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Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

Machine Learning · Computer Science 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi

Discovery of diagnostic and prognostic molecular markers is important and actively pursued the research field in cancer research. For complex diseases, this process is often performed using Machine Learning. The current study compares two…

Genomics · Quantitative Biology 2020-04-30 Aneta Polewko-Klim , Witold R. Rudnicki

To improve patient survival and treatment outcomes, early diagnosis of brain tumors is an essential task. It is a difficult task to evaluate the magnetic resonance imaging (MRI) images manually. Thus, there is a need for digital methods for…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ginni Garg , Ritu Garg

Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…

Genomics · Quantitative Biology 2018-10-10 Zexian Zeng , Andy Vo , Chengsheng Mao , Susan E Clare , Seema A Khan , Yuan Luo

Magnetic Resonance Imaging (MRI) is widely recognized as the most reliable tool for detecting tumors due to its capability to produce detailed images that reveal their presence. However, the accuracy of diagnosis can be compromised when…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zahid Ullah , Dragan Pamucar , Jihie Kim

We utilized abundant transcriptomic data for the primary classes of brain cancers to study the feasibility of separating all of these diseases simultaneously based on molecular data alone. These signatures were based on a new method…

Quantitative Methods · Quantitative Biology 2013-08-05 Jaeyun Sung , Pan-Jun Kim , Shuyi Ma , Cory C. Funk , Andrew T. Magis , Yuliang Wang , Leroy Hood , Donald Geman , Nathan D. Price

The transcriptomics of cancer tumors are characterized with tens of thousands of gene expression features. Patient prognosis or tumor stage can be assessed by machine learning techniques like supervised classification tasks given a gene…

Machine Learning · Computer Science 2020-04-13 Martin Palazzo , Patricio Yankilevich , Pierre Beauseroy

The accurate classification of brain tumors from MRI scans is essential for effective diagnosis and treatment planning. This paper presents a weighted ensemble learning approach that combines deep learning and traditional machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Ha Anh Vu

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

In this work, we study and analyze different feature selection algorithms that can be used to classify cancer subtypes in case of highly varying high-dimensional data. We apply three different feature selection methods on five different…

Machine Learning · Computer Science 2021-10-01 Vaibhav Sinha , Siladitya Dash , Nazma Naskar , Sk Md Mosaddek Hossain

Gene expression analysis is a critical method for cancer classification, enabling precise diagnoses through the identification of unique molecular signatures associated with various tumors. Identifying cancer-specific genes from gene…

Quantitative Methods · Quantitative Biology 2024-10-11 Farzana Tabassum , Sabrina Islam , Siana Rizwan , Masrur Sobhan , Tasnim Ahmed , Sabbir Ahmed , Tareque Mohmud Chowdhury

Various approaches to gene selection for cancer classification based on microarray data can be found in the literature and they may be grouped into two categories: univariate methods and multivariate methods. Univariate methods look at each…

Quantitative Methods · Quantitative Biology 2015-06-18 Min Xu , Rudy Setiono

The aim of this work is to propose an ensemble of descriptors for Melanoma Classification, whose performance has been evaluated on validation and test datasets of the melanoma challenge 2018. The system proposed here achieves a strong…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Loris Nanni , Alessandra Lumini , Stefano Ghidoni

We present a nonparametric Bayesian method for disease subtype discovery in multi-dimensional cancer data. Our method can simultaneously analyse a wide range of data types, allowing for both agreement and disagreement between their…

Genomics · Quantitative Biology 2013-04-16 Richard S. Savage , Zoubin Ghahramani , Jim E. Griffin , Paul Kirk , David L. Wild

Molecular data from tumor profiles is high dimensional. Tumor profiles can be characterized by tens of thousands of gene expression features. Due to the size of the gene expression feature set machine learning methods are exposed to noisy…

Machine Learning · Computer Science 2020-07-14 Martin Palazzo , Pierre Beauseroy , Patricio Yankilevich

Pan-cancer classification using transcriptomic (RNA-Seq) data can inform tumor subtyping and therapy selection, but is challenging due to extremely high dimensionality and limited sample sizes. In this study, we propose a novel deep…

Genomics · Quantitative Biology 2025-08-06 Vinil Polepalli

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Accurate brain tumor classification is crucial in medical imaging to ensure reliable diagnosis and effective treatment planning. This study introduces a novel double ensembling framework that synergistically combines pre-trained deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Zahid Ullah , Jihie Kim

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

Motivation: Biomarker discovery from high-dimensional data is a crucial problem with enormous applications in biology and medicine. It is also extremely challenging from a statistical viewpoint, but surprisingly few studies have…

Quantitative Methods · Quantitative Biology 2012-09-17 Anne-Claire Haury , Pierre Gestraud , Jean-Philippe Vert
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