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The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Large language models (LLMs) perform strongly on many language tasks but still struggle with complex multi-step reasoning across disciplines. Existing reasoning datasets often lack disciplinary breadth, reasoning depth, and diversity, as…

Computation and Language · Computer Science 2026-02-03 Weize Liu , Yongchi Zhao , Yijia Luo , Mingyu Xu , Jiaheng Liu , Yanan Li , Xiguo Hu , Zhiqi Bai , Yuchi Xu , Wenbo Su , Bo Zheng

Effective document reranking is essential for improving search relevance across diverse applications. While Large Language Models (LLMs) excel at reranking due to their deep semantic understanding and reasoning, their high computational…

Computation and Language · Computer Science 2025-10-03 Dimitar Peshevski , Kiril Blazhevski , Martin Popovski , Gjorgji Madjarov

Autonomous agents powered by large language models (LLMs) promise to accelerate scientific discovery end-to-end, but rigorously evaluating their capacity for verifiable discovery remains a central challenge. Existing benchmarks face a…

Artificial Intelligence · Computer Science 2026-02-04 Zhen Wang , Fan Bai , Zhongyan Luo , Jinyan Su , Kaiser Sun , Xinle Yu , Jieyuan Liu , Kun Zhou , Claire Cardie , Mark Dredze , Eric P. Xing , Zhiting Hu

The task of chemical reaction predictions (CRPs) plays a pivotal role in advancing drug discovery and material science. However, its effectiveness is constrained by the vast and uncertain chemical reaction space and challenges in capturing…

Machine Learning · Computer Science 2024-04-16 Pengfei Liu , Jun Tao , Zhixiang Ren

The large set of technical documentation of legacy accelerator systems, coupled with the retirement of experienced personnel, underscores the urgent need for efficient methods to preserve and transfer specialized knowledge. This paper…

Information Retrieval · Computer Science 2025-09-03 Qing Dai , Rasmus Ischebeck , Maruisz Sapinski , Adam Grycner

The rise of large language models (LLMs) has made natural language-driven route planning an emerging research area that encompasses rich user objectives. Current research exhibits two distinct approaches: direct route planning using…

Artificial Intelligence · Computer Science 2025-09-17 Liangqi Yuan , Dong-Jun Han , Christopher G. Brinton , Sabine Brunswicker

We propose a methodology that combines several advanced techniques in Large Language Model (LLM) retrieval to support the development of robust, multi-source question-answer systems. This methodology is designed to integrate information…

Artificial Intelligence · Computer Science 2024-12-25 Antony Seabra , Claudio Cavalcante , Joao Nepomuceno , Lucas Lago , Nicolaas Ruberg , Sergio Lifschitz

In the current era of big data, extracting deep insights from massive, heterogeneous, and complexly associated multi-dimensional data has become a significant challenge. Large Language Models (LLMs) perform well in natural language…

Artificial Intelligence · Computer Science 2025-11-21 Xi Wang , Xianyao Ling , Kun Li , Gang Yin , Liang Zhang , Jiang Wu , Jun Xu , Fu Zhang , Wenbo Lei , Annie Wang , Peng Gong

Large Language Models (LLMs) can be fine-tuned on domain-specific data to enhance their performance in specialized fields. However, such data often contains numerous low-quality samples, necessitating effective data processing (DP). In…

Machine Learning · Computer Science 2026-05-08 Wei Huang , Anda Cheng , Yinggui Wang , Lei Wang , Tao Wei

Recent advances in large language models (LLMs) have given rise to powerful coding agents, making it possible for code assistants to evolve into code engineers. However, existing methods still face significant challenges in achieving…

Software Engineering · Computer Science 2025-12-10 Zongwei Li , Zhonghang Li , Zirui Guo , Xubin Ren , Chao Huang

While inorganic retrosynthesis planning is essential in the field of chemical science, the application of machine learning in this area has been notably less explored compared to organic retrosynthesis planning. In this paper, we propose…

Machine Learning · Computer Science 2025-10-14 Heewoong Noh , Namkyeong Lee , Gyoung S. Na , Chanyoung Park

This study addresses the challenges of tracking and analyzing students' learning trajectories, particularly the issue of inadequate knowledge coverage in course assessments. Traditional assessment tools often fail to fully cover course…

Computers and Society · Computer Science 2025-04-17 Yu-Hxiang Chen , Ju-Shen Huang , Jia-Yu Hung , Chia-Kai Chang

Predicting reactants from a specified core product stands as a fundamental challenge within organic synthesis, termed retrosynthesis prediction. Recently, semi-template-based methods and graph-edits-based methods have achieved good…

Quantitative Methods · Quantitative Biology 2024-02-13 Zixun Lan , Binjie Hong , Jiajun Zhu , Zuo Zeng , Zhenfu Liu , Limin Yu , Fei Ma

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Scientific research increasingly relies on specialized computational tools, yet effectively utilizing these tools demands substantial domain expertise. While Large Language Models (LLMs) show promise in tool automation, they struggle to…

Artificial Intelligence · Computer Science 2025-07-29 Keyan Ding , Jing Yu , Junjie Huang , Yuchen Yang , Qiang Zhang , Huajun Chen

The combination of LLM agents with external tools enables models to solve complex tasks beyond their knowledge base. Human-designed tools are inflexible and restricted to solutions within the scope of pre-existing tools created by experts.…

Artificial Intelligence · Computer Science 2025-11-18 Mohd Ariful Haque , Justin Williams , Sunzida Siddique , Md. Hujaifa Islam , Hasmot Ali , Kishor Datta Gupta , Roy George

The exponential growth of scientific literature poses unprecedented challenges for researchers attempting to synthesize knowledge across rapidly evolving fields. We present \textbf{Agentic AutoSurvey}, a multi-agent framework for automated…

Information Retrieval · Computer Science 2025-09-24 Yixin Liu , Yonghui Wu , Denghui Zhang , Lichao Sun

A key challenge in artificial intelligence is the creation of systems capable of autonomously advancing scientific understanding by exploring novel domains, identifying complex patterns, and uncovering previously unseen connections in vast…

Artificial Intelligence · Computer Science 2024-09-10 Alireza Ghafarollahi , Markus J. Buehler

Modern retrieval systems do not rely on a single ranking model to construct their rankings. Instead, they generally take a cascading approach where a sequence of ranking models are applied in multiple re-ranking stages. Thereby, they…

Information Retrieval · Computer Science 2025-04-17 Harrie Oosterhuis , Rolf Jagerman , Zhen Qin , Xuanhui Wang
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