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A key resource for quantum optics experiments is an on-demand source of single and multiple photon states at telecommunication wavelengths. This letter presents a heralded single photon source based on a hybrid technology approach,…

Real time, singleshot multispectral imaging systems are crucial for environment monitoring and biomedical imaging. Most singleshot multispectral imagers rely on complex computational backends, which precludes real time operations. In this…

Optics · Physics 2025-02-27 Romil Audhkhasi , Ningzhi Xie , Johannes E. Fröch , Arka Majumdar

Measuring subdiffraction separations between single fluorescent particles is important for biological, nano-, and medical-technology studies. Major challenges include (i) measuring changing molecular separations with high temporal…

Biological Physics · Physics 2015-05-18 Shawn H. DeCenzo , Michael C. DeSantis , Y. M. Wang

We introduce a novel laser-scanning optical microscopy technique that employs optical-frequency-comb (OFC) lasers. This method facilitates multimodal spectroscopic imaging by analyzing interferograms produced via a dual-comb spectroscopic…

Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar

Optical sectioning technology has been widely used in various fluorescence microscopes owing to its background removing capability. Here, a virtual HiLo based on edge detection (V-HiLo-ED) is proposed to achieve wide-field optical…

Optics · Physics 2021-11-08 Yuyao Hu , Dong Liang , Jing Wang , Yaping Xuan , Fu Zhao , Jun Liu , Ruxin Li

Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…

We introduce a wide field hyperspectral microscope using the Fourier-transform approach. The interferometer is based on the Translating-Wedge-Based Identical Pulses eNcoding System (TWINS) [Opt. Lett. 37, 3027 (2012)], a common-path…

Instrumentation and Detectors · Physics 2019-09-26 A. Candeo , B. E. Nogueira de Faria , M. Erreni , G. Valentini , A. Bassi , A. M. de Paula , G. Cerullo , C. Manzoni

We report on the recently emerging (Laser) Light Sheet based Fluorescence Microscopy field (LSFM). The techniques used in this field allow to study and visualize biomedical objects non-destructively in high-resolution through virtual…

Instrumentation and Detectors · Physics 2011-06-17 Jan A. N. Buytaert , Emilie Descamps , Dominique Adriaens , Joris J. J. Dirckx

Confocal microscopy is the cornerstone of cellular biology and biomedical research due to its non-destructive imaging, compatibility with live cells, sensitivity, optical sectioning, and subcellular resolution. To meet the demand for rapid…

High-dimensional biphoton states are promising resources for quantum applications, ranging from high-dimensional quantum communications to quantum imaging. A pivotal task is fully characterising these states, which is generally…

Quantum Physics · Physics 2023-02-20 Danilo Zia , Nazanin Dehghan , Alessio D'Errico , Fabio Sciarrino , Ebrahim Karimi

A method for direct phase difference reconstruction using single-shot dual-wavelength off-axis digital holography is presented. This approach enables direct imaging of samples with high steps without the need to reconstruct phase images at…

Optics · Physics 2025-07-30 M. Amani , M. Dashtdar

Advanced microscopy techniques are essential in biomedical research for visualising and tracking biomolecules within living cells and their compartments. Conventional fluorescence microscopy methods, however, often struggle with accurately…

Fourier ptychographic microscopy allows for the collection of images with a high space-bandwidth product at the cost of temporal resolution. In Fourier ptychographic microscopy, the light source of a conventional widefield microscope is…

Image and Video Processing · Electrical Eng. & Systems 2019-01-30 Yi Fei Cheng , Megan Strachan , Zachary Weiss , Moniher Deb , Dawn Carone , Vidya Ganapati

In order to discern aggregation in solutions, we present a quantum mechanical analog of the photon statistics from fluorescent molecules diffusing through a focused beam. A generating functional is developed to fully describe the…

Biological Physics · Physics 2009-11-10 Hai-cang Ren , Noel L. Goddard , Gregoire Altan-Bonnet , Albert Libchaber

This paper presents a smartphone-based imaging system capable of quantifying the concentration of an assortment of biological/chemical assay samples. The main objective is to construct an image database which characterizes the relationship…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Zhendong Cao , Hongji Dai , Zhida Li , Ash Parameswaran

Two-dimensional electronic spectroscopy provides information on coupling and energy transfer between excited states on ultrafast timescales. Only recently, incoherent fluorescence detection has made it possible to combine this method with…

Optics · Physics 2025-05-14 Sanchayeeta Jana , Simon Durst , Lucas Ludwig , Markus Lippitz

In stellar interferometry, image quality improves significantly with the inclusion of more telescopes and the use of phase closure. We demonstrate, using first coherent and then partially coherent white light, a compact and efficient…

Astrophysics · Physics 2009-11-13 E. N. Ribak , M. Gai , D. Loreggia , S. G. Lipson

Multifocus microscopy enables recording of entire volumes in a single camera exposure. In dense samples, multifocus microscopy is severely hampered by background haze. Here, we introduce a scalable multifocus method that incorporates…

The spatial structure of single photons is becoming an extensively explored resource used for facilitating the free-space quantum key distribution and quantum computation as well as for benchmarking the limits of quantum entanglement…

Quantum Physics · Physics 2016-11-08 Radosław Chrapkiewicz , Michał Jachura , Konrad Banaszek , Wojciech Wasilewski