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High fidelity segmentation of both macro and microvascular structure of the retina plays a pivotal role in determining degenerative retinal diseases, yet it is a difficult problem. Due to successive resolution loss in the encoding phase…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Kenton M. Sanders , Salah A. Baker

We introduce a new technique for generating retinal fundus images that have anatomically accurate vascular structures, using diffusion models. We generate artery/vein masks to create the vascular structure, which we then condition to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Sojung Go , Younghoon Ji , Sang Jun Park , Soochahn Lee

Deep learning has achieved remarkable success in medical image classification. However, its clinical application is often hindered by data heterogeneity caused by variations in scanner vendors, imaging protocols, and operators. Approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Yaoyao Zhu , Xiuding Cai , Yingkai Wang , Yu Yao , Xu Luo , Zhongliang Fu

Domain Adaptation is a technique to address the lack of massive amounts of labeled data in unseen environments. Unsupervised domain adaptation is proposed to adapt a model to new modalities using solely labeled source data and unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Thong Vo , Naimul Khan

This study introduces a novel framework for enhancing domain generalization in medical imaging, specifically focusing on utilizing unlabelled multi-view colour fundus photographs. Unlike traditional approaches that rely on single-view…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Ze Chen , Gongyu Zhang , Jiayu Huo , Joan Nunez do Rio , Charalampos Komninos , Yang Liu , Rachel Sparks , Sebastien Ourselin , Christos Bergeles , Timothy Jackson

The annotation scarcity of medical image segmentation poses challenges in collecting sufficient training data for deep learning models. Specifically, models trained on limited data may not generalize well to other unseen data domains,…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Heng Li , Haojin Li , Wei Zhao , Huazhu Fu , Xiuyun Su , Yan Hu , Jiang Liu

Vessel structure is one of the most important parts of the retina which physicians can detect many diseases by analysing its features. Localization of blood vessels in retina images is an important process in medical image analysis. This…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Vahid Mohammadi Safarzadeh

Data augmentation is widely used to enhance generalization in visual classification tasks. However, traditional methods struggle when source and target domains differ, as in domain adaptation, due to their inability to address domain gaps.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Khawar Islam , Muhammad Zaigham Zaheer , Arif Mahmood , Karthik Nandakumar , Naveed Akhtar

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Manoj S H , Arya A Bosale

Deep learning models often encounter challenges in making accurate inferences when there are domain shifts between the source and target data. This issue is particularly pronounced in clinical settings due to the scarcity of annotated data…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Heng Li , Haojin Li , Jianyu Chen , Mingyang Ou , Hai Shu , Heng Miao

The appearance and structure of blood vessels in retinal images have an important role in diagnosis of diseases. This paper proposes a method for automatic retinal vessel segmentation. In this work, a novel preprocessing based on local…

Computer Vision and Pattern Recognition · Computer Science 2013-12-31 Saeid Fazli , Sevin Samadi

Medical image segmentation is a critical task in computer-aided diagnosis and treatment planning. However, deep learning models often struggle to generalize across datasets due to domain shifts arising from variations in imaging protocols,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Phuoc-Nguyen Bui , Van-Nguyen Pham , Duc-Tai Le , Junghyun Bum , Hyunseung Choo

Deep neural networks often suffer performance drops when test data distribution differs from training data. Domain Generalization (DG) aims to address this by focusing on domain-invariant features or augmenting data for greater diversity.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Nam Duong Tran , Nam Nguyen Phuong , Hieu H. Pham , Phi Le Nguyen , My T. Thai

Many deep learning based methods have been proposed for retinal vessel segmentation, however few of them focus on the connectivity of segmented vessels, which is quite important for a practical computer-aided diagnosis system on retinal…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Rui Xu , Tiantian Liu , Xinchen Ye , Yen-Wei Chen

Clinical magnetic-resonance (MR) protocols generate many T1 and T2 sequences whose appearance differs more than the acquisition sites that produce them. Existing domain-generalization benchmarks focus almost on cross-center shifts and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Zheyuan Zhang , Linkai Peng , Wanying Dou , Cuiling Sun , Halil Ertugrul Aktas , Andrea M. Bejar , Elif Keles , Gorkem Durak , Ulas Bagci

Precision in identifying and differentiating micro and macro blood vessels in the retina is crucial for the diagnosis of retinal diseases, although it poses a significant challenge. Current autoencoding-based segmentation approaches…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Rui Yang , Shunpu Zhang

Tackling domain shifts in multi-centre and multi-vendor data sets remains challenging for cardiac image segmentation. In this paper, we propose a generalisable segmentation framework for cardiac image segmentation in which multi-centre,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Hongwei Li , Jianguo Zhang , Bjoern Menze

Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support systems. Over the past decade, numerous architectures specifically tailored to medical imaging have emerged to address…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Vanessa Borst , Samuel Kounev

Computer-Aided Diagnosis systems are required to extract suitable information about retina and its changes. In particular, identifying objects of interest such as lesions and anatomical structures from the retinal images is a challenging…

Medical Physics · Physics 2020-05-20 Meysam Tavakoli , Mahdieh Nazar , Alireza Mehdizadeh

Deep Neural Networks (DNNs)-based semantic segmentation models trained on a source domain often struggle to generalize to unseen target domains, i.e., a domain gap problem. Texture often contributes to the domain gap, making DNNs vulnerable…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Sunghwan Kim , Dae-hwan Kim , Hoseong Kim
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