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Interactive visualization of large scholarly knowledge graphs combined with LLM reasoning shows promise butremains under-explored. We address this gap by developing an interactive visualization system for the Cell Map forAI Talent Knowledge…

Digital Libraries · Computer Science 2025-08-28 Jiawei Xu , Juichien Chen , Yilin Ye , Zhandos Sembay , Swathi Thaker , Pamela Payne-Foster , Jake Chen , Ying Ding

Knowledge graphs and ontologies represent entities and their relationships in a structured way, having gained significance in the development of modern AI applications. Integrating these semantic resources with machine learning models often…

Machine Learning · Computer Science 2025-09-10 Hamid Ahmad , Heiko Paulheim , Rita T. Sousa

Knowledge Graphs (KG) constitute a flexible representation of complex relationships between entities particularly useful for biomedical data. These KG, however, are very sparse with many missing edges (facts) and the visualisation of the…

Artificial Intelligence · Computer Science 2016-12-08 Armando Vieira

Biomedical knowledge is fragmented across siloed databases -- Reactome for pathways, STRING for protein interactions, ClinicalTrials.gov for study registries, DrugBank for drug vocabularies, DGIdb for drug-gene interactions, SIDER for side…

Databases · Computer Science 2026-03-19 Madhulatha Mandarapu , Sandeep Kunkunuru

Knowledge graphs (KGs) have emerged as a powerful framework for representing and integrating complex biomedical information. However, assembling KGs from diverse sources remains a significant challenge in several aspects, including entity…

Machine Learning · Computer Science 2023-10-10 Yijia Xiao , Dylan Steinecke , Alexander Russell Pelletier , Yushi Bai , Peipei Ping , Wei Wang

The availability of vast amounts of visual data with heterogeneous features is a key factor for developing, testing, and benchmarking of new computer vision (CV) algorithms and architectures. Most visual datasets are created and curated for…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Jicheng Yuan , Anh Le-Tuan , Manh Nguyen-Duc , Trung-Kien Tran , Manfred Hauswirth , Danh Le-Phuoc

We explore the potential for combining generative AI with grammar-based visualizations for biomedical data discovery. In our prototype, we use a multi-agent system to generate visualization specifications and apply filters. These…

Human-Computer Interaction · Computer Science 2025-09-23 Devin Lange , Shanghua Gao , Pengwei Sui , Austen Money , Priya Misner , Marinka Zitnik , Nils Gehlenborg

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

Human-Computer Interaction · Computer Science 2021-10-22 Fahd Husain , Rosa Romero-Gomez , Emily Kuang , Dario Segura , Adamo Carolli , Lai Chung Liu , Manfred Cheung , Yohann Paris

Biomedical knowledge graphs (KG) are heterogenous networks consisting of biological entities as nodes and relations between them as edges. These entities and relations are extracted from millions of research papers and unified in a single…

Artificial Intelligence · Computer Science 2022-11-11 Dattaraj J. Rao , Shraddha S. Mane , Mukta A. Paliwal

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

Computation and Language · Computer Science 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Pursuing artificial intelligence for biomedical science, a.k.a. AI Scientist, draws increasing attention, where one common approach is to build a copilot agent driven by Large Language Models (LLMs). However, to evaluate such systems,…

Computation and Language · Computer Science 2024-07-02 Xinna Lin , Siqi Ma , Junjie Shan , Xiaojing Zhang , Shell Xu Hu , Tiannan Guo , Stan Z. Li , Kaicheng Yu

Representation learning provides new and powerful graph analytical approaches and tools for the highly valued data science challenge of mining knowledge graphs. Since previous graph analytical methods have mostly focused on homogeneous…

Information Retrieval · Computer Science 2019-05-29 Zheng Gao , Gang Fu , Chunping Ouyang , Satoshi Tsutsui , Xiaozhong Liu , Jeremy Yang , Christopher Gessner , Brian Foote , David Wild , Qi Yu , Ying Ding

Large Language Models~(LLMs) have demonstrated capabilities across various applications but face challenges such as hallucination, limited reasoning abilities, and factual inconsistencies, especially when tackling complex, domain-specific…

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Artificial Intelligence · Computer Science 2023-07-18 Lauren Nicole DeLong , Ramon Fernández Mir , Zonglin Ji , Fiona Niamh Coulter Smith , Jacques D. Fleuriot

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Modern distributed decision-making systems face significant challenges arising from data heterogeneity, dynamic environments, and the need for decentralized coordination. This paper introduces the Knowledge Sharing paradigm as an innovative…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-10 Rosario Napoli , Gabriele Morabito , Antonio Celesti , Massimo Villari , Maria Fazio

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

Machine Learning · Computer Science 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Advancements in Artificial Intelligence (AI) and deep neural networks have driven significant progress in vision and text processing. However, achieving human-like reasoning and interpretability in AI systems remains a substantial…

Artificial Intelligence · Computer Science 2025-02-19 Shenzhe Zhu , Shengxiang Sun

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Knowledge graphs (KGs) are an important tool for representing complex relationships between entities in the biomedical domain. Several methods have been proposed for learning embeddings that can be used to predict new links in such graphs.…

Artificial Intelligence · Computer Science 2026-05-12 Daniel Daza , Dimitrios Alivanistos , Payal Mitra , Thom Pijnenburg , Michael Cochez , Paul Groth
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