what is foreseen by usual mechanisms. Many drug therapy developments consist in investigating through different clinical trials…

Quantitative Methods · Quantitative Biology 2020-03-31 Ezequiel Alvarez , Federico Lamagna , Manuel Szewc

Neuronavigation is widely used in biomedical research and interventions to guide the precise placement of instruments around the head to support procedures such as transcranial magnetic stimulation. Traditional systems, however, rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Ziye Xie , Oded Schlesinger , Raj Kundu , Jessica Y. Choi , Pablo Iturralde , Dennis A. Turner , Stefan M. Goetz , Guillermo Sapiro , Angel V. Peterchev , J. Matias Di Martino

This article presents Teledrive, a telepresence robotic system with embodied AI features that empowers an operator to navigate the telerobot in any unknown remote place with minimal human intervention. We conceive Teledrive in the context…

This paper proposes an end-to-end deep reinforcement learning approach for mobile robot navigation with dynamic obstacles avoidance. Using experience collected in a simulation environment, a convolutional neural network (CNN) is trained to…

Robotics · Computer Science 2020-02-12 Guangda Chen , Lifan Pan , Yu'an Chen , Pei Xu , Zhiqiang Wang , Peichen Wu , Jianmin Ji , Xiaoping Chen

We consider a micromanipulation problem in eye surgery, specifically retinal vein cannulation (RVC). RVC involves inserting a microneedle into a retinal vein for the purpose of targeted drug delivery. The procedure requires accurately…

Robotics · Computer Science 2023-07-03 Ji Woong Kim , Peiyao Zhang , Peter Gehlbach , Iulian Iordachita , Marin Kobilarov

We present a target-driven navigation system to improve mapless visual navigation in indoor scenes. Our method takes a multi-view observation of a robot and a target as inputs at each time step to provide a sequence of actions that move the…

Robotics · Computer Science 2022-05-10 Qiaoyun Wu , Xiaoxi Gong , Kai Xu , Dinesh Manocha , Jingxuan Dong , Jun Wang

Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…

Medical Physics · Physics 2018-03-05 Simona Giordanengo , Marco Donetti

Efficient drug delivery is a major challenge in modern medicine and pharmaceutical research. Micrometer-scale robots have recently been proposed as a promising venue to amplify precision of drug administration. Remotely controlled…

Self-driving labs are transforming drug discovery by enabling automated, AI-guided experimentation, but they face challenges in orchestrating complex workflows, integrating diverse instruments and AI models, and managing data efficiently.…

Software Engineering · Computer Science 2025-04-02 Yao Fehlis , Paul Mandel , Charles Crain , Betty Liu , David Fuller

This paper presents a control framework for magnetically actuated cellbots, which combines Model Predictive Control (MPC) with Gaussian Processes (GPs) as a disturbance estimator for precise trajectory tracking. To address the challenges…

Model-based control is a popular paradigm for robot navigation because it can leverage a known dynamics model to efficiently plan robust robot trajectories. However, it is challenging to use model-based methods in settings where the…

Robotics · Computer Science 2019-07-19 Somil Bansal , Varun Tolani , Saurabh Gupta , Jitendra Malik , Claire Tomlin

Magnetically actuated fish-like robots offer promising solutions for underwater exploration due to their miniaturization and agility; however, precise control remains a significant challenge because of nonlinear fluid dynamics, flexible fin…

Robotics · Computer Science 2026-03-06 Akiyuki Koyama , Hiroaki Kawashima

Current developments in molecular electronics, motors and chemical sensors could enable constructing large numbers of devices able to sense, compute and act in micron-scale environments. Such microscopic machines, of sizes comparable to…

Robotics · Computer Science 2023-02-03 Tad Hogg

Despite all the advances achieved in the field of tumor-biology research, in most cases conventional therapies including chemotherapy are still the leading choices. The main disadvantage of these treatments, in addition to the low…

Tissues and Organs · Quantitative Biology 2024-01-25 Paola Sanchez-Moreno , Juan Luis Ortega-Vinuesa , Jose Manuel Peula-Garcia , Juan Antonio Marchal , Houria Boulaiz

This paper suggests an integrated navigation system for an unmanned ground vehicle operating in an unknown cluttered environment. The navigator supports time-critical mobility making it possible for a mobile robot to reach a target from the…

Robotics · Computer Science 2018-08-28 Ahmad A. Masoud , Ali Al-Shaikhi

The control system in surgical robots must ensure patient safety and real time control. As such, all the uncertainties which could appear should be considered into an extended model of the plant. After such an uncertain plant is formed, an…

Robotics · Computer Science 2024-07-24 Vlad Mihaly , Iosif Birlescu , Mircea Şuşcă , Damien Chablat , Petru Dobra

Visual Teach-and-Repeat Navigation is a direct solution for mobile robot to be deployed in unknown environments. However, robust trajectory repeat navigation still remains challenged due to environmental changing and dynamic objects. In…

Robotics · Computer Science 2025-10-13 Jikai Wang , Yunqi Cheng , Kezhi Wang , Zonghai Chen

Robot navigation methods allow mobile robots to operate in applications such as warehouses or hospitals. While the environment in which the robot operates imposes requirements on its navigation behavior, most existing methods do not allow…

Fast feedback control and safety guarantees are essential in modern robotics. We present an approach that achieves both by combining novel robust model predictive control (MPC) with function approximation via (deep) neural networks (NNs).…

Robotics · Computer Science 2020-03-04 Julian Nubert , Johannes Köhler , Vincent Berenz , Frank Allgöwer , Sebastian Trimpe