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Precision medicine is a paradigm shift in healthcare relying heavily on genomics data. However, the complexity of biological interactions, the large number of genes as well as the lack of comparisons on the analysis of data, remain a…
Genomic selection (GS) is a technique that plant breeders use to select individuals to mate and produce new generations of species. Allocation of resources is a key factor in GS. At each selection cycle, breeders are facing the choice of…
Decoding-based regression, which reformulates regression as a sequence generation task, has emerged as a promising paradigm of applying large language models for numerical prediction. However, its progress is hindered by the misalignment…
A big challenge in branch and bound lies in identifying the optimal node within the search tree from which to proceed. Current state-of-the-art selectors utilize either hand-crafted ensembles that automatically switch between naive sub-node…
In class-incremental semantic segmentation, we have no access to the labeled data of previous tasks. Therefore, when incrementally learning new classes, deep neural networks suffer from catastrophic forgetting of previously learned…
Curation of large fully supervised datasets has become one of the major roadblocks for machine learning. Weak supervision provides an alternative to supervised learning by training with cheap, noisy, and possibly correlated labeling…
This dissertation explores the application of machine learning in molecular biology, focusing on gene expression regulation and cellular behavior at the single-cell level. Using modern neural networks, the research addresses key challenges…
Representation learning has been proven to play an important role in the unprecedented success of machine learning models in numerous tasks, such as machine translation, face recognition and recommendation. The majority of existing…
Semi-supervised learning leverages unlabeled data to enhance model performance, addressing the limitations of fully supervised approaches. Among its strategies, pseudo-supervision has proven highly effective, typically relying on one or…
In this paper, we propose a new wrapper feature selection approach with partially labeled training examples where unlabeled observations are pseudo-labeled using the predictions of an initial classifier trained on the labeled training set.…
Supervised-learning based person re-identification (re-id) require a large amount of manual labeled data, which is not applicable in practical re-id deployment. In this work, we propose a Support Pair Active Learning (SPAL) framework to…
Given an unlabeled dataset and an annotation budget, we study how to selectively label a fixed number of instances so that semi-supervised learning (SSL) on such a partially labeled dataset is most effective. We focus on selecting the right…
In the fast-evolving field of artificial intelligence, where models are increasingly growing in complexity and size, the availability of labeled data for training deep learning models has become a significant challenge. Addressing complex…
Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…
Learning generalized models from biased data is an important undertaking toward fairness in deep learning. To address this issue, recent studies attempt to identify and leverage bias-conflicting samples free from spurious correlations…
Semi-supervised multi-organ medical image segmentation aids physicians in improving disease diagnosis and treatment planning and reduces the time and effort required for organ annotation.Existing state-of-the-art methods train the labeled…
Plant diseases serve as one of main threats to food security and crop production. It is thus valuable to exploit recent advances of artificial intelligence to assist plant disease diagnosis. One popular approach is to transform this problem…
Supervised learning of convolutional neural networks (CNNs) can require very large amounts of labeled data. Labeling thousands or millions of training examples can be extremely time consuming and costly. One direction towards addressing…
Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…
Learning with noisy labels aims to ensure model generalization given a label-corrupted training set. The sample selection strategy achieves promising performance by selecting a label-reliable subset for model training. In this paper, we…