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Microarray technology is known as one of the most important tools for collecting DNA expression data. This technology allows researchers to investigate and examine types of diseases and their origins. However, microarray data are often…

Quantitative Methods · Quantitative Biology 2021-01-05 Babak Nouri-Moghaddam , Mehdi Ghazanfari , Mohammad Fathian

Pancreatic cancer, characterized by its notable prevalence and mortality rates, demands accurate lesion delineation for effective diagnosis and therapeutic interventions. The generalizability of extant methods is frequently compromised due…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Jun Li , Yijue Zhang , Haibo Shi , Minhong Li , Qiwei Li , Xiaohua Qian

Gliomas are brain tumours with a high mortality rate. There are various grades and sub-types of this tumour, and the treatment procedure varies accordingly. Clinicians and oncologists diagnose and categorise these tumours based on visual…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Azam Hamidinekoo , Tomasz Pieciak , Maryam Afzali , Otar Akanyeti , Yinyin Yuan

It is increasingly common clinically for cancer specimens to be examined using techniques that identify somatic mutations. In principle these mutational profiles can be used to diagnose the tissue of origin, a critical task for the 3-5% of…

Methodology · Statistics 2020-07-14 Saptarshi Chakraborty , Colin B. Begg , Ronglai Shen

Accurate sample classification using transcriptomics data is crucial for advancing personalized medicine. Achieving this goal necessitates determining a suitable sample size that ensures adequate statistical power without undue resource…

Methodology · Statistics 2024-09-11 Yunhui Qi , Xinyi Wang , Li-Xuan Qin

Breast cancer is one of the most common cancers among women globally, with early diagnosis and precise classification being crucial. With the advancement of deep learning and computer vision, the automatic classification of breast tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Jiacheng Hao , Yiqing Liu , Siqi Zeng , Yonghong He

Determining lymphoma subtypes is a crucial step for better patient treatment targeting to potentially increase their survival chances. In this context, the existing gold standard diagnosis method, which relies on gene expression technology,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Marianne Petit , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Prostate cancer is a highly prevalent cancer and ranks as the second leading cause of cancer-related deaths in men globally. Recently, the utilization of multi-modality transrectal ultrasound (TRUS) has gained significant traction as a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Hong Wu , Juan Fu , Hongsheng Ye , Yuming Zhong , Xuebin Zou , Jianhua Zhou , Yi Wang

Breast cancer is the most common malignancy affecting women worldwide and is notable for its morphologic and biologic diversity, with varying risks of recurrence following treatment. The Oncotype DX Breast Recurrence Score test is an…

Nuclei segmentation and classification provide an essential basis for tumor immune microenvironment analysis. The previous nuclei segmentation and classification models require splitting large images into smaller patches for training,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Ye Zhang , Zijie Fang , Yifeng Wang , Lingbo Zhang , Xianchao Guan , Yongbing Zhang

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Breast cancer is the most common cancer among women both in developed and developing countries. Early detection and diagnosis of breast cancer may reduce its mortality and improve the quality of life. Computer-aided detection (CADx) and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-23 Sokratis Makrogiannis , Chelsea E. Harris , Keni Zheng

Reliable classification of benign and malignant lesions in breast ultrasound images can provide an effective and relatively low cost method for early diagnosis of breast cancer. The accuracy of the diagnosis is however highly dependent on…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Elham Yousef Kalaf , Ata Jodeiri , Seyed Kamaledin Setarehdan , Ng Wei Lin , Kartini Binti Rahman , Nur Aishah Taib , Sarinder Kaur Dhillon

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

As the application of deep learning in dermatology continues to grow, the recognition of melanoma has garnered significant attention, demonstrating potential for improving diagnostic accuracy. Despite advancements in image classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rujosh Polma , Krishnan Menon Iyer

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

Quantitative Methods · Quantitative Biology 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

The effective management of brain tumors relies on precise typing, subtyping, and grading. This study advances patient care with findings from rigorous multiple instance learning experimentations across various feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Ekansh Chauhan , Amit Sharma , Megha S Uppin , C. V. Jawahar , P. K. Vinod

The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in…

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