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Physics-Informed Neural Networks (PINNs) have been shown to be an effective way of incorporating physics-based domain knowledge into neural network models for many important real-world systems. They have been particularly effective as a…

Machine Learning · Computer Science 2022-11-23 Jian Cheng Wong , Pao-Hsiung Chiu , Chin Chun Ooi , My Ha Da

Physics-informed neural networks (PINNs) have recently emerged as effective methods for solving partial differential equations (PDEs) in various problems. Substantial research focuses on the failure modes of PINNs due to their frequent…

Machine Learning · Computer Science 2024-10-01 Yesom Park , Changhoon Song , Myungjoo Kang

In this study, we present and validate the predictive capability of the Physics-Informed Neural Networks (PINNs) methodology for solving a variety of engineering and biological dynamical systems governed by ordinary differential equations…

Machine Learning · Computer Science 2025-11-19 Tyrus Whitman , Andrew Particka , Christopher Diers , Ian Griffin , Charuka Wickramasinghe , Pradeep Ranaweera

Recently, a class of machine learning methods called physics-informed neural networks (PINNs) has been proposed and gained prevalence in solving various scientific computing problems. This approach enables the solution of partial…

Computational Engineering, Finance, and Science · Computer Science 2023-11-06 Chen Xu , Ba Trung Cao , Yong Yuan , Günther Meschke

Physics-informed machine learning (PIML) has emerged as a promising new approach for simulating complex physical and biological systems that are governed by complex multiscale processes for which some data are also available. In some…

Machine Learning · Computer Science 2022-05-18 Khemraj Shukla , Mengjia Xu , Nathaniel Trask , George Em Karniadakis

We present a new physics informed neural network (PINN) algorithm for solving brittle fracture problems. While most of the PINN algorithms available in the literature minimize the residual of the governing partial differential equation, the…

Machine Learning · Statistics 2019-07-08 Somdatta Goswami , Cosmin Anitescu , Souvik Chakraborty , Timon Rabczuk

Inverse problems arise across scientific and engineering domains, where the goal is to infer hidden parameters or physical fields from indirect and noisy observations. Classical approaches, such as variational regularization and Bayesian…

Machine Learning · Statistics 2025-12-03 Ali Mohammad-Djafari , Ning Chu , Li Wang

Scientific Machine Learning (SciML) integrates physics and data into the learning process, offering improved generalization compared with purely data-driven models. Despite its potential, applications of SciML in prognostics remain limited,…

Machine Learning · Computer Science 2025-11-04 Ibai Ramirez , Jokin Alcibar , Joel Pino , Mikel Sanz , David Pardo , Jose I. Aizpurua

Physics-informed neural networks (PINNs) have emerged as a powerful tool for solving inverse problems, especially in cases where no complete information about the system is known and scatter measurements are available. This is especially…

Computational Engineering, Finance, and Science · Computer Science 2023-08-03 Jeremias Garay , Jocelyn Dunstan , Sergio Uribe , Francisco Sahli Costabal

We propose Gradient Informed Neural Networks (GradINNs), a methodology inspired by Physics Informed Neural Networks (PINNs) that can be used to efficiently approximate a wide range of physical systems for which the underlying governing…

Machine Learning · Computer Science 2024-09-04 Filippo Aglietti , Francesco Della Santa , Andrea Piano , Virginia Aglietti

Physics-Informed Neural Networks (PINNs) have emerged as a highly active research topic across multiple disciplines in science and engineering, including computational geomechanics. PINNs offer a promising approach in different applications…

Computational Engineering, Finance, and Science · Computer Science 2024-04-30 Yared W. Bekele

Physics-Informed Neural Networks (PINNs) show significant potential for solving inverse problems, especially when observations are limited and sparse, provided that the relevant physical equations are known. We use PINNs to estimate smooth…

Numerical Analysis · Mathematics 2025-08-06 Moises Sierpe , Ernesto Castillo , Hernan Mella , Felipe Galarce

The utilization of Deep Neural Networks (DNNs) in physical science and engineering applications has gained traction due to their capacity to learn intricate functions. While large datasets are crucial for training DNN models in fields like…

Machine Learning · Computer Science 2025-08-05 Vamsi Sai Krishna Malineni , Suresh Rajendran

The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…

Populations and Evolution · Quantitative Biology 2024-01-15 Marianna Karapitta , Andreas Kasis , Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Physics-informed neural networks (PINNs) have been proposed to solve two main classes of problems: data-driven solutions and data-driven discovery of partial differential equations. This task becomes prohibitive when such data is highly…

Machine Learning · Computer Science 2022-10-20 Wei Peng , Wen Yao , Weien Zhou , Xiaoya Zhang , Weijie Yao

The outbreaks of Coronavirus Disease 2019 (COVID-19) have impacted the world significantly. Modeling the trend of infection and real-time forecasting of cases can help decision making and control of the disease spread. However, data-driven…

Populations and Evolution · Quantitative Biology 2020-09-18 Zhijian Li , Yunling Zheng , Jack Xin , Guofa Zhou

Deep learning has been shown to be an effective tool in solving partial differential equations (PDEs) through physics-informed neural networks (PINNs). PINNs embed the PDE residual into the loss function of the neural network, and have been…

Machine Learning · Computer Science 2022-04-06 Jeremy Yu , Lu Lu , Xuhui Meng , George Em Karniadakis

Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs…

Quantitative Methods · Quantitative Biology 2021-01-27 John H. Lagergren , John T. Nardini , Ruth E. Baker , Matthew J. Simpson , Kevin B. Flores

In complex engineering systems such as electro-thermal-fluid coupling, rapid and accurate prediction of multi-physics fields is essential for advanced applications like digital twins and real-time condition monitoring. Traditional numerical…

Computational Physics · Physics 2026-03-25 Baitong Zhou , Ze Tao , Fujun Liu , Xuan Fang