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Feature selection techniques are essential for high-dimensional data analysis. In the last two decades, their popularity has been fuelled by the increasing availability of high-throughput biomolecular data where high-dimensionality is a…

Quantitative Methods · Quantitative Biology 2024-01-18 Pengyi Yang , Hao Huang , Chunlei Liu

Feature selection represents a measure to reduce the complexity of high-dimensional datasets and gain insights into the systematic variation in the data. This aspect is of specific importance in domains that rely on model interpretability,…

Machine Learning · Computer Science 2022-09-07 Anna Jenul , Stefan Schrunner , Jürgen Pilz , Oliver Tomic

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

Analysis of high-dimensional data is currently a popular field of research, thanks to many applications e.g. in genetics (DNA data in genomewide association studies), spectrometry or web analysis. At the same time, the type of problems that…

Methodology · Statistics 2018-05-25 Jozef Jakubik

The development of medical vision-language foundation models has attracted significant attention in the field of medicine and healthcare due to their promising prospect in various clinical applications. While previous studies have commonly…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Weijian Huang , Cheng Li , Hong-Yu Zhou , Jiarun Liu , Hao Yang , Yong Liang , Guangming Shi , Hairong Zheng , Shanshan Wang

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Feature selection, as a data preprocessing strategy, has been proven to be effective and efficient in preparing data (especially high-dimensional data) for various data mining and machine learning problems. The objectives of feature…

Machine Learning · Computer Science 2018-08-28 Jundong Li , Kewei Cheng , Suhang Wang , Fred Morstatter , Robert P. Trevino , Jiliang Tang , Huan Liu

The healthcare sector is an important pillar of every community, numerous research studies have been carried out in this context to optimize medical processes and improve care quality and facilitate patient management. In this article we…

Machine Learning · Computer Science 2023-04-04 Chaimae Taoussi , Imad Hafidi , Abdelmoutalib Metrane

To solve complex real-world problems, heuristics and concept-based approaches can be used in order to incorporate information into the problem. In this study, a concept-based approach called variable functioning Fx is introduced to reduce…

Computational Engineering, Finance, and Science · Computer Science 2022-05-17 Amir H Gandomi , Kalyanmoy Deb , Ronald C Averill , Shahryar Rahnamayan , Mohammad Nabi Omidvar

Feature selection is a critical step in the analysis of high-dimensional data, where the number of features often vastly exceeds the number of samples. Effective feature selection not only improves model performance and interpretability but…

Machine Learning · Computer Science 2025-01-27 Raquel Espinosa , Gracia Sánchez , José Palma , Fernando Jiménez

An individualized treatment rule (ITR) is a decision rule that aims to improve individual patients health outcomes by recommending optimal treatments according to patients specific information. In observational studies, collected data may…

Methodology · Statistics 2023-10-03 Zeyu Bian , Erica EM Moodie , Susan M Shortreed , Sylvie D Lambert , Sahir Bhatnagar

In the era of big data, analysts usually explore various statistical models or machine learning methods for observed data in order to facilitate scientific discoveries or gain predictive power. Whatever data and fitting procedures are…

Machine Learning · Statistics 2018-10-24 Jie Ding , Vahid Tarokh , Yuhong Yang

We propose a method for variable selection in multiple regression with random predictors. This method is based on a criterion that permits to reduce the variable selection problem to a problem of estimating suitable permutation and…

Statistics Theory · Mathematics 2015-06-29 Alban Mbina Mbina , Guy Martial Nkiet , Assi Nguessan

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

Methodology · Statistics 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

Statistical learning evolves quickly with more and more sophisticated models proposed to incorporate the complicated data structure from modern scientific and business problems. Varying index coefficient models extend varying coefficient…

Statistics Theory · Mathematics 2019-03-05 Li Jialiang , Lv Jing

We propose generalized additive partial linear models for complex data which allow one to capture nonlinear patterns of some covariates, in the presence of linear components. The proposed method improves estimation efficiency and increases…

Statistics Theory · Mathematics 2014-05-26 Li Wang , Lan Xue , Annie Qu , Hua Liang

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

We propose a new method for input variable selection in nonlinear regression. The method is embedded into a kernel regression machine that can model general nonlinear functions, not being a priori limited to additive models. This is the…

Machine Learning · Computer Science 2018-09-05 Magda Gregorová , Jason Ramapuram , Alexandros Kalousis , Stéphane Marchand-Maillet