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Related papers: Automated Retrosynthesis Planning of Macromolecule…

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Chemical reasoning usually involves complex, multi-step processes that demand precise calculations, where even minor errors can lead to cascading failures. Furthermore, large language models (LLMs) encounter difficulties handling…

Computation and Language · Computer Science 2025-01-14 Xiangru Tang , Tianyu Hu , Muyang Ye , Yanjun Shao , Xunjian Yin , Siru Ouyang , Wangchunshu Zhou , Pan Lu , Zhuosheng Zhang , Yilun Zhao , Arman Cohan , Mark Gerstein

This paper introduces AnalyticsGPT, an intuitive and efficient large language model (LLM)-powered workflow for scientometric question answering. This underrepresented downstream task addresses the subcategory of meta-scientific questions…

Computation and Language · Computer Science 2026-02-11 Khang Ly , Georgios Cheirmpos , Adrian Raudaschl , Christopher James , Seyed Amin Tabatabaei

Motivation: Retrosynthesis planning poses a formidable challenge in the organic chemical industry. Single-step retrosynthesis prediction, a crucial step in the planning process, has witnessed a surge in interest in recent years due to…

Chemical Physics · Physics 2024-04-22 Kaipeng Zeng , Bo yang , Xin Zhao , Yu Zhang , Fan Nie , Xiaokang Yang , Yaohui Jin , Yanyan Xu

Automated data preparation is crucial for democratizing machine learning, yet existing reinforcement learning (RL) based approaches suffer from inefficient exploration in the vast space of possible preprocessing pipelines. We present…

Databases · Computer Science 2025-07-21 Jing Chang , Chang Liu , Jinbin Huang , Rui Mao , Jianbin Qin

Growing concerns about climate change and sustainability are driving manufacturers to take significant steps toward reducing their carbon footprints. For these manufacturers, a first step towards this goal is to identify the environmental…

Computation and Language · Computer Science 2025-02-12 Steffen Castle , Julian Moreno Schneider , Leonhard Hennig , Georg Rehm

Enlarging the context window of large language models (LLMs) has become a crucial research area, particularly for applications involving extremely long texts. In this work, we propose a novel training-free framework for processing long…

Computation and Language · Computer Science 2024-10-15 Zihan Zhou , Chong Li , Xinyi Chen , Shuo Wang , Yu Chao , Zhili Li , Haoyu Wang , Rongqiao An , Qi Shi , Zhixing Tan , Xu Han , Xiaodong Shi , Zhiyuan Liu , Maosong Sun

The versatility of large language models (LLMs) has been explored across various sectors, but their application in healthcare poses challenges, particularly in the domain of pharmaceutical contraindications where accurate and reliable…

Artificial Intelligence · Computer Science 2025-08-11 Byeonghun Bang , Jongsuk Yoon , Dong-Jin Chang , Seho Park , Yong Oh Lee

This study investigates large language model (LLM) -based multi-agent systems (MASs) as a promising approach to inventory management, which is a key component of supply chain management. Although these systems have gained considerable…

Multiagent Systems · Computer Science 2026-02-06 Konosuke Yoshizato , Kazuma Shimizu , Ryota Higa , Takanobu Otsuka

Automated machine learning (AutoML) accelerates AI development by automating tasks in the development pipeline, such as optimal model search and hyperparameter tuning. Existing AutoML systems often require technical expertise to set up…

Machine Learning · Computer Science 2025-06-09 Patara Trirat , Wonyong Jeong , Sung Ju Hwang

Understanding large-scale, complex software systems is a major challenge for developers, who spend a significant portion of their time on program comprehension. Traditional tools such as static visualizations and reverse engineering…

Software Engineering · Computer Science 2025-08-11 Yoseph Berhanu Alebachew

Large Language Models (LLMs) have shown remarkable capabilities in natural language tasks requiring complex reasoning, yet their application in agentic, multi-step reasoning within interactive environments remains a difficult challenge.…

Artificial Intelligence · Computer Science 2024-08-15 Pranav Putta , Edmund Mills , Naman Garg , Sumeet Motwani , Chelsea Finn , Divyansh Garg , Rafael Rafailov

We have developed an end-to-end, retrosynthesis system, named ChemiRise, that can propose complete retrosynthesis routes for organic compounds rapidly and reliably. The system was trained on a processed patent database of over 3 million…

Chemical Physics · Physics 2021-08-11 Xiangyan Sun , Ke Liu , Yuquan Lin , Lingjie Wu , Haoming Xing , Minghong Gao , Ji Liu , Suocheng Tan , Zekun Ni , Qi Han , Junqiu Wu , Jie Fan

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Retrosynthesis, which aims to find a route to synthesize a target molecule from commercially available starting materials, is a critical task in drug discovery and materials design. Recently, the combination of ML-based single-step reaction…

Artificial Intelligence · Computer Science 2024-03-05 Guoqing Liu , Di Xue , Shufang Xie , Yingce Xia , Austin Tripp , Krzysztof Maziarz , Marwin Segler , Tao Qin , Zongzhang Zhang , Tie-Yan Liu

Systematic reviews require the use of rigorously designed search strategies to ensure both comprehensive retrieval and minimization of bias. Conventional manual approaches, although methodologically systematic, are resource-intensive and…

Information Retrieval · Computer Science 2026-02-03 Fatima Nasser , Fouad Trad , Ammar Mohanna , Ghada El-Hajj Fuleihan , Ali Chehab

We introduce a multicrossmodal LLM-agent framework motivated by the growing volume and diversity of materials-science data ranging from high-resolution microscopy and dynamic simulation videos to tabular experiment logs and sprawling…

Materials Science · Physics 2025-05-22 Adib Bazgir , Rama chandra Praneeth Madugula , Yuwen Zhang

Manufacturing planners face complex operational challenges that require seamless collaboration between human expertise and intelligent systems to achieve optimal performance in modern production environments. Traditional approaches to…

Artificial Intelligence · Computer Science 2025-12-23 Himabindu Thogaru , Saisubramaniam Gopalakrishnan , Zishan Ahmad , Anirudh Deodhar

Large language models (LLMs) are widely used in retrieval-augmented generation (RAG) to incorporate external knowledge at inference time. However, when retrieved contexts are noisy, incomplete, or heterogeneous, a single generation process…

Computation and Language · Computer Science 2026-04-22 Xingchen Xiao , Heyan Huang , Runheng Liu , Jincheng Xie

Schema matching is a crucial task in data integration, involving the alignment of a source schema with a target schema to establish correspondence between their elements. This task is challenging due to textual and semantic heterogeneity,…

Databases · Computer Science 2024-05-31 Eitam Sheetrit , Menachem Brief , Moshik Mishaeli , Oren Elisha

The study of biological materials and bio-inspired materials science is well established; however, surprisingly little knowledge has been systematically translated to engineering solutions. To accelerate discovery and guide insights, an…

Materials Science · Physics 2023-12-12 Rachel K. Luu , Markus J. Buehler