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The prevalent technique for DNA sequencing consists of two main steps: shotgun sequencing, where many randomly located fragments, called reads, are extracted from the overall sequence, followed by an assembly algorithm that aims to…

Genomics · Quantitative Biology 2016-01-28 Shirshendu Ganguly , Elchanan Mossel , Miklos Z. Racz

Motivated by mass-spectrometry protein sequencing, we consider a simply-stated problem of reconstructing a string from the multiset of its substring compositions. We show that all strings of length 7, one less than a prime, or one less than…

Discrete Mathematics · Computer Science 2014-03-12 Jayadev Acharya , Hirakendu Das , Olgica Milenkovic , Alon Orlitsky , Shengjun Pan

In recent years, the emergence of DNA storage systems has led to a widespread focus on the research of codes correcting insertions, deletions, and classic substitutions. During the initial investigation, Levenshtein discovered the VT codes…

Information Theory · Computer Science 2024-01-23 Yuhang Pi , Zhifang Zhang

In the \emph{trace reconstruction problem}, an unknown source string $x \in \{0,1\}^n$ is transmitted through a probabilistic \emph{deletion channel} which independently deletes each bit with some fixed probability $\delta$ and concatenates…

Data Structures and Algorithms · Computer Science 2020-12-09 Xi Chen , Anindya De , Chin Ho Lee , Rocco A. Servedio , Sandip Sinha

We consider the classic joint source-channel coding problem of transmitting a memoryless source over a memoryless channel. The focus of this work is on the long-standing open problem of finding the rate of convergence of the smallest…

Information Theory · Computer Science 2019-08-27 Yuval Kochman , Or Ordentlich , Yury Polyanskiy

The $k$-deck problem is concerned with finding the smallest positive integer $S(k)$ such that there exist at least two strings of length $S(k)$ that share the same $k$-deck, i.e., the multiset of subsequences of length $k$. We introduce the…

Combinatorics · Mathematics 2025-10-28 Jonas Golm , Mina Nahvi , Ryan Gabrys , Olgica Milenkovic

The deletion channel is the simplest point-to-point communication channel that models lack of synchronization. Despite significant effort, little is known about its capacity, and even less about optimal coding schemes. In this paper we…

Information Theory · Computer Science 2011-05-02 Yashodhan Kanoria , Andrea Montanari

The problem of error-control in random linear network coding is considered. A ``noncoherent'' or ``channel oblivious'' model is assumed where neither transmitter nor receiver is assumed to have knowledge of the channel transfer…

Information Theory · Computer Science 2008-03-25 Ralf Koetter , Frank Kschischang

The restoration lemma by Afek, Bremler-Barr, Kaplan, Cohen, and Merritt [Dist. Comp. '02] proves that, in an undirected unweighted graph, any replacement shortest path avoiding a failing edge can be expressed as the concatenation of two…

Data Structures and Algorithms · Computer Science 2023-06-06 Greg Bodwin , Merav Parter

We introduce the sum channel, a new channel model motivated by applications in distributed storage and DNA data storage. In the error-free case, it takes as input an $\ell$-row binary matrix and outputs an $(\ell+1)$-row matrix whose first…

Information Theory · Computer Science 2026-04-14 Lyan Abboud , Eitan Yaakobi

We consider the problem of designing low-redundancy codes in settings where one must correct deletions in conjunction with substitutions or adjacent transpositions; a combination of errors that is usually observed in DNA-based data storage.…

Information Theory · Computer Science 2021-12-21 Ryan Gabrys , Venkatesan Guruswami , João Ribeiro , Ke Wu

This work is motivated by the problem of error correction in bit-shift channels with the so-called $ (d,k) $ input constraints (where successive $ 1 $'s are required to be separated by at least $ d $ and at most $ k $ zeros, $ 0 \leq d < k…

Information Theory · Computer Science 2020-08-13 Mladen Kovačević

We study the following semi-deterministic setting of the joint source-channel coding problem: a deterministic source sequence (a.k.a. individual sequence) is transmitted via a memoryless channel, using delay-limited encoder and decoder,…

Information Theory · Computer Science 2021-09-29 Neri Merhav

We consider binary input deletion/substitution channels, which model certain types of synchronization errors encountered in practice. Specifically, we focus on the regime of small deletion and substitution probabilities, and by extending an…

Information Theory · Computer Science 2025-07-29 Mohammad Kazemi , Tolga M. Duman

Motivated by mutation processes occurring in in-vivo DNA-storage applications, a channel that mutates stored strings by duplicating substrings as well as substituting symbols is studied. Two models of such a channel are considered: one in…

Information Theory · Computer Science 2020-07-01 Yuanyuan Tang , Yonatan Yehezkeally , Moshe Schwartz , Farzad Farnoud

This paper examines linear binary codes capable of correcting one or more errors. For the single-error-correcting case, it is shown that the Hamming bound is achieved by a constructive method, and an exact expression for the minimal…

Information Theory · Computer Science 2025-12-16 Timofei Izhitskii

In this paper we consider the problem to reconstruct a $k$-uniform hypergraph from its line graph. In general this problem is hard. We solve this problem when the number of hyperedges containing any pair of vertices is bounded. Given an…

Combinatorics · Mathematics 2021-05-03 Amitava Bhattacharya , Aloysius Godinho , Pritam Majumder , Navin Singhi

In this paper, we derive an expression for the expected number of runs in a trace of a binary sequence $x \in \{0,1\}^n$ obtained by passing $x$ through a deletion channel that independently deletes each bit with probability $q$. We use…

Information Theory · Computer Science 2025-11-06 Shiv Pratap Singh Rathore , Navin Kashyap

In the trace reconstruction problem, the goal is to reconstruct an unknown string $x$ of length $n$ from multiple traces obtained by passing $x$ through the deletion channel. In the relaxed problem of $approximate$ trace reconstruction, the…

Probability · Mathematics 2021-07-15 Zachary Chase , Yuval Peres

A permutation code is a nonlinear code whose codewords are permutation of a set of symbols. We consider the use of permutation code in the deletion channel, and consider the symbol-invariant error model, meaning that the values of the…

Information Theory · Computer Science 2024-11-14 Minhan Gao , Kenneth W. Shum