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Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Populations of heterogeneous cells play an important role in many biological systems. In this paper we consider systems where each cell can be modelled by an ordinary differential equation. To account for heterogeneity, parameter values are…

Quantitative Methods · Quantitative Biology 2009-09-27 Steffen Waldherr , Jan Hasenauer , Frank Allgöwer

In many biological processes heterogeneity within cell populations is an important issue. In this work we consider populations where the behavior of every single cell can be described by a system of ordinary differential equations.…

Molecular Networks · Quantitative Biology 2010-02-25 J. Hasenauer , S. Waldherr , M. Doszczak , P. Scheurich , F. Allgower

Pollen grains are known for their impressive variety of species-specific, microscale surface patterning. Despite having similar biological developmental steps, pollen grain surface features are remarkably geometrically varied. Previous work…

Soft Condensed Matter · Physics 2019-02-15 Asja Radja , Eric M. Horsley , Maxim O. Lavrentovich , Alison M. Sweeney

A two-dimensional lattice model for the formation and evolution of shear bands in granular media is proposed. Each lattice site is assigned a random variable which reflects the local density. At every time step, the strain is localized…

Statistical Mechanics · Physics 2013-05-29 Janos Torok , Supriya Krishnamurthy , Janos Kertesz , Stephane Roux

Flocks of birds and schools of fish are familiar examples of spatial patterns formed by living organisms. In contrast to the patterns on the skins of, say, zebra and giraffe, the patterns of our interest are {\it transient} although…

Populations and Evolution · Quantitative Biology 2007-05-23 Debashish Chowdhury , Katsuhiro Nishinari , Andreas Schadschneider

We motivate and analyze a simple model for the formation of banded vegetation patterns. The model incorporates a minimal number of ingredients for vegetation growth in semi-arid landscapes. It allows for comprehensive analysis and sheds new…

Pattern Formation and Solitons · Physics 2022-07-04 Arnd Scheel , Jasper Weinburd

Spatial organization of proteins in cells is important for many biological functions. In general, the nonlinear, spatially coupled models for protein-pattern formation are only accessible to numerical simulations, which has limited insight…

Pattern Formation and Solitons · Physics 2021-04-16 Fridtjof Brauns , Jacob Halatek , Erwin Frey

Spatial organisation is a hallmark of all living cells, and recreating it in model systems is a necessary step in the creation of synthetic cells. It is therefore of both fundamental and practical interest to better understand the basic…

Biological Physics · Physics 2017-12-19 Jaime Agudo-Canalejo , Ramin Golestanian

The self-organization of proteins into enriched compartments and the formation of complex patterns are crucial processes for life on the cellular level. Liquid-liquid phase separation is one mechanism for forming such enriched compartments.…

Soft Condensed Matter · Physics 2025-04-07 Antonia Winter , Yuhao Liu , Alexander Ziepke , George Dadunashvili , Erwin Frey

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

Adaptation and Self-Organizing Systems · Physics 2022-02-01 Ria Ghosh , Shakti N. Menon

Bacterial cells navigate around their environment by directing their movement along chemical gradients. This process, known as chemotaxis, can promote the rapid expansion of bacterial populations into previously unoccupied territories.…

Populations and Evolution · Quantitative Biology 2022-06-08 Avaneesh V. Narla , Jonas Cremer , Terry Hwa

Anisotropic collective patterns occur frequently in the morphogenesis of 2D biofilms. These patterns are often attributed to growth regulation mechanisms and differentiation based on gradients of diffusing nutrients and signalling…

Biological Physics · Physics 2017-10-11 Cameron Zachreson , Xinhui Yap , Erin S. Gloag , Raz Shimoni , Cynthia B. Whitchurch , Milos Toth

Bacteria live in environments that are continuously fluctuating and changing. Exploiting any predictability of such fluctuations can lead to an increased fitness. On longer timescales bacteria can "learn" the structure of these fluctuations…

Cell Behavior · Quantitative Biology 2021-01-05 Stefan Landmann , Caroline M. Holmes , Mikhail Tikhonov

How motile bacteria move near a surface is a problem of fundamental biophysical interest and is key to the emergence of several phenomena of biological, ecological and medical relevance, including biofilm formation. Solid boundaries can…

Biological Physics · Physics 2019-09-12 Stanislaw Makarchuk , Vasco C. Braz , Nuno A. M. Araújo , Lena Ciric , Giorgio Volpe

We use moving light patterns to control the motion of {\it Escherichia coli} bacteria whose motility is photo-activated. Varying the pattern speed controls the magnitude and direction of the bacterial flux, and therefore the accumulation of…

In this work, we present a computational analysis of the planar wave propagation behavior of a one-dimensional periodic multi-stable cellular material. Wave propagation in these materials is interesting because they combine the ability of…

Applied Physics · Physics 2019-11-19 Camilo Valencia , David Restrepo , Nilesh D. mankame , Pablo D. Zavattieri , Juan Gomez

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological…

Statistical Mechanics · Physics 2009-11-10 A. Gamba , D. Ambrosi , A. Coniglio , A. de Candia , S. Di Talia , E. Giraudo , G. Serini , L. Preziosi , F. Bussolino

Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions via changes in cell morphologies and macromolecular composition. How bacterial morphologies are regulated in diverse environmental conditions is a…

Cell Behavior · Quantitative Biology 2021-10-26 Diana Serbanescu , Nikola Ojkic , Shiladitya Banerjee
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