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Conversational Machine Reading (CMR) requires answering a user's initial question through multi-turn dialogue interactions based on a given document. Although there exist many effective methods, they largely neglected the alignment between…

Computation and Language · Computer Science 2023-10-23 Yangyang Luo , Shiyu Tian , Caixia Yuan , Xiaojie Wang

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Clinical language models (LMs) are increasingly applied to support clinical risk prediction from free-text notes, yet their uncertainty estimates often remain poorly calibrated and clinically unreliable. In this work, we propose Clinical…

Computation and Language · Computer Science 2026-04-27 Sizhe Wang , Ziqi Xu , Claire Najjuuko , Charles Alba , Chenyang Lu

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Machine Learning · Computer Science 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Previous multimodal sentence representation learning methods have achieved impressive performance. However, most approaches focus on aligning images and text at a coarse level, facing two critical challenges:cross-modal misalignment bias…

Computation and Language · Computer Science 2025-07-02 Kang He , Yuzhe Ding , Haining Wang , Fei Li , Chong Teng , Donghong Ji

Medication recommendations have become an important task in the healthcare domain, especially in measuring the accuracy and safety of medical dialogue systems (MDS). Different from the recommendation task based on electronic health records…

Computation and Language · Computer Science 2025-05-20 Jialun Zhong , Yanzeng Li , Sen Hu , Yang Zhang , Teng Xu , Lei Zou

Nuclear magnetic resonance (NMR) spectroscopy provides an experimental readout of local chemical environments, but its use in molecular representation learning has been constrained by heterogeneous data and incomplete atom-level…

Chemical Physics · Physics 2026-05-12 Jiebin Fang , Zidi Yan , Churu Mao , Yongjun Jiang , Xinyi Tang , Lei Miao , Dan Lu , Yun Huang , Wanjing Ding , Zhongjun Ma

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Medical vision-language models show strong potential for joint reasoning over medical images and clinical text, but their performance often degrades under domain shift caused by variations in imaging devices, acquisition protocols, and…

Machine Learning · Computer Science 2026-02-23 Melika Filvantorkaman , Mohsen Piri

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

The integration of large language models (LLMs) into medical practice offers transformative potential, yet their real-world clinical applicability remains constrained by critical alignment issues: (1) a misalignment between static…

Artificial Intelligence · Computer Science 2025-12-05 Yongnan Jin , Xurui Li , Feng Cao , Liucun Gao , Juanjuan Yao

In modern industry systems like multi-turn chat agents, Text-to-SQL technology bridges natural language (NL) questions and database (DB) querying. The conversion of tabular DB results into NL representations (NLRs) enables the chat-based…

Computation and Language · Computer Science 2025-10-29 Jyotika Singh , Weiyi Sun , Amit Agarwal , Viji Krishnamurthy , Yassine Benajiba , Sujith Ravi , Dan Roth

Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming…

Biomolecules · Quantitative Biology 2025-03-06 Jiajun Yu , Yizhen Zheng , Huan Yee Koh , Shirui Pan , Tianyue Wang , Haishuai Wang

Current methods for Video Moment Retrieval (VMR) struggle to align complex situations involving specific environmental details, character descriptions, and action narratives. To tackle this issue, we propose a Large Language Model-guided…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Weijia Liu , Bo Miao , Jiuxin Cao , Xuelin Zhu , Bo Liu , Mehwish Nasim , Ajmal Mian

Recent studies have explored the use of large language models (LLMs) in psychotherapy; however, text-based cognitive behavioral therapy (CBT) models often struggle with client resistance, which can weaken therapeutic alliance. To address…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Subin Kim , Hoonrae Kim , Jihyun Lee , Yejin Jeon , Gary Geunbae Lee

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

Computation and Language · Computer Science 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

MLLMs have recently become a focal point in the field of artificial intelligence research. Building on the strong capabilities of LLMs, MLLMs are adept at addressing complex multi-modal tasks. With the release of GPT-4, MLLMs have gained…

Machine Learning · Computer Science 2025-05-01 Jiarui Ye , Hao Tang

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Large language models (LLMs) have become increasingly useful computational models of human language processing, but it remains unclear whether vision-language learning makes text representations more human-like during natural reading. Here,…

Computation and Language · Computer Science 2026-05-28 Jinzhou Wu , Zhengwu Ma , Jixing Li , Baoping Tang , Zitong Lu