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Protein structures are important for understanding their functions and interactions. Currently, many protein structure prediction methods are enriching the structure database. Discriminating the origin of structures is crucial for…

Biomolecules · Quantitative Biology 2024-10-24 Wenrui Gou , Wenhui Ge , Yang Tan , Mingchen Li , Guisheng Fan , Huiqun Yu

Classical models for supervised machine learning, such as decision trees, are efficient and interpretable predictors, but their quality is highly dependent on the particular choice of input features. Although neural networks can learn…

Machine Learning · Computer Science 2025-10-17 Gabriel Poesia , Georgia Gabriela Sampaio

Protein function annotation is an important yet challenging task in biology. Recent deep learning advancements show significant potential for accurate function prediction by learning from protein sequences and structures. Nevertheless,…

Biomolecules · Quantitative Biology 2024-02-14 Zuobai Zhang , Jiarui Lu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

We propose AttentionMixer, a unified deep learning framework for multimodal detection of brain edema that combines structural head CT (HCT) with routine clinical metadata. While HCT provides rich spatial information, clinical variables such…

Real-time object detection is crucial for real-world applications as it requires high accuracy with low latency. While Detection Transformers (DETR) have demonstrated significant performance improvements, current real-time DETR models are…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Jiannan Huang , Aditya Kane , Fengzhe Zhou , Yunchao Wei , Humphrey Shi

In recent era prediction of enzyme class from an unknown protein is one of the challenging tasks in bioinformatics. Day to day the number of proteins is increases as result the prediction of enzyme class gives a new opportunity to…

Machine Learning · Computer Science 2019-01-21 Chhote Lal Prasad Gupta , Anand Bihari , Sudhakar Tripathi

In electroencephalogram (EEG) recordings, the presence of interictal epileptiform discharges (IEDs) serves as a critical biomarker for seizures or seizure-like events.Detecting IEDs can be difficult; even highly trained experts disagree on…

Named Entity Recognition (NER) aims to extract and classify entity mentions in the text into pre-defined types (e.g., organization or person name). Recently, many works have been proposed to shape the NER as a machine reading comprehension…

Computation and Language · Computer Science 2023-09-21 Yibo Wang , Wenting Zhao , Yao Wan , Zhongfen Deng , Philip S. Yu

There is a growing concern about typically opaque decision-making with high-performance machine learning algorithms. Providing an explanation of the reasoning process in domain-specific terms can be crucial for adoption in risk-sensitive…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Aditya Chattopadhyay , Stewart Slocum , Benjamin D. Haeffele , Rene Vidal , Donald Geman

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Event-based cameras (EBCs) have emerged as a bio-inspired alternative to traditional cameras, offering advantages in power efficiency, temporal resolution, and high dynamic range. However, the development of image analysis methods for EBCs…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Dmitrii Torbunov , Yihui Ren , Animesh Ghose , Odera Dim , Yonggang Cui

The diverse nature of protein prediction tasks has traditionally necessitated specialized models, hindering the development of broadly applicable and computationally efficient Protein Language Models (PLMs). In this work, we introduce…

One of the major challenges in machine learning nowadays is to provide predictions with not only high accuracy but also user-friendly explanations. Although in recent years we have witnessed increasingly popular use of deep neural networks…

Machine Learning · Computer Science 2019-07-24 Yao Ming , Panpan Xu , Huamin Qu , Liu Ren

Effective representations of protein sequences are widely recognized as a cornerstone of machine learning-based protein design. Yet, protein bioengineering poses unique challenges for sequence representation, as experimental datasets…

Quantitative Methods · Quantitative Biology 2026-04-07 Ana F. Rodrigues , Lucas Ferraz , Laura Balbi , Pedro Giesteira Cotovio , Catia Pesquita

Protein language models (PLMs) have transformed sequence-based protein analysis, yet most applications rely only on final-layer embeddings, which may overlook biologically meaningful information encoded in earlier layers. We systematically…

Quantitative Methods · Quantitative Biology 2025-12-02 Ajit Kumar , IndraPrakash Jha

Prototype-based methods are of the particular interest for domain specialists and practitioners as they summarize a dataset by a small set of representatives. Therefore, in a classification setting, interpretability of the prototypes is as…

Machine Learning · Computer Science 2019-11-12 Babak Hosseini , Barbara Hammer

As machine learning models are increasingly deployed in high-stakes domains, the need for interpretability has grown to meet strict regulatory and accountability constraints. Despite this interest, systematic evaluations of inherently…

Machine Learning · Computer Science 2026-03-27 Mattia Billa , Giovanni Orlandi , Veronica Guidetti , Federica Mandreoli

The astounding performance of transformers in natural language processing (NLP) has motivated researchers to explore their applications in computer vision tasks. DEtection TRansformer (DETR) introduces transformers to object detection tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Tahira Shehzadi , Khurram Azeem Hashmi , Didier Stricker , Muhammad Zeshan Afzal

Transformer is a ubiquitous model for natural language processing and has attracted wide attentions in computer vision. The attention maps are indispensable for a transformer model to encode the dependencies among input tokens. However,…

Machine Learning · Computer Science 2021-02-26 Yujing Wang , Yaming Yang , Jiangang Bai , Mingliang Zhang , Jing Bai , Jing Yu , Ce Zhang , Gao Huang , Yunhai Tong

In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…

Machine Learning · Computer Science 2022-04-05 Pedro Sandoval-Segura , Wallace Lawson