English
Related papers

Related papers: Interpretable Enzyme Function Prediction via Resid…

200 papers

Generalizable protein function prediction is increasingly constrained by the growing mismatch between exponentially expanding sequences of environmental proteins and the comparatively slow accumulation of experimentally verified functional…

Quantitative Methods · Quantitative Biology 2026-02-27 Ashley Babjac , Adrienne Hoarfrost

We introduce ProtoSeg, a novel model for interpretable semantic image segmentation, which constructs its predictions using similar patches from the training set. To achieve accuracy comparable to baseline methods, we adapt the mechanism of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Mikołaj Sacha , Dawid Rymarczyk , Łukasz Struski , Jacek Tabor , Bartosz Zieliński

The Euler Characteristic Transform (ECT) has proven to be a powerful representation, combining geometrical and topological characteristics of shapes and graphs. However, the ECT was hitherto unable to learn task-specific representations. We…

Machine Learning · Computer Science 2024-03-20 Ernst Roell , Bastian Rieck

During the past decade, with the significant progress of computational power as well as ever-rising data availability, deep learning techniques became increasingly popular due to their excellent performance on computer vision problems. The…

Quantitative Methods · Quantitative Biology 2017-07-20 Afshine Amidi , Shervine Amidi , Dimitrios Vlachakis , Vasileios Megalooikonomou , Nikos Paragios , Evangelia I. Zacharaki

Predicting diagnoses from Electronic Health Records (EHRs) is an important medical application of multi-label learning. We propose a convolutional residual model for multi-label classification from doctor notes in EHR data. A given patient…

Machine Learning · Statistics 2018-08-10 Xinyuan Zhang , Ricardo Henao , Zhe Gan , Yitong Li , Lawrence Carin

Image classification models have achieved satisfactory performance on many datasets, sometimes even better than human. However, The model attention is unclear since the lack of interpretability. This paper investigates the fidelity and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Wenjia Xu , Jiuniu Wang , Yang Wang , Guangluan Xu , Wei Dai , Yirong Wu

Clothing segmentation and fine-grained attribute recognition are challenging tasks at the crossing of computer vision and fashion, which segment the entire ensemble clothing instances as well as recognize detailed attributes of the clothing…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Hao Tian , Yu Cao , P. Y. Mok

Detecting and segmenting object instances is a common task in biomedical applications. Examples range from detecting lesions on functional magnetic resonance images, to the detection of tumours in histopathological images and extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Tim Prangemeier , Christoph Reich , Heinz Koeppl

Existing methods enhance the training of detection transformers by incorporating an auxiliary one-to-many assignment. In this work, we treat the model as a multi-task framework, simultaneously performing one-to-one and one-to-many…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Chang-Bin Zhang , Yujie Zhong , Kai Han

Enzymes, with their specific catalyzed reactions, are necessary for all aspects of life, enabling diverse biological processes and adaptations. Predicting enzyme functions is essential for understanding biological pathways, guiding drug…

Machine Learning · Computer Science 2024-10-02 Chenqing Hua , Bozitao Zhong , Sitao Luan , Liang Hong , Guy Wolf , Doina Precup , Shuangjia Zheng

Interpretability is an important aspect of the trustworthiness of a model's predictions. Transformer's predictions are widely explained by the attention weights, i.e., a probability distribution generated at its self-attention unit (head).…

Computation and Language · Computer Science 2021-06-03 Rishabh Bhardwaj , Navonil Majumder , Soujanya Poria , Eduard Hovy

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Machine Learning-guided solutions for protein learning tasks have made significant headway in recent years. However, success in scientific discovery tasks is limited by the accessibility of well-defined and labeled in-domain data. To tackle…

Machine Learning · Computer Science 2023-01-06 Ria Vinod , Pin-Yu Chen , Payel Das

Sequence classification is the task of predicting a class label given a sequence of observations. In many applications such as healthcare monitoring or intrusion detection, early classification is crucial to prompt intervention. In this…

Machine Learning · Computer Science 2020-10-07 Maayan Shvo , Andrew C. Li , Rodrigo Toro Icarte , Sheila A. McIlraith

Retrosynthesis prediction aims to infer the reactant molecule based on a given product molecule, which is a fundamental task in chemical synthesis. However, existing models rely on static pattern-matching paradigm, which limits their…

Machine Learning · Computer Science 2025-12-08 Xinyi Li , Sai Wang , Yutian Lin , Yu Wu , Yi Yang

Introduction: The extracellular matrix (ECM) is a networkof proteins and carbohydrates that has a structural and bio-chemical function. The ECM plays an important role in dif-ferentiation, migration and signaling. Several studies…

Quantitative Methods · Quantitative Biology 2022-02-17 Mohamed Ghafoor , Anh Nguyen

Predicting faults before they occur helps to avoid potential safety hazards. Furthermore, planning the required maintenance actions in advance reduces operation costs. In this article, the focus is on electrochemical cells. In order to…

Machine Learning · Computer Science 2020-07-28 Daniel Buades Marcos , Soumaya Yacout , Said Berriah

Multimodal emotion recognition is an important research topic in artificial intelligence, whose main goal is to integrate multimodal clues to identify human emotional states. Current works generally assume accurate labels for benchmark…

The Transformer-based detectors (i.e., DETR) have demonstrated impressive performance on end-to-end object detection. However, transferring DETR to different data distributions may lead to a significant performance degradation. Existing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Peidong Jia , Jiaming Liu , Senqiao Yang , Jiarui Wu , Xiaodong Xie , Shanghang Zhang

With the proliferation of models for natural language processing tasks, it is even harder to understand the differences between models and their relative merits. Simply looking at differences between holistic metrics such as accuracy, BLEU,…

Computation and Language · Computer Science 2020-12-10 Jinlan Fu , Pengfei Liu , Graham Neubig