Related papers: Elucidating the high compliance mechanism by which…
This study employs micro-computed tomography (micro-CT) to unravel the geometrical intricacies of the rat urinary bladder wall during various states of ex-vivo filling, contrasting markedly with the commonly held idealizations of uniform…
Bladder function is typically assessed through pressure volume relations, compliance indices and flow measurements, whereas structural evaluation relies largely on qualitative imaging findings. These approaches do not formally quantify how…
The study of elastic structures embedded with fluid-filled cavities received considerable attention in fields such as autonomous materials, sensors, actuators, and smart systems. This work studies an elastic beam embedded with a set of…
Two dimensional active fluids display a transition from turbulent to coherent flow upon decreasing the size of the confining geometry. A recent experiment suggests that the behavior in three dimensions is remarkably different; emergent…
In this work, we present a mathematical model of the initiation and progression of a low-grade urinary bladder carcinoma. We simulate the crucial processes involved in tumor growth, such as oxygen diffusion, carcinogen penetration, and…
In this work, we reevaluated long standing conjectures as to the source of the exceptionally large compliance of the bladder wall. Whereas, these conjectures were based on indirect measures of loading mechanisms, in this work we take…
Background and Objective: Pelvic floor disorders are prevalent diseases and patient care remains difficult as the dynamics of the pelvic floor remains poorly known. So far, only 2D dynamic observations of straining exercises at excretion…
Purpose. - Radiotherapy is an important treatment for prostate cancer.During treatment sessions, bladder and rectal repletion is difficult to quantify and cannot be measured with a single and initial CT scan acquisition. Some methods, such…
Volumetry is one of the principal downstream applications of 3D medical image segmentation, for example, to detect abnormal tissue growth or for surgery planning. Conformal Prediction is a promising framework for uncertainty quantification,…
A sensation of fullness in the bladder is a regular experience, yet the mechanisms that act to generate this sensation remain poorly understood. This is an important issue because of the clinical problems that can result when this system…
Extensive coarse grained molecular dynamics simulations are performed to investigate the conformational phase diagram of a neutral polymer in the presence of attractive crowders. We show that, for low crowded densities, the polymer…
Three-dimensional ultrasound enables real-time volumetric visualization of anatomical structures. Unlike traditional 2D ultrasound, 3D imaging reduces reliance on precise probe orientation, potentially making ultrasound more accessible to…
Balloon dilation catheters are often used to quantify the physiological state of peristaltic activity in tubular organs and comment on their ability to propel fluid which is important for healthy human function. To fully understand this…
Many urological studies rely upon animal models such as rats and pigs whose urination physics and correlation to humans are poorly understood. Here we elucidate the hydrodynamics of urination across five orders of magnitude in animal mass.…
This work analyzes the viscous flow and elastic deformation created by the forced axial motion of a rigid cylinder within an elastic liquid-filled tube. The examined configuration is relevant to various minimally invasive medical procedures…
The dynamics of entrainment of finite-size heavy particles in a turbulent open channel flow over a smooth surface are analyzed. Three types of simulations, namely with freely moving, rotation-constrained, and spanwise-motion-constrained…
The dynamics of compaction of hard cross-shaped pentamers on the 2D square lattice is investigated. The addition of new particles is controlled by diffusive relaxation. It is shown that the filling process terminates at a glassy phase with…
The performances of lubricated systems widely used in natural, biological, and artificial settings are traditionally dictated by their load bearing capacities. Here we unveil that, by exploiting a unique coupling between interfacial…
Despite being of vital importance to the immune system, the mechanism by which cells engulf relatively large solid particles during phagocytosis is still poorly understood. From movies of neutrophil phagocytosis of polystyrene beads, we…
The present study focuses on the assessment of the performance of a Finite Volume Method based, particle-resolved simulation approach to predict the flow through a model packed-bed consisting of 21 layers of spheres arranged in the body…