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Uncertainty estimation in deep learning has become a leading research field in medical image analysis due to the need for safe utilisation of AI algorithms in clinical practice. Most approaches for uncertainty estimation require sampling…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Kaisar Kushibar , Víctor Manuel Campello , Lidia Garrucho Moras , Akis Linardos , Petia Radeva , Karim Lekadir

Finely-tuned enzymatic pathways control cellular processes, and their dysregulation can lead to disease. Creating predictive and interpretable models for these pathways is challenging because of the complexity of the pathways and of the…

Molecular Networks · Quantitative Biology 2023-10-02 Zijun Zhang , Adam R. Lamson , Michael Shelley , Olga Troyanskaya

Deep convolutional neural networks have proven their effectiveness, and have been acknowledged as the most dominant method for image classification. However, a severe drawback of deep convolutional neural networks is poor explainability.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Bin Wang , Wenbin Pei , Bing Xue , Mengjie Zhang

Deep convolutional neural networks accurately classify a diverse range of natural images, but may be easily deceived when designed, imperceptible perturbations are embedded in the images. In this paper, we design a multi-pronged training,…

Computer Vision and Pattern Recognition · Computer Science 2022-08-26 Nathaniel Dean , Dilip Sarkar

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Deep learning models have witnessed depth and pose estimation framework on unannotated datasets as a effective pathway to succeed in endoscopic navigation. Most current techniques are dedicated to developing more advanced neural networks to…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Junyang Wu , Yun Gu

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

We introduce a model-based deep learning architecture termed MoDL-MUSSELS for the correction of phase errors in multishot diffusion-weighted echo-planar MRI images. The proposed algorithm is a generalization of existing MUSSELS algorithm…

Computer Vision and Pattern Recognition · Computer Science 2019-10-23 Hemant Kumar Aggarwal , Merry P. Mani , Mathews Jacob

We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jimmy Wu , Bolei Zhou , Diondra Peck , Scott Hsieh , Vandana Dialani , Lester Mackey , Genevieve Patterson

Deep neural networks have shown their profound impact on achieving human level performance in visual saliency prediction. However, it is still unclear how they learn the task and what it means in terms of understanding human visual system.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Sai Phani Kumar Malladi , Jayanta Mukhopadhyay , Chaker Larabi , Santanu Chaudhury

To develop a deep-learning method for achieving fast high-resolution MR elastography from highly undersampled data without the need of high-quality training dataset. We first framed the deep neural network representation as a nonlinear…

Signal Processing · Electrical Eng. & Systems 2026-01-21 Xi Peng

The rapid adoption of transformer-based models in computational pathology has enabled prediction of molecular and clinical biomarkers from H&E whole-slide images, yet interpretability has not kept pace with model complexity. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marco Gustav , Fabian Wolf , Christina Glasner , Nic G. Reitsam , Stefan Schulz , Kira Aschenbroich , Bruno Märkl , Sebastian Foersch , Jakob Nikolas Kather

Medical image segmentation typically demands extensive dense annotations for model training, which is both time-consuming and skill-intensive. To mitigate this burden, exemplar-based medical image segmentation methods have been introduced…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Qing En , Yuhong Guo

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

Despite their impact on the society, deep neural networks are often regarded as black-box models due to their intricate structures and the absence of explanations for their decisions. This opacity poses a significant challenge to AI systems…

Machine Learning · Computer Science 2024-07-18 Biagio La Rosa

The use of photo-activated fluorescent molecules to create long sequences of low emitter-density diffraction-limited images enables high-precision emitter localization, but at the cost of low temporal resolution. We suggest combining…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Gili Dardikman-Yoffe , Yonina C. Eldar

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Nchongmaje Ndipenocha , Alina Mirona , Kezhi Wanga , Yongmin Li

We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Shaojie Li , Zhaoshuo Diao

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao