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A complete understanding of the brain requires an integrated description of the numerous scales of neural organization. It means studying the interplay of genes, synapses, and even whole brain regions which ultimately leads to different…

Neurons and Cognition · Quantitative Biology 2022-08-09 Charley Presigny , Fabrizio De Vico Fallani

The hippocampus is one of the most studied neuroanatomical structures due to its involvement in attention, learning, and memory as well as its atrophy in ageing, neurological, and psychiatric diseases. Hippocampal shape changes, however,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Kersten Diers , Hannah Baumeister , Frank Jessen , Emrah Düzel , David Berron , Martin Reuter

How human cognitive abilities are formed has long captivated researchers. However, a significant challenge lies in developing meaningful methods to measure these complex processes. With the advent of large language models (LLMs), which now…

Computation and Language · Computer Science 2025-03-04 Yao Yao , Yifei Yang , Xinbei Ma , Dongjie Yang , Zhuosheng Zhang , Zuchao Li , Hai Zhao

Timely, accurate and reliable assessment of fetal brain development is essential to reduce short and long-term risks to fetus and mother. Fetal MRI is increasingly used for fetal brain assessment. Three key biometric linear measurements…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Netanell Avisdris , Bossmat Yehuda , Ori Ben-Zvi , Daphna Link-Sourani , Liat Ben-Sira , Elka Miller , Elena Zharkov , Dafna Ben Bashat , Leo Joskowicz

The accurate quantification of brain age from MRI has emerged as an important biomarker of brain health. However, existing approaches are often restricted to narrow age ranges and single-modality MRI data, limiting their capacity to capture…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Dingyi Zhang , Ruiying Liu , Yun Wang

The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

Biological Physics · Physics 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

The development of automated tools for brain morphometric analysis in infants has lagged significantly behind analogous tools for adults. This gap reflects the greater challenges in this domain due to: 1) a smaller-scaled region of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Lilla Zöllei , Juan Eugenio Iglesias , Yangming Ou , P. Ellen Grant , Bruce Fischl

This paper introduces the concept of a bi-scale metric for use in the cooperative phase of the self-organizing map (SOM) algorithm. Use of a bi-scale metric allows segmentation of the map into a number of regions, corresponding to…

Neural and Evolutionary Computing · Computer Science 2018-05-10 William H. Wilson

The analysis of complex networks has revealed patterns of organization in a variety of natural and artificial systems, including neuronal networks of the brain at multiple scales. In this paper, we describe a novel analysis of the…

Neurons and Cognition · Quantitative Biology 2015-06-26 Luciano da F. Costa , Olaf Sporns

Human brain networks can be characterized at different temporal or spatial scales given by the age of the subject or the spatial resolution of the neuroimaging method. Integration of data across scales can only be successful if the combined…

The body plan of the fruit fly is determined by the expression of just a handful of genes. We show that the spatial patterns of expression for several of these genes scale precisely with the size of the embryo. Concretely, discrete…

Understanding the mechanical behavior of brain tissue is crucial for advancing both fundamental neuroscience and clinical applications. Yet, accurately measuring these properties remains challenging due to the brain unique mechanical…

The emerging field of the Science of Cities has unveiled previously undiscovered facets of urban life. Contrary to the expectation of chaotic behaviour influenced solely by cultural and geographic factors, cities globally exhibit universal…

Physics and Society · Physics 2025-10-20 Airton Deppman

Unmeasured, spatially-structured factors can confound associations between spatial environmental exposures and health outcomes. Adding flexible splines to a regression model is a simple approach for spatial confounding adjustment, but the…

Applications · Statistics 2020-06-22 Joshua P. Keller , Adam A. Szpiro

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

Neuronal cell bodies mostly reside in the cerebral cortex. The study of this thin and highly convoluted surface is essential for understanding how the brain works. The analysis of surface data is, however, challenging due to the high…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Karthik Gopinath , Christian Desrosiers , Herve Lombaert

The material bases of information - paper, computer discs - usually scale with information quantity. Large quantities of information usually require large material bases. Conventional wisdom has it that human long-term memory locates within…

Neurons and Cognition · Quantitative Biology 2014-06-05 Donald R. Forsdyke

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Recent studies suggest that the representations learned by large language models (LLMs) are partially aligned to those of the human brain. However, whether and why this alignment score arises from a similar sequence of computations remains…

Machine Learning · Computer Science 2025-12-02 Joséphine Raugel , Stéphane d'Ascoli , Jérémy Rapin , Valentin Wyart , Jean-Rémi King

Recent observation for scale invariant neural avalanches in the brain have been discussed in details in the scientific literature. We point out, that these results do not necessarily imply that the properties of the underlying neural…

Disordered Systems and Neural Networks · Physics 2015-06-11 Claudius Gros , Dimitrije Markovic