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The application of machine learning to transcriptomics data has led to significant advances in cancer research. However, the high dimensionality and complexity of RNA sequencing (RNA-seq) data pose significant challenges in pan-cancer…

Genomics · Quantitative Biology 2024-08-15 Jong Hyun Kim , Jongseong Jang

Brain tumors remain a critical global health challenge, necessitating advancements in diagnostic techniques and treatment methodologies. A tumor or its recurrence often needs to be identified in imaging studies and differentiated from…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Shashidhar Reddy Javaji , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

Ensemble classification is an emerging approach to land cover mapping whereby the final classification output is a result of a consensus of classifiers. Intuitively, an ensemble system should consist of base classifiers which are diverse…

Machine Learning · Computer Science 2008-11-14 A. Gidudu , B. Abe , T. Marwala

There is a keen interest in characterizing variation in the microbiome across cancer patients, given increasing evidence of its important role in determining treatment outcomes. Here our goal is to discover subgroups of patients with…

Applications · Statistics 2022-12-06 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Robert Jenq , Christine Peterson

Detailed phenotype information is fundamental to accurate diagnosis and risk estimation of diseases. As a rich source of phenotype information, electronic health records (EHRs) promise to empower diagnostic variant interpretation. However,…

Machine Learning · Computer Science 2023-04-28 Shenghan Zhang , Haoxuan Li , Ruixiang Tang , Sirui Ding , Laila Rasmy , Degui Zhi , Na Zou , Xia Hu

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Richard J. Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Jana Lipkova , Muhammad Shaban , Maha Shady , Mane Williams , Bumjin Joo , Zahra Noor , Faisal Mahmood

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

Artificial Intelligence · Computer Science 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

Cancer has become one of the most widespread diseases in the world. Specifically, breast cancer is diagnosed more often than any other type of cancer. However, breast cancer patients and their individual tumors are often unique. Identifying…

Quantitative Methods · Quantitative Biology 2016-12-06 Chenzhe Qian

Accurate classification of brain tumors from magnetic resonance imaging (MRI) plays a critical role in early diagnosis and effective treatment planning. In this study, we propose a deep learning framework based on Vision Transformers (ViT)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Faisal Ahmed

To address the issues of limited samples, time-consuming feature design, and low accuracy in detection and classification of breast cancer pathological images, a breast cancer image classification model algorithm combining deep learning and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Weimin Wang , Yufeng Li , Xu Yan , Mingxuan Xiao , Min Gao

This paper presents a novel approach to accurately classify the hallmarks of cancer, which is a crucial task in cancer research. Our proposed method utilizes the Bidirectional Encoder Representations from Transformers (BERT) architecture,…

Computation and Language · Computer Science 2023-06-08 Sultan Zavrak , Seyhmus Yilmaz

We propose a novel methodology for feature screening in clustering massive datasets, in which both the number of features and the number of observations can potentially be very large. Taking advantage of a fusion penalization based convex…

Methodology · Statistics 2017-10-05 Trambak Banerjee , Gourab Mukherjee , Peter Radchenko

Breast cancer classification stands as a pivotal pillar in ensuring timely diagnosis and effective treatment. This study with histopathological images underscores the profound significance of harnessing the synergistic capabilities of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Sambit Mallick , Snigdha Paul , Anindya Sen

The application of machine learning methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer…

Machine Learning · Computer Science 2024-09-02 Fadi Alharbi , Aleksandar Vakanski , Murtada K. Elbashir , Mohanad Mohammed

This work presents a novel approach for selecting the optimal ensemble-based classification method and features with a primarly focus on achieving generalization, based on the state-of-the-art, to provide diagnostic support for Sickle Cell…

Machine Learning · Computer Science 2026-01-21 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Jose Maria Buades Rubio

Acute lymphoblastic leukemia (ALL) is the most malignant form of leukemia and the most common cancer in adults and children. Traditionally, leukemia is diagnosed by analyzing blood and bone marrow smears under a microscope, with additional…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Maksuda Akter , Rabea Khatun , Md Manowarul Islam

Brain tumor classification using MRI images is critical in medical diagnostics, where early and accurate detection significantly impacts patient outcomes. While recent advancements in deep learning (DL), particularly CNNs, have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Priyam Ganguly , Akhilbaran Ghosh

Computer-aided detection (CAD) of benign and malignant breast lesions becomes increasingly essential in breast ultrasound (US) imaging. The CAD systems rely on imaging features identified by the medical experts for their performance,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-18 Sampa Misra , Seungwan Jeon , Ravi Managuli , Seiyon Lee , Gyuwon Kim , Seungchul Lee , Richard G Barr , Chulhong Kim

As Deep Convolutional Neural Networks (DCNNs) have shown robust performance and results in medical image analysis, a number of deep-learning-based tumor detection methods were developed in recent years. Nowadays, the automatic detection of…

Computer Vision and Pattern Recognition · Computer Science 2020-02-12 Zhengdong Zhang , Shuai Li , Ziyang Wang , Yun Lu

In statistics and machine learning, feature selection is the process of picking a subset of relevant attributes for utilizing in a predictive model. Recently, rough set-based feature selection techniques, that employ feature dependency to…

Machine Learning · Computer Science 2020-03-30 Seyedeh Faezeh Farahbakhshian , Milad Taleby Ahvanooey