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Conventionally, 3-dimensional cellular tomography can be done with light sheet or multi-angle observations. Recently, a new technique was introduced where the cell was rotated using convection currents to visualize the outer periphery (Liu…

Metacalibration is a new technique for measuring weak gravitational lensing shear that is unbiased for isolated galaxy images. In this work we test metacalibration with overlapping, or ``blended'' galaxy images. Using standard…

Cosmology and Nongalactic Astrophysics · Physics 2020-10-28 Erin S. Sheldon , Matthew R. Becker , Niall MacCrann , Michael Jarvis

Label-free chemical imaging holds significant promise for improving digital pathology workflows, but data acquisition speed remains a limiting factor. To address this gap, we propose an adaptive strategy-initially scan the low information…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Ji-Hun Oh , Kianoush Falahkheirkhah , Rohit Bhargava

The single sideband (SSB) framework of analytical electron ptychography can account for the presence of residual geometrical aberrations induced by the probe-forming lens. However, the accuracy of this aberration correction method is highly…

Dynamic full-field optical coherence tomography (D-FFOCT) has recently emerged as a label-free imaging tool, capable of resolving cell types and organelles within 3D live samples, whilst monitoring their activity at tens of milliseconds…

Quantitative phase imaging (QPI) is a label-free computational imaging technique used in various fields, including biology and medical research. Modern QPI systems typically rely on digital processing using iterative algorithms for phase…

Optics · Physics 2023-06-28 Yuhang Li , Yi Luo , Deniz Mengu , Bijie Bai , Aydogan Ozcan

We report the modification of a label-free image scanning microscope (ISM) to perform asynchronous 2D imaging at 24kHz while keeping the lateral resolution gain and background rejection of a regular label-free ISM setup. Our method uses a…

Optics · Physics 2023-08-31 Duc-Minh Ta , Alberto Aguilar , Pierre Bon

We propose a realistic scheme for measuring the micromaser linewidth by monitoring the phase diffusion dynamics of the cavity field. Our strategy consists in exciting an initial coherent state with the same photon number distribution as the…

Quantum Physics · Physics 2009-11-07 F. Casagrande , A. Ferraro , A. Lulli , R. Bonifacio , E. Solano , H. Walther

Holography is an essential technique of generating three-dimensional images. Recently, quantum holography with undetected photons (QHUP) has emerged as a groundbreaking method capable of capturing complex amplitude images. Despite its…

A new numerically and experimentally tested measurement method for the local electrical light field including its phase is presented. The method is based on Self Referencing Interferograms (SRI) such as shearing interferograms. The complex…

Instrumentation and Detectors · Physics 2016-10-27 Martin Berz , Cordelia Berz

Holography is an established technique for measuring the wavefront of optical signals through interferometric combination with a reference wave. Conventionally the integration time of a hologram is limited by the interferometer coherence…

Optics · Physics 2023-12-13 Guillaume Thekkadath , Duncan England , Benjamin Sussman

We introduce HAMscope, a compact, snapshot hyperspectral autofluorescence miniscope that enables real-time, label-free molecular imaging in a wide range of biological systems. By integrating a thin polymer diffuser into a widefield…

We demonstrate accurate phase measurement from low photon level interference data using a constrained optimization method that takes into account the expected redundancy in the unknown phase function. This approach is shown to have…

Quantum Physics · Physics 2015-06-23 Mandeep Singh , Kedar Khare , Anand Kumar Jha , Shashi Prabhakar , R. P. Singh

We present an algorithm for coherent diffractive imaging with phaseless measurements. It treats the forward model as a combination of coherent and incoherent waves. The algorithm reconstructs absorption and phase contrast that quantifies…

Computational Physics · Physics 2022-08-25 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

Capturing biological specimens at large scales with sub-micron resolution is crucial for biomedical research, but conventional cameras often can't handle the pixel requirements. While most microscopes use motorized stages to move samples…

Optics · Physics 2025-03-28 Charlie Kersuzan , Aymerick Bazin , Amaury Badon

We present a powerful and cost-effective method for active illumination using a digital micromirror device (DMD) for quantitative phase imaging techniques. Displaying binary illumination patterns on a DMD with appropriate spatial filtering,…

Optics · Physics 2023-07-19 Seungwoo Shin , Kyoohyun Kim , Jonghee Yoon , YongKeun Park

We systematically evaluate a Deep Learning (DL) method in a 3D medical image segmentation task. Our segmentation method is integrated into the radiosurgery treatment process and directly impacts the clinical workflow. With our method, we…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Boris Shirokikh , Alexandra Dalechina , Alexey Shevtsov , Egor Krivov , Valery Kostjuchenko , Amayak Durgaryan , Mikhail Galkin , Andrey Golanov , Mikhail Belyaev

Scientific imaging often involves long acquisition times to obtain high-quality data, especially when probing complex, heterogeneous systems. However, reducing acquisition time to increase throughput inevitably introduces significant noise…

Artificial Intelligence · Computer Science 2025-05-14 Petrus H. Zwart , Tamas Varga , Odeta Qafoku , James A. Sethian

We report on amplitude and phase imaging of out-of-plane sinusoidal surface vibration at nanometer scales with a heterodyne holographic interferometer. The originality of the proposed method is to make use of a multiplexed local oscillator…

We present a method, referred to as Deep Harmonic Finesse (DHF), for separation of non-stationary quasi-periodic signals when limited data is available. The problem frequently arises in wearable systems in which, a combination of…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Mahya Saffarpour , Kourosh Vali , Weitai Qian , Begum Kasap , Herman L. Hedriana , Soheil Ghiasi