Modelling afferent nerve responses to bladder filling
Tissues and Organs
2015-10-13 v1
Abstract
A sensation of fullness in the bladder is a regular experience, yet the mechanisms that act to generate this sensation remain poorly understood. This is an important issue because of the clinical problems that can result when this system does not function properly. The aim of the study group activity was to develop mathematical models that describe the mechanics of bladder filling, and how stretch modulates the firing rate of afferent nerves. Several models were developed, which were qualitatively consistent with experimental data obtained from a mouse model.
Cite
@article{arxiv.1510.03119,
title = {Modelling afferent nerve responses to bladder filling},
author = {Maryam Argungu and Saziye Bayram and Bindi Brook and Buddhapriya Chakrabarti and Richard H Clayton and Donna M Daly and Rosemary J Dyson and Craig Holloway and Varun Manhas and Shailesh Naire and Tom Shearer and Radostin D. Simitev},
journal= {arXiv preprint arXiv:1510.03119},
year = {2015}
}
Comments
This report summarises the outcomes from a problem posed at the UK MMSG NC3R's \& POEMS Study Group meeting, 8--12 Sept 2014, Cambridge